Zobrazeno 1 - 10
of 50
pro vyhledávání: '"TARO TOBO"'
Autor:
Kosuke Hirose, Takeo Toshima, Taro Tobo, Satohiro Kai, Masakazu Hirakawa, Satoshi Higuchi, Takashi Ofuchi, Kiyotaka Hosoda, Yusuke Yonemura, Yuichi Hisamatsu, Takaaki Masuda, Shinichi Aishima, Koshi Mimori
Publikováno v:
Surgical Case Reports, Vol 10, Iss 1, Pp 1-6 (2024)
Abstract Background Nodular regenerative hyperplasia (NRH) is a rare disease that presents pathologically as diffuse hepatic nodules without fibrous septa. It is believed to be caused by vasculopathy against a background of various systemic diseases,
Externí odkaz:
https://doaj.org/article/8c48f90f05b54d0680556cfd1e5f824a
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 484-490 (2023)
Here, we present a 69-year-old female with advanced neuroendocrine carcinoma (NEC) of colon with multiple liver, bone, and kidney metastases who developed Trousseau’s syndrome. The patient received etoposide plus cisplatin (EP) as the first-line th
Externí odkaz:
https://doaj.org/article/41118f6a933a41d4afb2f283d63f0e7b
Autor:
Hirofumi Ohmura, Taro Tobo, Yuki Ando, Takaaki Masuda, Koshi Mimori, Koichi Akashi, Eishi Baba
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Here, we present the case of a 42-year-old female who developed acute pancreatitis due to dexamethasone during adjuvant chemotherapy for early triple negative breast cancer (TNBC). The patient received partial mastectomy and sentinel lymph node biops
Externí odkaz:
https://doaj.org/article/bdf4190d527c40e4aa8905ea9b6e0601
Autor:
Yuki Ozato, Yasuhiro Kojima, Yuta Kobayashi, Yuuichi Hisamatsu, Takeo Toshima, Yusuke Yonemura, Takaaki Masuda, Kouichi Kagawa, Yasuhiro Goto, Mitsuaki Utou, Mituko Fukunaga, Ayako Gamachi, Kiyomi Imamura, Yuta Kuze, Junko Zenkoh, Ayako Suzuki, Atsushi Niida, Haruka Hirose, Shuto Hayashi, Jun Koseki, Eiji Oki, Satoshi Fukuchi, Kazunari Murakami, Taro Tobo, Satoshi Nagayama, Mamoru Uemura, Takeharu Sakamoto, Masanobu Oshima, Yuichiro Doki, Hidetoshi Eguchi, Masaki Mori, Takeshi Iwasaki, Yoshinao Oda, Tatsuhiro Shibata, Yutaka Suzuki, Teppei Shimamura, Koshi Mimori
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111929- (2023)
Summary: The cellular interactions in the tumor microenvironment of colorectal cancer (CRC) are poorly understood, hindering patient treatment. In the current study, we investigate whether events occurring at the invasion front are of particular impo
Externí odkaz:
https://doaj.org/article/36523fb8ccbc455a9c49d7317c9ee01e
Autor:
Qingjiang Hu, Takaaki Masuda, Kensuke Koike, Kuniaki Sato, Taro Tobo, Shotaro Kuramitsu, Akihiro Kitagawa, Atsushi Fujii, Miwa Noda, Yusuke Tsuruda, Hajime Otsu, Yosuke Kuroda, Shuhei Ito, Eiji Oki, Koshi Mimori
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Gastric cancer (GC) is one of the most lethal malignant tumors. To improve the prognosis of GC, the identification of novel driver genes as therapeutic targets is in urgent need. Here, we aimed to identify novel driver genes and clarify thei
Externí odkaz:
https://doaj.org/article/c6eaaf00e7784c2cbd3f96cb47f9a420
Autor:
Kenichi Mochizuki, Shin-ei Kudo, Kazuki Kato, Koki Kudo, Yushi Ogawa, Yuta Kouyama, Yuki Takashina, Katsuro Ichimasa, Taro Tobo, Takeo Toshima, Yuichi Hisamatsu, Yusuke Yonemura, Takaaki Masuda, Hideyuki Miyachi, Fumio Ishida, Tetsuo Nemoto, Koshi Mimori
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Background Colorectal cancer (CRC) can be classified into four consensus molecular subtypes (CMS) according to genomic aberrations and gene expression profiles. CMS is expected to be useful in predicting prognosis and selecting chemotherapy regimens.
