Výsledky vyhledávání - "TAKENARI NAKAGOME"

Studies on quinoline derivatives and related compounds. III. A novel pyridine synthesis to give substituted 1,4-dihydro-4-oxonicotinic acids

Autor: Hideo Agui, Hisao Tobiki, Takenari Nakagome

Publikováno v: Journal of Heterocyclic Chemistry. 12:1245-1254

A variety of 5-mono- and 5,6-disubstituted 1,4-dihydro-4-oxonicotinates were prepared by a novel pyridine synthesis which involves thermal cyclisation of enaminomethylenemalonates 9. The intermediates 9 were readily prepared through a few steps from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d440ce991653805d39539c71d8869528
https://doi.org/10.1002/jhet.5570120629

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Studies on β-Lactam Antibiotics. V. Synthesis of 6-[D (-)-α-(Acylamino)-4-hydroxyphenylacetamido] penicillanic Acids and Antibacterial Activity

Autor: Hiroshi Noguchi, Yasuko Eda, Iwao Nakatsuka, Hisao Tobiki, Toshiaki Komatsu, H. Yamada, Takenari Nakagome, Kozo Shimago

Publikováno v: YAKUGAKU ZASSHI. 100:133-139

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3978caa0501cc524eb4cf7cb5f32a66
https://doi.org/10.1248/yakushi1947.100.2_133

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Conversion of acylamidopenicillins to phosphoramidopenicillins, and removal of their phosphoryl side chain

Autor: Masataka Fukumura, Takenari Nakagome, Noritaka Hamma

Publikováno v: Chemical and Pharmaceutical Bulletin. 24:3058-3064

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d5a94176f7069a69d4c06c9575a56a
https://doi.org/10.1248/cpb.24.3058

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Studies on quinoline derivatives and related compounds. II. Synthesis of 5-substituted 1-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Autor: Toshiaki Komatsu, Hideo Agui, Takenari Nakagome

Publikováno v: Journal of Heterocyclic Chemistry. 12:557-563

The cyclization of m-substituted anilinomethylenemalonates (1) in the presence of polyphosphate ester and some other cyclizing agents gave mixtures of the isomeric ethyl 5- (2) and 7-substituted 4-hydroxy-3-quinolinecarboxylates (3), which led to mix

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::35d4cc1b26f6aacbcbc07fc4d847ca10
https://doi.org/10.1002/jhet.5570120324

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Antibacterial activity of miloxacin

Autor: Takenari Nakagome, Toshiaki Komatsu, Akio Izawa, Y Kisaki, Yasuko Eda, K Irie

Publikováno v: Antimicrobial Agents and Chemotherapy. 18:37-40

The chemotherapeutic properties of miloxacin (5,8-dihydro-5-methoxy-8-oxo-2H-1,3-dioxolo-[4,5-g]quinoline-7-carboxylic acid) have been compared with those of oxolinic acid and nalidixic acid. The in vitro activities of miloxacin (minimum inhibitory c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce933e2ad76db1fb1a00e76ac93b4355
https://doi.org/10.1128/aac.18.1.37

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Epimerization of penicillin sulfoxides and their conversion to isothiazolones. Dual pathway on treatment with bases

Autor: Takenari Nakagome, Masataka Fukumura, Noritaka Hamma

Publikováno v: Tetrahedron Letters. 16:4123-4126

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44e86519fab60e8420bd43253cf7d445
https://doi.org/10.1016/s0040-4039(00)91191-2

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Studies on quinoline derivatives and related compounds. VI. A novel displacement reaction of 1-ethylquinolinium iodides with nucleophiles

Autor: Takenari Nakagome, Hideo Agui

Publikováno v: Journal of Heterocyclic Chemistry. 16:1353-1360

The reaction of 4-amino- (3a) and 4-anilino-3-carbethoxy-1-ethyl-6,7-methylenedioxy-quinolinium iodide (3b) with nucleophilic reagents produced 7-substituted 4-amino-3-carboxy-1-ethyl-6-hydroxyquinolinium betaines (5b-d) and 7-substituted 1-ethyl-1,4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c83ce2aa13e1ac90a270b1b806bbd75b
https://doi.org/10.1002/jhet.5570160713

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