Zobrazeno 1 - 10
of 159
pro vyhledávání: '"TAMOTSU KIYOSHIMA"'
Autor:
Yuka Miyahara, Hu Chen, Masafumi Moriyama, Keita Mochizuki, Naoki Kaneko, A. S. M. Rafiul Haque, Akira Chinju, Kazuki Kai, Mizuki Sakamoto, Noriko Kakizoe-Ishiguro, Masaki Yamauchi, Kenichi Ogata, Tamotsu Kiyoshima, Shintaro Kawano, Seiji Nakamura
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Oral lichen planus (OLP) is a chronic inflammatory disease associated with T cell infiltration. The crosstalk between oral epithelium and mucosal T cells was considered to be crucial in the pathogenesis of OLP. Here, we selectively extracted
Externí odkaz:
https://doaj.org/article/935a8d70adfb45f1bd3704f276984210
Autor:
Hu Chen, Junsei Sameshima, Shiho Yokomizo, Tomoki Sueyoshi, Haruki Nagano, Yuka Miyahara, Taiki Sakamoto, Shinsuke Fujii, Tamotsu Kiyoshima, Thomas Guy, Seiji Nakamura, Masafumi Moriyama, Naoki Kaneko, Shintaro Kawano
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCancer immunotherapy targeting CD8+ T cells has made remarkable progress, even for oral squamous cell carcinoma (OSCC), a heterogeneous epithelial tumor without a substantial increase in the overall survival rate over the past decade. Howev
Externí odkaz:
https://doaj.org/article/6dfcb4d452f74bcb92b69749c60068b3
Autor:
Jing Gao, Aonan Li, Shinsuke Fujii, Fei Huang, Chihiro Nakatomi, Ichiro Nakamura, Hiroaki Honda, Tamotsu Kiyoshima, Eijiro Jimi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Salivary glands develop through epithelial-mesenchymal interactions and are formed through repeated branching. The Crk-associated substrate protein (p130Cas) serves as an adapter that forms a complex with various proteins via integrin and gr
Externí odkaz:
https://doaj.org/article/3b9c579796604763af9a6bb39bc0a114
Autor:
Daigaku Hasegawa, Kana Hasegawa, Hiroshi Kaneko, Shinichiro Yoshida, Hiromi Mitarai, Mai Arima, Atsushi Tomokiyo, Sayuri Hamano, Hideki Sugii, Naohisa Wada, Tamotsu Kiyoshima, Hidefumi Maeda
Publikováno v:
Stem Cells International, Vol 2020 (2020)
Periodontal ligament (PDL) stem cells (PDLSCs) have been reported as a useful cell source for periodontal tissue regeneration. However, one of the issues is the difficulty of obtaining a sufficient number of PDLSCs for clinical application because ve
Externí odkaz:
https://doaj.org/article/39551639219d4e94b8c0aa9ac7afebc5
Autor:
Keigo Kubota, Masafumi Moriyama, Sachiko Furukawa, Haque A. S. M. Rafiul, Yasuyuki Maruse, Teppei Jinno, Akihiko Tanaka, Miho Ohta, Noriko Ishiguro, Masaaki Yamauchi, Mizuki Sakamoto, Takashi Maehara, Jun-Nosuke Hayashida, Shintaro Kawano, Tamotsu Kiyoshima, Seiji Nakamura
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Tumor-associated macrophages (TAMs) promote cancer cell proliferation, invasion, and metastasis by producing various mediators. Although preclinical studies demonstrated that TAMs preferentially express CD163 and CD204, the TAM subsets in or
Externí odkaz:
https://doaj.org/article/5eb629ab63b04451ae6df8ef9aa312e4
Autor:
Tamotsu Kiyoshima, Hiroaki Fujiwara, Kengo Nagata, Hiroko Wada, Yukiko F. Ookuma, Maho Shiotsuka, Makiko Kihara, Kana Hasegawa, Hirotaka Someya, Hidetaka Sakai
Publikováno v:
Stem Cell Research, Vol 12, Iss 1, Pp 309-322 (2014)
Previous studies have shown that the recombination of cells liberated from developing tooth germs develop into teeth. However, it is difficult to use human developing tooth germ as a source of cells because of ethical issues. Previous studies have re
Externí odkaz:
https://doaj.org/article/3d7c0455cfb544f5b866e708a253e598
Autor:
Makiko Kihara, Tamotsu Kiyoshima, Kengo Nagata, Hiroko Wada, Hiroaki Fujiwara, Kana Hasegawa, Hirotaka Someya, Ichiro Takahashi, Hidetaka Sakai
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103928 (2014)
Itm2a is a type II transmembrane protein with a BRICHOS domain. We investigated the temporospatial mRNA and protein expression patterns of Itm2a in the developing lower first molar, and examined the subcellular localization of Itm2a in murine dental
Externí odkaz:
https://doaj.org/article/d0132b27a0104350a94944539aea4c9a
Autor:
Tamotsu Kiyoshima, Hisato Yoshida, Hiroko Wada, Kengo Nagata, Hiroaki Fujiwara, Makiko Kihara, Kana Hasegawa, Hirotaka Someya, Hidetaka Sakai
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80998 (2013)
V-ATPase is involved in the acidification of the microenvironment around/in solid tumors, such as oral squamous cell carcinoma (OSCC). V-ATPase is thought to induce tumor invasion and multi-drug resistance in several malignant tumors, and it also con
Externí odkaz:
https://doaj.org/article/863fba8260f14c5abf0aefe2fddc6c07
Autor:
Ikumi Imajo, Tomohiro Yamada, Takahiro Fujinaga, Koki Nagano, Wataru Kumamaru, Yuta Yanai, Toru Chikui, Tamotsu Kiyoshima
Publikováno v:
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 35:445-449
Autor:
Koki Nagano, Tomohiro Yamada, Kotaro Ishii, Takahiro Fujinaga, Minami Shibuya, Yuta Yanai, Tamotsu Kiyoshima, Yoshihide Mori
Publikováno v:
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 34:536-541