Fibronectin fragments generated by pancreatic trypsin act as endogenous inhibitors of pancreatic tumor growth.

Autor: Resovi A; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Persichitti P; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Brunelli L; Department of Environmental Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Minoli L; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Borsotti P; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Garattini G; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Tironi M; Department of Biomedical Engineering, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Dugnani E; Diabetes Research Institute, IRCCS Ospedale San Raffaele, Milano, Italy., Redegalli M; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., De Simone G; Department of Environmental Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Pastorelli R; Department of Environmental Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Bani MR; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Piemonti L; Diabetes Research Institute, IRCCS Ospedale San Raffaele, Milano, Italy., Mosher DF; Departments of Biomolecular Chemistry and Medicine, University of Wisconsin, Madison, WI, USA., Giavazzi R; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Taraboletti G; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy., Belotti D; Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo and Milan, Italy. dorina.belotti@marionegri.it.

Publikováno v: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Aug 09; Vol. 42 (1), pp. 201. Date of Electronic Publication: 2023 Aug 09.

Controlled extracellular proteolysis of thrombospondins.

Autor: Carminati L; Laboratory of Tumor Microenvironment, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Stezzano 87, 24126 Bergamo, Italy., Carlessi E; Laboratory of Tumor Microenvironment, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Stezzano 87, 24126 Bergamo, Italy., Longhi E; Laboratory of Tumor Microenvironment, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Stezzano 87, 24126 Bergamo, Italy., Taraboletti G; Laboratory of Tumor Microenvironment, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Stezzano 87, 24126 Bergamo, Italy. Electronic address: giulia.taraboletti@marionegri.it.

Publikováno v: Matrix biology : journal of the International Society for Matrix Biology [Matrix Biol] 2023 May; Vol. 119, pp. 82-100. Date of Electronic Publication: 2023 Mar 30.

Inhibition of FGFR Signaling by Targeting FGF/FGFR Extracellular Interactions: Towards the Comprehension of the Molecular Mechanism through NMR Approaches.

Autor: Pagano K; Istituto di Scienze e Tecnologie Chimiche 'Giulio Natta' (SCITEC), via Corti 12, 20133 Milano, Italy., Longhi E; Laboratory of Tumour Microenvironment, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 24126 Bergamo, Italy., Molinari H; Istituto di Scienze e Tecnologie Chimiche 'Giulio Natta' (SCITEC), via Corti 12, 20133 Milano, Italy., Taraboletti G; Laboratory of Tumour Microenvironment, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 24126 Bergamo, Italy., Ragona L; Istituto di Scienze e Tecnologie Chimiche 'Giulio Natta' (SCITEC), via Corti 12, 20133 Milano, Italy.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Sep 17; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 17.

Expression levels of vascular endothelial growth factor, matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases 1 and 2 in the plasma of patients with ovarian carcinoma

Autor: Manenti, L ^a, Paganoni, P ^a, Floriani, I ^b, Landoni, F ^c, Torri, V ^b, Buda, A ^c, Taraboletti, G ^a, Labianca, R ^d, Belotti, D ^a, Giavazzi, R ^{a, ∗}

Publikováno v: In European Journal of Cancer September 2003 39(13):1948-1956

PO-76 The T3R domain of thrombospondin-1 delays tumor growth and improves tumor response to chemotherapy by remodeling the tumor vasculature

Autor: Pinessi, D., Resovi, A., Morosi, L., Borsotti, P., Berndt, A., Giavazzi, R., Zucchetti, M., Taraboletti, G.

Publikováno v: In Thrombosis Research April 2021 200 Supplement 1:S58-S59