Zobrazeno 1 - 10
of 46
pro vyhledávání: '"TAKAYUKI NAKASHIMA"'
Autor:
Hiromi Sasaki, Satoshi Nagano, Hirofumi Shimada, Takayuki Nakashima, Masahiro Yokouchi, Yasuhiro Ishidou, Takao Setoguchi, Setsuro Komiya
Publikováno v:
Journal of Orthopaedic Surgery, Vol 25 (2017)
Intraosseous epidermoid cysts are exceedingly rare. Known as pseudotumors, not true neoplasms, intraosseous epidermoid cysts usually involve the phalanges, the skull, and the toes. Intraosseous epidermoid cysts typically present as destructive osteol
Externí odkaz:
https://doaj.org/article/e02e870b95464cdc85040b43052a510f
Publikováno v:
Molecules, Vol 21, Iss 9, p 1173 (2016)
Aromatic groups were incorporated into 9H-9-silafluorene units at the 9-position (mono-9H-silafluorenes) and 9,9′-positions (di-9H-9-silafluorenes). The aryl substituents showed weak conjugation to the 9H-9-silafluorene for 9-aryl substituted ones
Externí odkaz:
https://doaj.org/article/2a7aa75288c54c228256e1c32faffdbc
Autor:
Yukimasa Shiotsu, Shiro Soga, Shiro Akinaga, Yutaka Kanda, Hiroshi Nakagawa, Toshihiro Seike, Hisashi Tagaya, Toshihiko Ishii, Takayuki Nakashima
Supplementary Data from New Molecular and Biological Mechanism of Antitumor Activities of KW-2478, a Novel Nonansamycin Heat Shock Protein 90 Inhibitor, in Multiple Myeloma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05eac44feed9bb3a0c2e4e510ae4018f
https://doi.org/10.1158/1078-0432.22442663
https://doi.org/10.1158/1078-0432.22442663
Autor:
Yukimasa Shiotsu, Shiro Soga, Shiro Akinaga, Yutaka Kanda, Hiroshi Nakagawa, Toshihiro Seike, Hisashi Tagaya, Toshihiko Ishii, Takayuki Nakashima
Purpose: The heat shock protein 90 (Hsp90) plays an important role in chaperoning oncogenic client proteins in multiple myeloma (MM) cells, and several Hsp90 inhibitors have shown antitumor activities both in vitro and in vivo. However the precise me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b9b7f93cb765894d34df7b7b1e20ec
https://doi.org/10.1158/1078-0432.c.6519338
https://doi.org/10.1158/1078-0432.c.6519338
Autor:
Shigeru Akaiwa, Koji Miyagawa, Takayuki Nakashima, Tatsuya Sakoda, Takuma Miyake, Akira Takayama
Publikováno v:
2022 9th International Conference on Condition Monitoring and Diagnosis (CMD).
Publikováno v:
Japanese Journal of Oral Diagnosis / Oral Medicine. 34:242-246
Publikováno v:
International Journal of Clinical Oncology
DEK is a highly conserved nuclear factor that plays an important role in the regulation of multiple cellular processes.DEKwas discovered to be an oncogene as a fusion withNUP214gene, which results in producing DEK-NUP214 proteins, in a subset of pati
Autor:
Kazuo Kubo, Takayuki Nakashima, Kaori Yagi, Katsuya Okawa, Tomoko Hamada, Yoichi Nishiya, Yuichi Matsumoto, Takamichi Imaizumi, Yukino Nosaka, Akiyo Hirose, Naomi Kashima, Daisuke Yamaguchi
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Phenotypic screening in drug discovery has been revived with the expectation of providing promising lead compounds and drug targets and improving the success rate of drug approval. However, target identification remains a major bottleneck in phenotyp
Autor:
Akihiro Hirata, Kazuhisa Ishida, Akira Hara, Takauji Tanaka, Toshiyuki Shibata, Takayuki Nakashima, Hiroyuki Tomita
Publikováno v:
Oral Oncology. 73:16-20
Oral squamous cell carcinoma (OSCC) patients have a low 5-year survival rate and poor prognosis. To improve survival and prognosis, the causes and processes involved in lesion development should be evaluated. For this purpose, the use of OSCC mouse m
Autor:
Takayuki Nakashima, Kazuhiro Kaneko, Takuji Tanaka, Hiroyuki Tomita, Ayumi Niwa, Seiya Kuwano, Akihiro Hirata, Kenji Hisamatsu, Kei Noguchi, Akira Hara, Keita Kimura, Yuichiro Hatano, Tatsuhiko Miyazaki, Tomohiro Kanayama, Yukiya Orihara
Publikováno v:
Oncotarget
// Ayumi Niwa 1, * , Seiya Kuwano 1, * , Hiroyuki Tomita 1 , Keita Kimura 1 , Yukiya Orihara 1 , