Zobrazeno 1 - 10
of 623
pro vyhledávání: '"TAM receptors"'
Autor:
Chuanyu Luo, Mengyuan Li, Peiyu Bian, Jiali Yang, Xiamei Liao, Yangchao Dong, Chuantao Ye, Fanglin Zhang, Xin Lv, Qianqian Zhang, Yingfeng Lei
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Japanese encephalitis is an acute infectious disease of the central nervous system caused by neurotropic Japanese encephalitis virus (JEV). As a member of TAM (Tyro3, Axl and Mertk) family, Mertk has involved in multiple biological processes
Externí odkaz:
https://doaj.org/article/2069fd4b1533448b84c135c2f2b54467
Autor:
Daria Apostolo, Davide D’Onghia, Alessandra Nerviani, Giulia Maria Ghirardi, Daniele Sola, Mattia Perazzi, Stelvio Tonello, Donato Colangelo, Pier Paolo Sainaghi, Mattia Bellan
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 7486-7504 (2024)
Systemic sclerosis (SSc) is a connective tissue disorder characterized by microvascular injury, extracellular matrix deposition, autoimmunity, inflammation, and fibrosis. The clinical complexity and high heterogeneity of the disease make the discover
Externí odkaz:
https://doaj.org/article/b145d3b6478745a084f49f158c0485a4
Autor:
Aurélie Joussaume, Chryso Kanthou, Olivier E. Pardo, Lucie Karayan-Tapon, Omar Benzakour, Fatima Dkhissi
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 4, Pp 3278-3293 (2024)
Protein S (PROS1) is a vitamin K-dependent anticoagulant factor, which also acts as an agonist for the TYRO3, AXL, and MERTK (TAM) tyrosine kinase receptors. PROS1 is produced by the endothelium which also expresses TAM receptors, but little is known
Externí odkaz:
https://doaj.org/article/7eb8813ce6a24d078a0b98f358bbfe47
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105278- (2024)
Summary: Pancreatic ductal adenocarcinoma (PDAC) represents the most prevalent type of pancreatic cancer and ranks among the most aggressive tumours, with a 5-year survival rate of less than 11%. Projections indicate that by 2030, it will become the
Externí odkaz:
https://doaj.org/article/a76221a8f78648a18aa25d83616d0152
Autor:
Sturla Magnus Grøndal, Anna Tutusaus, Loreto Boix, Maria Reig, Magnus Blø, Linn Hodneland, Gro Gausdal, Akil Jackson, Pablo Garcia de Frutos, James Bradley Lorens, Albert Morales, Montserrat Marí
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Background and aimsMetabolic dysfunction-associated steatohepatitis (MASH) is a significant health concern with limited treatment options. AXL, a receptor tyrosine kinase activated by the GAS6 ligand, promotes MASH through activation of hepatic stell
Externí odkaz:
https://doaj.org/article/6052153a12c545f1be1327af8224916c
Autor:
Davide D’Onghia, Donato Colangelo, Mattia Bellan, Stelvio Tonello, Chiara Puricelli, Eleonora Virgilio, Daria Apostolo, Rosalba Minisini, Luciana L. Ferreira, Leonardo Sozzi, Federica Vincenzi, Roberto Cantello, Cristoforo Comi, Mario Pirisi, Domizia Vecchio, Pier Paolo Sainaghi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe protein growth arrest-specific 6 (Gas6) and its tyrosine kinase receptors Tyro-3, Axl, and Mer (TAM) are ubiquitous proteins involved in regulating inflammation and apoptotic body clearance. Multiple sclerosis (MS) is the most common
Externí odkaz:
https://doaj.org/article/3fff0f74012f4f5bbb7d2ea7cef3b413
Akademický článek
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Akademický článek
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Autor:
Oltin-Tiberiu Pop, Anne Geng, Emilio Flint, Arjuna Singanayagam, Caner Ercan, Lucia Possamai, Vishal C. Patel, Patrizia Kuenzler, Marie-Anne Meier, Savas Soysal, Petr Hruz, Otto Kollmar, Kate C. Tatham, Josie K. Ward, Beat Müllhaupt, Achim Weber, Julia Wendon, Jan Hendrik Niess, Markus Heim, David Semela, Christopher Weston, Charalambos G. Antoniades, Luigi Maria Terracciano, Evangelos Triantafyllou, Robert G. Brenig, Christine Bernsmeier
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 1, Pp 17-37 (2023)
Background & Aims: AXL and MERTK expression on circulating monocytes modulated immune responses in patients with cirrhosis (CD14+HLA-DR+AXL+) and acute-on-chronic liver failure (CD14+MERTK+). AXL expression involved enhanced efferocytosis, sustained
Externí odkaz:
https://doaj.org/article/e232e5d8368941d4a69e17e66c9c9998
Autor:
Varsha Gadiyar, Gopi Patel, Jesse Chen, Dominico Vigil, Nan Ji, Veronica Campbell, Kirti Sharma, Yatao Shi, Matthew M. Weiss, Raymond B. Birge, Viralkumar Davra
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
TAM receptors (TYRO3, AXL, and MERTK) comprise a family of homologous receptor tyrosine kinases (RTK) that are expressed across a range of liquid and solid tumors where they contribute to both oncogenic signaling to promote tumor proliferation and su
Externí odkaz:
https://doaj.org/article/388b5ce7ffc844c99da2b49db324d5dc