Zobrazeno 1 - 10
of 2 249
pro vyhledávání: '"TAMs"'
Autor:
Martyna Stachowicz-Suhs, Natalia Łabędź, Magdalena Milczarek, Dagmara Kłopotowska, Beata Filip-Psurska, Adam Maciejczyk, Rafał Matkowski, Joanna Wietrzyk
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-23 (2024)
Abstract Vitamin D3 (VD) is known for its immunomodulatory and anticancer effects. This study aimed to characterize tumor-associated macrophages (TAMs) in breast cancer (BC) and assess the influence of VD and its active metabolite, calcitriol, on the
Externí odkaz:
https://doaj.org/article/223fb776c35e4eea837e283d9b35a21d
Autor:
Zhe Zhang, Yao Xiao, Siyi Zhao, Jun Liu, Jie Zeng, Feng Xiao, Bin Liao, Xuesong Shan, Hong Zhu, Hua Guo
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Family with sequence similarity 109, member B (FAM109B) is involved in endocytic transport and affects genetic variation in brain methylation. It is one of the important genes related to immune cell-associated diseases. In the tum
Externí odkaz:
https://doaj.org/article/2b6a81e3ffa04a5892e57ead678f5717
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-19 (2024)
Abstract Background The internal heterogeneity of breast cancer, notably the tumor microenvironment (TME) consisting of malignant and non-malignant cells, has been extensively explored in recent years. The cells in this complex cellular ecosystem act
Externí odkaz:
https://doaj.org/article/17c7448b694a4fa5bf6ea6a2e831c042
Autor:
Wei Gu, Wen Guo, Zhishuang Ren, Yimeng Zhang, Meiqi Han, Qinfu Zhao, Yikun Gao, Yuling Mao, Siling Wang
Publikováno v:
Bioactive Materials, Vol 38, Iss , Pp 472-485 (2024)
Reactive oxygen species (ROS) generated from photosensitizers exhibit great potential for repolarizing immunosuppressive tumor-associated macrophages (TAMs) toward the anti-tumor M1 phenotype, representing a promising cancer immunotherapy strategy. N
Externí odkaz:
https://doaj.org/article/9b07c8b7a8374b929715108f70a14837
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background M2-like tumor-associated macrophages (M2-like TAMs) play key roles in tumor progression and the immune response. However, the clinical significance and prognostic value of M2-like TAMs-associated regulatory genes in gastric cancer
Externí odkaz:
https://doaj.org/article/6453dc7515a64048b51aa045ee70ebab
Autor:
Peng Sun, Zhenfeng Li, Zaojun Yan, Zhaofeng Wang, Peng Zheng, Mingliang Wang, Xu Chang, Zihao Liu, Jianxin Zhang, Huiyong Wu, Wenbo Shao, Dewen Xue, Jinming Yu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Lenvatinib, a multitarget kinase inhibitor, has been proven to be effective in the treatment of advanced hepatocellular carcinoma. It has been previously demonstrated that tumour associated macrophages (TAMs) in tumour tissues can promote HC
Externí odkaz:
https://doaj.org/article/2101331b2a6b4a46b73885fae0b36a05
Publikováno v:
Медицинская иммунология, Vol 26, Iss 4, Pp 693-700 (2024)
Tumor-associated macrophages (TAMs) are an important and most represented population of immune cells in the tumor microenvironment. To a great extent, TAMs can determine the direction of the antitumor immune response; they can either additionally sti
Externí odkaz:
https://doaj.org/article/f40a5d35cae14020b618e85242676dbb
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-24 (2024)
Abstract Tumor-associated macrophages (TAMs) are pivotal in cancer progression, influencing tumor growth, angiogenesis, and immune evasion. This review explores the spatial and temporal heterogeneity of TAMs within the tumor microenvironment (TME), h
Externí odkaz:
https://doaj.org/article/d1f98eb6fcff4d46bd52d7696aad735d
Autor:
Fan Guo, Weina Kong, Dewei Li, Gang Zhao, Miyessar Anwar, Feifei Xia, Yuanming Zhang, Cailing Ma, Xiumin Ma
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-19 (2024)
Abstract Background and purpose PD-1/PD-L1 inhibitors have become a promising therapy. However, the response rate is lower than 30% in patients with cervical cancer (CC), which is related to immunosuppressive components in tumor microenvironment (TME
Externí odkaz:
https://doaj.org/article/29645eaa7b054ce9acb617740adc04c8
Autor:
Ana Sami, Afsheen Raza
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Breast cancer has the highest global incidence among all cancers, affecting more than 2 million individuals annually. Despite the availability of new drugs and novel treatment combinations, it is postulated that the incidence and mortality of breast
Externí odkaz:
https://doaj.org/article/c13555746f324d95bce5cc5e85384fc9