Zobrazeno 1 - 10
of 7 611
pro vyhledávání: '"TARGET GENES"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Breast cancer is one of the deadliest malignancies in women worldwide. Zinc finger protein 32 (ZNF32) has been reported to be involved in autophagy and stem cell like properties of breast cancer cells. However, the effects, mechanisms, targe
Externí odkaz:
https://doaj.org/article/3d53e5be6742443582614a0847496f21
Autor:
Sajida Ashraf, Muhammad Sufyan, Bilal Aslam, Hina Khalid, Norah A. Albekairi, Abdulrahman Alshammari, Metab Alharbi, Muhammad Atif Nisar, Mohsin Khurshid, Usman Ali Ashfaq
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Chikungunya virus (CHIKV) is a single-stranded RNA virus belonging to the genus Alphavirus and is responsible for causing Chikungunya fever, a type of arboviral fever. Despite extensive research, the pathogenic mechanism of CHIKV within host
Externí odkaz:
https://doaj.org/article/3da67614ecfa4b93977c684d7d97c63f
Autor:
Linlin Zhuang, Jiansen Gong, Ping Zhang, Di Zhang, Ying Zhao, Jianbo Yang, Guofang Liu, Yu Zhang, Qiuping Shen
Publikováno v:
Discover Nano, Vol 19, Iss 1, Pp 1-29 (2024)
Abstract Salmonella, the prevailing zoonotic pathogen within the Enterobacteriaceae family, holds the foremost position in global bacterial poisoning incidents, thereby signifying its paramount importance in public health. Consequently, the imperativ
Externí odkaz:
https://doaj.org/article/22b3f4cd5b104e21950de5d3c3b762df
Autor:
Renata Gruszka, Jakub Zakrzewski, Emilia Nowosławska, Wiesława Grajkowska, Magdalena Zakrzewska
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Alterations in miRNA levels have been observed in various types of cancer, impacting numerous cellular processes and increasing their potential usefulness in combination therapies also in brain tumors. Recent advances in understanding the ge
Externí odkaz:
https://doaj.org/article/4aaa3309b07641fca094dc3b7895707a
Autor:
Ranjini Ghosh Dastidar, Julia Jaroslawska, Marjo Malinen, Tomi-Pekka Tuomainen, Jyrki K. Virtanen, Igor Bendik, Carsten Carlberg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Vitamin D modulates innate and adaptive immunity, the molecular mechanisms of which we aim to understand under human in vivo conditions. Therefore, we designed the study VitDHiD (NCT03537027) as a human investigation, in which 25 healthy ind
Externí odkaz:
https://doaj.org/article/6da6f992957342c4b2e5d9e476344c81
Publikováno v:
The Journal of Headache and Pain, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Currently, the treatment and prevention of migraine remain highly challenging. Mendelian randomization (MR) has been widely used to explore novel therapeutic targets. Therefore, we performed a systematic druggable genome-wide MR t
Externí odkaz:
https://doaj.org/article/f3529f01d2fe4d7aae83e6c7f610b825
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 2, Pp 350-358 (2024)
Background: Schizophrenia (SZ), a complex and chronic neuropsychiatric disorder affecting approximately 1 % of the general population, presents diagnostic challenges due to the absence of reliable biomarkers, and relying mainly on clinical observatio
Externí odkaz:
https://doaj.org/article/f88b0015a4e447429ab6a93de499bfdc
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background In the context of early sowing of maize as a promising adaptation strategy that could significantly reduce the negative effects of climate change, an in-depth understanding of mechanisms underlying plant response to low-temperatur
Externí odkaz:
https://doaj.org/article/939744f0ddb24f808fba3174c538f117
Publikováno v:
Journal of Functional Foods, Vol 121, Iss , Pp 106405- (2024)
Insomnia, affecting the quality of life of millions globally, necessitates urgent and effective treatment strategies. This study conducted a randomized controlled trial to compare traditional and novel treatment methods in a cohort of 60 insomnia pat
Externí odkaz:
https://doaj.org/article/18f97db2c75e40bfa44509622e629168