Zobrazeno 1 - 10
of 37
pro vyhledávání: '"TARCISIO BRIGNOLI"'
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Staphylococcus aureus produces a plethora of virulence factors critical to its ability to establish an infection and cause disease. We have previously characterized a small membrane protein, MspA, which has pleiotropic effects on virulence a
Externí odkaz:
https://doaj.org/article/474c5d683181416fa8ca93d3e45e0e6b
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/d12a9e9374fb4c3b9854366ac169e8b4
Autor:
Edward JA Douglas, Nathanael Palk, Tarcisio Brignoli, Dina Altwiley, Marcia Boura, Maisem Laabei, Mario Recker, Gordon YC Cheung, Ryan Liu, Roger C Hsieh, Michael Otto, Eoin O'Brien, Rachel M McLoughlin, Ruth C Massey
Publikováno v:
eLife, Vol 12 (2023)
The bloodstream represents a hostile environment that bacteria must overcome to cause bacteraemia. To understand how the major human pathogen Staphylococcus aureus manages this we have utilised a functional genomics approach to identify a number of n
Externí odkaz:
https://doaj.org/article/cdc03cf522bf4fe480f332e52fd5fd2c
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Hundreds of different species of small RNAs can populate a bacterial cell. This small transcriptome contains important information for the adaptation of cellular physiology to environmental changes. Underlying cellular networks involving small RNAs a
Externí odkaz:
https://doaj.org/article/5f7d5ad2c2b142d1943c29bfe5922d41
Autor:
Silvia Santoro, Costanza Paganin, Sara Gilardi, Tarcisio Brignoli, Giovanni Bertoni, Silvia Ferrara
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Behind the pathogenic lifestyle of Pseudomonas aeruginosa exists a complex regulatory network of intertwined switches at both the transcriptional and posttranscriptional levels. Major players that mediate translation regulation of several ge
Externí odkaz:
https://doaj.org/article/3a4663a85d114ff5b0b9ade2e3b195df
Autor:
Andreas F. Haag, Lassi Liljeroos, Paolo Donato, Clarissa Pozzi, Tarcisio Brignoli, Matthew J. Bottomley, Fabio Bagnoli, Isabel Delany
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Staphylococcus aureus is a clinically important bacterial pathogen that has become resistant to treatment with most routinely used antibiotics. Alternative strategies, such as vaccination and phage therapy, are therefore actively being inves
Externí odkaz:
https://doaj.org/article/578569a62c2345048e7ca741aac43fe0
Autor:
Tarcisio Brignoli, Edward Douglas, Seána Duggan, Olayemi Grace Fagunloye, Rajan Adhikari, M. Javad Aman, Ruth C. Massey
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT A major feature of the pathogenicity of Staphylococcus aureus is its ability to secrete cytolytic toxins. This process involves the translocation of the toxins from the cytoplasm through the bacterial membrane and the cell wall to the extern
Externí odkaz:
https://doaj.org/article/42777fa10e2d4ec1ba1fadeec16444b3
Autor:
Marco Spinsanti, Tarcisio Brignoli, Margherita Bodini, Lucia Eleonora Fontana, Matteo De Chiara, Alessia Biolchi, Alessandro Muzzi, Vincenzo Scarlato, Isabel Delany
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009461 (2021)
Neisseria meningitidis is a strictly human pathogen and is the major cause of septicemia and meningitis worldwide. Factor H binding protein (fHbp) is a meningococcal surface-exposed lipoprotein that binds the human Complement factor H allowing the ba
Externí odkaz:
https://doaj.org/article/a35220af77a641d9b4583314beecc598
Autor:
Michaela Gregorova, Daniel Morse, Tarcisio Brignoli, Joseph Steventon, Fergus Hamilton, Mahableshwar Albur, David Arnold, Matthew Thomas, Alice Halliday, Holly Baum, Christopher Rice, Matthew B Avison, Andrew D Davidson, Marianna Santopaolo, Elizabeth Oliver, Anu Goenka, Adam Finn, Linda Wooldridge, Borko Amulic, Rosemary J Boyton, Daniel M Altmann, David K Butler, Claire McMurray, Joanna Stockton, Sam Nicholls, Charles Cooper, Nicholas Loman, Michael J Cox, Laura Rivino, Ruth C Massey
Publikováno v:
eLife, Vol 9 (2020)
Here, we describe the case of a COVID-19 patient who developed recurring ventilator-associated pneumonia caused by Pseudomonas aeruginosa that acquired increasing levels of antimicrobial resistance (AMR) in response to treatment. Metagenomic analysis
Externí odkaz:
https://doaj.org/article/80d0b79d831147a8857f8e7ec24cafa9
Autor:
Sara Borghi, Ana Antunes, Andreas F. Haag, Marco Spinsanti, Tarcisio Brignoli, Enea Ndoni, Vincenzo Scarlato, Isabel Delany
Publikováno v:
Microorganisms, Vol 10, Iss 4, p 834 (2022)
Neisseria meningitidis colonizes the nasopharynx of humans, and pathogenic strains can disseminate into the bloodstream, causing septicemia and meningitis. NHBA is a surface-exposed lipoprotein expressed by all N. meningitidis strains in different is
Externí odkaz:
https://doaj.org/article/d760a7ebf7874d6bae2f17f2238f6ae0