Zobrazeno 1 - 10
of 14
pro vyhledávání: '"TAP, transporter associated with antigen processing"'
Autor:
Goshi Shiota, Hiroyuki Tsuchiya
Publikováno v:
Tsuchiya, Hiroyuki. Shiota, Goshi. Immune evasion by cancer stem cells. Regenerative Therapy. 17. 20-33. doi:10.1016/j.reth.2021.02.006
Regenerative Therapy, Vol 17, Iss, Pp 20-33 (2021)
Regenerative Therapy
Regenerative Therapy, Vol 17, Iss, Pp 20-33 (2021)
Regenerative Therapy
Tumor immunity represents a new avenue for cancer therapy. Immune checkpoint inhibitors have successfully improved outcomes in several tumor types. In addition, currently, immune cell-based therapy is also attracting significant attention. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6054a82a446a6f8b0b1100401e59a6
https://doi.org/10.1016/j.reth.2021.02.006
https://doi.org/10.1016/j.reth.2021.02.006
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 315-329 (2021)
Computational and Structural Biotechnology Journal, 19
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 315-329 (2021)
Computational and Structural Biotechnology Journal, 19
Biotherapeutics, and antimicrobial proteins in particular, are of increasing interest for human medicine. An important challenge in the development of such therapeutics is their potential immunogenicity, which can induce production of anti-drug-antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc6eb34d6710e1da9ae4b3df006a799
https://doi.org/10.1016/j.csbj.2020.12.024
https://doi.org/10.1016/j.csbj.2020.12.024
Autor:
Ishtiaque Ahammad, Samia Sultana Lira
Publikováno v:
International Journal of Biological Macromolecules
SARS-CoV-2 is the deadly virus behind COVID-19, the disease that went on to ravage the world and caused the biggest pandemic 21st century has witnessed so far. On the face of ongoing death and destruction, the urgent need for the discovery of a vacci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352a07660711c1227db925386eb3a8b5
https://doi.org/10.1016/j.ijbiomac.2020.06.213
https://doi.org/10.1016/j.ijbiomac.2020.06.213
Autor:
Lélia Delamarre, Christopher M. Rose, Craig Blanchette, Martine Darwish, Romain Bouziat, Jennie R. Lill, Samuel B. Pollock
Publikováno v:
Molecular & Cellular Proteomics : MCP
Advances in several key technologies, including MHC peptidomics, have helped fuel our understanding of basic immune regulatory mechanisms and the identification of T cell receptor targets for the development of immunotherapeutics. Isolating and accur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947ac153e25533f2a43cef70c902c68f
https://pubmed.ncbi.nlm.nih.gov/34129938
https://pubmed.ncbi.nlm.nih.gov/34129938
Publikováno v:
Human Immunology
Given the highly polymorphic nature of Human Leukocyte Antigen (HLA) molecules, it is not surprising that they function as key regulators of the host immune response to almost all invading pathogens, including SARS-CoV-2, the etiological agent respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::51bc5413b4c2d797c3cdef74cf69940d
https://pubmed.ncbi.nlm.nih.gov/34116863
https://pubmed.ncbi.nlm.nih.gov/34116863
Autor:
Michal Bassani-Sternberg, Elise Ramia, Brian Stevenson, Greta Forlani, Elodie Lauret Marie Joseph, Michael Linnebacher, Roberto S. Accolla, Florian Huber, HuiSong Pak, Justine Michaux
Publikováno v:
Molecular & Cellular Proteomics : MCP
Molecular & cellular proteomics, vol. 20, pp. 100032
Molecular & cellular proteomics, vol. 20, pp. 100032
CD4+ T cell responses are crucial for inducing and maintaining effective anticancer immunity, and the identification of human leukocyte antigen class II (HLA-II) cancer-specific epitopes is key to the development of potent cancer immunotherapies. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcddca7fc19ba47138689bfadc4b41e
http://hdl.handle.net/11383/2103085
http://hdl.handle.net/11383/2103085
Autor:
Yue Qi, Mohammad Haghir Ebrahimabadi, Khoa D. Nguyen, Shaojian Gao, Tapan K. Maity, Xu Zhang, Vikram Misra, Udayan Guha, Javed Khan, Constance M. Cultraro, Cenk Sahinalp, David Milewski, Catherine Ade, Ken-ichi Hanada, James Chih-Hsin Yang
Publikováno v:
Molecular & Cellular Proteomics : MCP
Immune checkpoint inhibitors and adoptive lymphocyte transfer–based therapies have shown great therapeutic potential in cancers with high tumor mutational burden (TMB), such as melanoma, but not in cancers with low TMB, such as mutant epidermal gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a512a9af5db7e9b56f4226206fd2ec
https://doi.org/10.1016/j.mcpro.2021.100136
https://doi.org/10.1016/j.mcpro.2021.100136
Publikováno v:
Molecular & Cellular Proteomics : MCP
A subset of class I major histocompatibility complex (MHC)-bound peptides is produced from immature proteins that are rapidly degraded after synthesis. These defective ribosomal products (DRiPs) have been implicated in early alert of the immune syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb35f062c8a03903b8b77f6f0486f96f
https://doi.org/10.1016/j.mcpro.2021.100105
https://doi.org/10.1016/j.mcpro.2021.100105
Autor:
Andrea D. Lipińska, Małgorzata Graul, Magdalena J. Ślusarz, Sylwia Rodziewicz-Motowidło, Emilia Sikorska, Igor Zhukov, Franciszek Kasprzykowski, Natalia Karska
Publikováno v:
Biochimica et Biophysica Acta. Biomembranes
The transporter associated with antigen processing (TAP) directly participates in the immune response as a key component of the cytosolic peptide to major histocompatibility complex (MHC) class I protein loading machinery. This makes TAP an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a1cd809be405f2e3e8ac485b4b34c9
https://pubmed.ncbi.nlm.nih.gov/30772281
https://pubmed.ncbi.nlm.nih.gov/30772281
Publikováno v:
Advances in Cancer Research
Interferons represent a protein family with pleiotropic functions including immunomodulatory, cytostatic, and cytotoxic activities. Based on these effects, interferons are involved in innate as well as adaptive immunity, thereby shaping the tumor hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c70612228c3b4904368125b7037c233
https://pubmed.ncbi.nlm.nih.gov/19055946
https://pubmed.ncbi.nlm.nih.gov/19055946