The Recombinant Form of Trypanosoma cruzi P21 Controls Infection by Modulating Host Immune Response

Autor: Flávia Alves Martins, Marlus Alves dos Santos, Júlia de Gouveia Santos, Aline Alves da Silva, Bruna Cristina Borges, Mylla Spirandelli da Costa, Paula Cristina Brígido Tavares, Samuel Cota Teixeira, Rebecca Tavares e Silva Brígido, Thaise Lara Teixeira, Cassiano Costa Rodrigues, Nadjania Saraiva de Lira Silva, Rayane Cristina de Oliveira, Laura Caroline de Faria, Marcela Rezende Lemes, Renata Graciele Zanon, Tatiana Carla Tomiosso, Juliana Reis Machado, Marcos Vinicius da Silva, Carlo José Freire Oliveira, Claudio Vieira da Silva

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Trypanosoma cruzi P21 protein (P21) is a putative secreted and immunomodulatory molecule with potent bioactive properties such as induction of phagocytosis and actin cytoskeleton polymerization. Despite the bioactive properties described so far, the

Externí odkaz: https://doaj.org/article/afa149cf218941519a88ce1ba6e82709

α-zingiberene, a sesquiterpene from essential oil from leaves of Casearia sylvestris, suppresses inflammatory angiogenesis and stimulates collagen deposition in subcutaneous implants in mice

Autor: Bruno Antonio Ferreira, Ricardo Ferreira Silva, Francyelle Borges Rosa de Moura, Carolina Tannús Narduchi, Simone Ramos Deconte, Patricia Sartorelli, Tatiana Carla Tomiosso, João Henrique Ghilardi Lago, Fernanda de Assis Araújo

Publikováno v: Natural Product Research. 36:5858-5862

α-zingiberene is a phytochemical of the sesquiterpenes class, the major constituent of the essential oil from the leaves of Casearia sylvestris, a plant widely used in traditional medicine for the treatment of inflammatory diseases, tumours, and bac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb44b38cf997a80369e82fa6ed0c4db3
https://doi.org/10.1080/14786419.2021.2019729

Recombinant Protein rP21 from Trypanosoma cruzi has Effect on Inflammation, Angiogenesis and Fibrogenesis in Skin Wound Model C57BL/6 Mouse

Autor: Tatiana Carla Tomiosso, Bruno Antonio Ferreira, Flávia Alves Martins, Fernanda de Assis Araújo, Jeranice Silva Barbosa, Claudio Vieira da Silva, José Augusto Leoncio Gomide, Daniele Lisboa Ribeiro, Francyelle Borges Rosa de Moura, Elusca Helena Muniz

Publikováno v: Advances in Research. :28-37

Aims: Recombinant proteins rP2 has demonstrated biological activity in inflammation by acting on the recruitment of leukocytes and by inducing phagocytosis, also modulating the processes of angiogenesis and fibrogenesis in different experimental mode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e09a1be8929f52342544eb8ef5302cf0
https://doi.org/10.9734/air/2021/v22i130285

TiO2 Nanocrystals and Annona crassiflora Polyphenols Used Alone or Mixed Impact Differently on Wound Repair

Autor: FRANCYELLE B.R. DE MOURA, BRUNO ANTONIO FERREIRA, ELUSCA HELENA MUNIZ, RINARA A. SANTOS, JOSÉ AUGUSTO L. GOMIDE, ALLISSON B. JUSTINO, ANIELLE CHRISTINE A. SILVA, NOELIO O. DANTAS, DANIELE L. RIBEIRO, FERNANDA A. ARAÚJO, FOUED S. ESPINDOLA, TATIANA CARLA TOMIOSSO

Publikováno v: Anais da Academia Brasileira de Ciências v.94 n.2 2022
Anais da Academia Brasileira de Ciências
Academia Brasileira de Ciências (ABC)
instacron:ABC
Anais da Academia Brasileira de Ciências, Volume: 94, Issue: 2, Article number: e20210230, Published: 08 JUL 2022

Wounds treated with TiO2 nanoparticles (TiO2-NPs) show an improvement in healing time. However, little is known about the parameters that can contribute to this result. On the other hand, the treatment of wounds with polyphenols is widely known. Thes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8f0037ba2240ce085ad908f6df23c4
https://doi.org/10.1590/0001-3765202220210230

Alternagin-C, a disintegrin-like protein from Bothrops alternatus venom, attenuates inflammation and angiogenesis and stimulates collagen deposition of sponge-induced fibrovascular tissue in mice

Autor: Simone Ramos Deconte, Tatiana Carla Tomiosso, Bruno Antonio Ferreira, Silvia Passos Andrade, Patty Karina dos Santos, Fernanda de Assis Araújo, Heloisa Sobreiro Selistre de Araújo, Luis Fernando Gonçalves Rabelo

Publikováno v: International Journal of Biological Macromolecules. 140:653-660

Alternagin-C (ALT-C), a disintegrin-like protein obtained from the venom of Bothrops alternatus, is able to modulate cellular behaviors such as adhesion, migration and proliferation, as well as the production of various growth factors via α2β1 inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e666beb365eb34f9646a0783557f358
https://doi.org/10.1016/j.ijbiomac.2019.08.171