Zobrazeno 1 - 10
of 145
pro vyhledávání: '"TASK channels"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 344 (2022)
Somatic expressions of either heteromeric TASK1/3 or homomeric TASK1/1 channels have been reported in various neurons, while expression of homomeric TASK3/3 channels has been re-ported only in dendrites. However, it is not known why homomeric TASK3/3
Externí odkaz:
https://doaj.org/article/a6aff21e1b6b492a979840c2631c4abd
Publikováno v:
Molecules, Vol 27, Iss 23, p 8296 (2022)
TWIK-related acid-sensitive K+ (TASK) channels, including TASK-1, TASK-3, and TASK-5, are important members of the two-pore domain potassium (K2P) channel family. TASK-5 is not functionally expressed in the recombinant system. TASK channels are very
Externí odkaz:
https://doaj.org/article/21f15cf81bcf4cee9e502a7e3d63c702
Autor:
Fang Yuan, Hanqiao Wang, Jiaqi Feng, Ziqian Wei, Hongxiao Yu, Xiangjian Zhang, Yi Zhang, Sheng Wang
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Leptin is an adipose-derived hormone that plays an important role in the regulation of breathing. It has been demonstrated that obesity-related hypoventilation or apnea is closely associated with leptin signaling pathways. Perturbations of leptin sig
Externí odkaz:
https://doaj.org/article/ef686d290c5044bfa9a332b3e4838390
Autor:
David Ramírez, Guierdy Concha, Bárbara Arévalo, Luis Prent-Peñaloza, Leandro Zúñiga, Aytug K. Kiper, Susanne Rinné, Miguel Reyes-Parada, Niels Decher, Wendy González, Julio Caballero
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 16, p 4014 (2019)
TASK-3 is a two-pore domain potassium (K2P) channel highly expressed in the hippocampus, cerebellum, and cortex. TASK-3 has been identified as an oncogenic potassium channel and it is overexpressed in different cancer types. For this reason, the deve
Externí odkaz:
https://doaj.org/article/e3b846f62ae345a2a13e80d95e6487b4
Autor:
David Ramírez, Mauricio Bedoya, Aytug K. Kiper, Susanne Rinné, Samuel Morales-Navarro, Erix W. Hernández-Rodríguez, Francisco V. Sepúlveda, Niels Decher, Wendy González
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2252 (2019)
TASK-3 potassium (K+) channels are highly expressed in the central nervous system, regulating the membrane potential of excitable cells. TASK-3 is involved in neurotransmitter action and has been identified as an oncogenic K+ channel. For this reason
Externí odkaz:
https://doaj.org/article/791b4efc58684ec695571e6fe0f4795f
Akademický článek
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Publikováno v:
Am J Physiol Heart Circ Physiol
Tandem pore domain acid-sensitive K+ (TASK) channels are present in cardiac tissue; however, their contribution to cardiac pathophysiology is not well understood. Here, we investigate the role of TASK-1 and TASK-3 in the pathogenesis of cardiac dysfu
Autor:
Sven G. Meuth, Christoph Kleinschnitz, Tilman Broicher, Madeleine Austinat, Stefan Braeuninger, Stefan Bittner, Stephan Fischer, Douglas A. Bayliss, Thomas Budde, Guido Stoll, Heinz Wiendl
Publikováno v:
Neurobiology of Disease, Vol 33, Iss 1, Pp 1-11 (2009)
Oxygen depletion (O2) and a decrease in pH are initial pathophysiological events in stroke development, but secondary mechanisms of ischemic cell death are incompletely understood. By patch-clamp recordings of brain slice preparations we show that TA
Externí odkaz:
https://doaj.org/article/d3a937458cbf4aa49ee252fbcd594bea
Akademický článek
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Autor:
Samuel A. Neymotin, Michele Migliore, Craig Kelley, Salvador Dura-Bernal, Nicholas T. Carnevale, Srdjan D. Antic, William W. Lytton
Publikováno v:
Journal of neurophysiology 125 (2021): 1501–1516. doi:10.1152/jn.00015.2021
info:cnr-pdr/source/autori:Kelley C.; Dura-Bernal S.; Neymotin S.A.; Antic S.D.; Carnevale N.T.; Migliore M.; Lytton W.W./titolo:Effects of Ih and TASK-like shunting current on dendritic impedance in layer 5 pyramidal-tract neurons/doi:10.1152%2Fjn.00015.2021/rivista:Journal of neurophysiology/anno:2021/pagina_da:1501/pagina_a:1516/intervallo_pagine:1501–1516/volume:125
info:cnr-pdr/source/autori:Kelley C.; Dura-Bernal S.; Neymotin S.A.; Antic S.D.; Carnevale N.T.; Migliore M.; Lytton W.W./titolo:Effects of Ih and TASK-like shunting current on dendritic impedance in layer 5 pyramidal-tract neurons/doi:10.1152%2Fjn.00015.2021/rivista:Journal of neurophysiology/anno:2021/pagina_da:1501/pagina_a:1516/intervallo_pagine:1501–1516/volume:125
Pyramidal neurons in neocortex have complex input-output relationships that depend on their morphologies, ion channel distributions, and the nature of their inputs, but which cannot be replicated by simple integrate-and-fire models. The impedance pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e9f837c2f1697853bdb96ed1b3f419
https://doi.org/10.1101/2021.01.08.425962
https://doi.org/10.1101/2021.01.08.425962