Zobrazeno 1 - 10
of 125
pro vyhledávání: '"TATSUO MICHIUE"'
Autor:
Kazuki Kitamura, Takayoshi Yamamoto, Haruki Ochi, Makoto Suzuki, Nanoka Suzuki, Takeshi Igawa, Tadashi Yoshida, Mitsuru Futakuchi, Hajime Ogino, Tatsuo Michiue
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Cancer treatment is still challenging because the disease is often caused by multiple mutations. Although genomic studies have identified many oncogenes and tumor suppressor genes, gene sets involved in tumorigenesis remain poorly understood
Externí odkaz:
https://doaj.org/article/a41cf6e9249f43b6a37272f2154a213e
Autor:
Fuad Gandhi Torizal, Qiao You Lau, Masato Ibuki, Yoshikazu Kawai, Masato Horikawa, Masataka Minami, Tatsuo Michiue, Ikki Horiguchi, Masaki Nishikawa, Yasuyuki Sakai
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Although human pluripotent stem cell culture is routine, daily media changes, high cost of growth factors required in pluripotent cell media, and reproducibility of differentiation are an obstacle for the mass production of hPSCs. Here, Torizal et al
Externí odkaz:
https://doaj.org/article/a9aeb1e539894f8bb934595d323399c7
Publikováno v:
BMC Ecology and Evolution, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background hes genes are chordate homologs of Drosophila genes, hairy and enhancer of split, which encode a basic helix-loop-helix (bHLH) transcriptional repressor with a WRPW motif. Various developmental functions of hes genes, including ea
Externí odkaz:
https://doaj.org/article/9e7bbd385db84a968baa8e444b609a2b
Autor:
Takayoshi Yamamoto, Yuta Kambayashi, Yuta Otsuka, Boni A Afouda, Claudiu Giuraniuc, Tatsuo Michiue, Stefan Hoppler
Publikováno v:
eLife, Vol 11 (2022)
Secreted molecules called morphogens govern tissue patterning in a concentration-dependent manner. However, it is still unclear how reproducible patterning can be achieved with diffusing molecules, especially when that patterning concerns differentia
Externí odkaz:
https://doaj.org/article/97c0fc2f7b5b4e01abbb1e96da78fe79
Autor:
Tatsuo Michiue, Kohei Tsukano
Publikováno v:
Journal of Developmental Biology, Vol 10, Iss 3, p 35 (2022)
Intracellular signaling pathways are essential to establish embryonic patterning, including embryonic axis formation. Ectodermal patterning is also governed by a series of morphogens. Four ectodermal regions are thought to be controlled by morphogen
Externí odkaz:
https://doaj.org/article/713e2a18d65d4f2a82473c88e686cf3e
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254373 (2021)
Human induced pluripotent stem cells (hiPSCs) are considered a promising source of pancreatic β-cells for the treatment of diabetes. However, this approach is limited by issues such as low efficiency and high cost. Here, we have developed a new prot
Externí odkaz:
https://doaj.org/article/938938cb370142d4a928cbde5fdd4754
Autor:
Junfeng WANG, Masahiro ITO, Wenhao ZHONG, Shukei SUGITA, Tatsuo MICHIUE, Takashi TSUBOI, Tetsuya KITAGUCHI, Takeo MATSUMOTO
Publikováno v:
Journal of Biomechanical Science and Engineering, Vol 11, Iss 4, Pp 16-00504-16-00504 (2016)
Tension in actin filaments plays crucial roles in multiple cellular functions, although little is known about tension dynamics of cells during adhesion to substrates. In this study, we visualized intracellular tension in actin filaments using a newly
Externí odkaz:
https://doaj.org/article/2e8d877cf6c74497881a49f83eaee260
Autor:
Siti Razila Abdul Razak, Kazuko Ueno, Naoya Takayama, Naoki Nariai, Masao Nagasaki, Rika Saito, Hideto Koso, Chen-Yi Lai, Miyako Murakami, Koichiro Tsuji, Tatsuo Michiue, Hiromitsu Nakauchi, Makoto Otsu, Sumiko Watanabe
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73532 (2013)
Using quantitative PCR-based miRNA arrays, we comprehensively analyzed the expression profiles of miRNAs in human and mouse embryonic stem (ES), induced pluripotent stem (iPS), and somatic cells. Immature pluripotent cells were purified using SSEA-1
Externí odkaz:
https://doaj.org/article/41d27263db444054b3a4adbb64ea2668
Autor:
Aya Miyazaki, Kentaro Ishii, Satoshi Yamashita, Susumu Nejigane, Shinya Matsukawa, Yuzuru Ito, Yasuko Onuma, Makoto Asashima, Tatsuo Michiue
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46630 (2012)
BACKGROUND:In Xenopus early embryogenesis, various genes are involved with mesoderm formation. In particular, dorsal mesoderm contains the organizer region and induces neural tissues through the inhibition of bone morphogenetic protein (BMP) signalin
Externí odkaz:
https://doaj.org/article/f667d49642654440a9c3679b2ca549e0
Autor:
Yohei Hayashi, Techuan Chan, Masaki Warashina, Masakazu Fukuda, Takashi Ariizumi, Koji Okabayashi, Naoya Takayama, Makoto Otsu, Koji Eto, Miho Kusuda Furue, Tatsuo Michiue, Kiyoshi Ohnuma, Hiromitsu Nakauchi, Makoto Asashima
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14099 (2010)
BackgroundThe successful establishment of human induced pluripotent stem cells (hiPSCs) has increased the possible applications of stem cell research in biology and medicine. In particular, hiPSCs are a promising source of cells for regenerative medi
Externí odkaz:
https://doaj.org/article/c18b4106c0c149c0bbff7552180f8701