Externí odkaz:
https://doaj.org/article/58fc2a9ccf2f4423a7be32a8289a8a7c
Autor:
Kuniaki Sato, Takaaki Masuda, Qingjiang Hu, Taro Tobo, Sarah Gillaspie, Atsushi Niida, Mackenzie Thornton, Yousuke Kuroda, Hidetoshi Eguchi, Takashi Nakagawa, Katsura Asano, Koshi Mimori
Publikováno v:
EBioMedicine, Vol 44, Iss , Pp 387-402 (2019)
Background: Translational reprogramming through controlled initiation from non-AUG start codons is considered a crucial driving force in tumorigenesis and tumor progression. However, its clinical impact and underlying mechanism are not fully understo
Externí odkaz:
https://doaj.org/article/2de3a6e8311344458ad956e83ed0a466
Autor:
Qingjiang Hu, Takaaki Masuda, Shotaro Kuramitsu, Taro Tobo, Kuniaki Sato, Shinya Kidogami, Sho Nambara, Masami Ueda, Yusuke Tsuruda, Yosuke Kuroda, Shuhei Ito, Eiji Oki, Masaki Mori, Koshi Mimori
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0241140 (2020)
BackgroundPeritoneal dissemination (PD) frequently occurs in gastric cancer (GC) and is incurable. In this study, we aimed to identify novel PD-associated genes and clarify their clinical and biological significance in GC.Materials and methodsWe iden
Externí odkaz:
https://doaj.org/article/cb925bc3895a48e1824016e77fd78cb0
A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer
Autor:
Tomoko Saito, Atsushi Niida, Ryutaro Uchi, Hidenari Hirata, Hisateru Komatsu, Shotaro Sakimura, Shuto Hayashi, Sho Nambara, Yosuke Kuroda, Shuhei Ito, Hidetoshi Eguchi, Takaaki Masuda, Keishi Sugimachi, Taro Tobo, Haruto Nishida, Tsutomu Daa, Kenichi Chiba, Yuichi Shiraishi, Tetsuichi Yoshizato, Masaaki Kodama, Tadayoshi Okimoto, Kazuhiro Mizukami, Ryo Ogawa, Kazuhisa Okamoto, Mitsutaka Shuto, Kensuke Fukuda, Yusuke Matsui, Teppei Shimamura, Takanori Hasegawa, Yuichiro Doki, Satoshi Nagayama, Kazutaka Yamada, Mamoru Kato, Tatsuhiro Shibata, Masaki Mori, Hiroyuki Aburatani, Kazunari Murakami, Yutaka Suzuki, Seishi Ogawa, Satoru Miyano, Koshi Mimori
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Advanced colorectal cancers are characterised by intra-tumour heterogeneity dictated by neutral evolution. Here the authors analyse early colorectal tumours by whole-exome sequencing and find that Darwinian evolution determines the fate of early lesi
Externí odkaz:
https://doaj.org/article/23dc0cb8e5fb48bfbd8d0dc7663ee372
Rab27b, a Regulator of Exosome Secretion, Is Associated With Peritoneal Metastases in Gastric Cancer
Autor:
SHO NAMBARA, TAKAAKI MASUDA, KOSUKE HIROSE, QINGJIANG HU, TARO TOBO, YUKI OZATO, JUNJI KURASHIGE, YOSHIKI HIRAKI, YUICHI HISAMATSU, TOMOHIRO IGUCHI, KEISHI SUGIMACHI, EIJI OKI, TOMOHARU YOSHIZUMI, KOSHI MIMORI
Publikováno v:
Cancer Genomics Proteomics
Background/Aim: Peritoneal metastasis (PM) of gastric cancer (GC) leads to poor clinical outcomes. Tumor-derived exosomes promote metastasis via communication between tumor cells and host cells. In this study, we investigated the effect of Rab27, whi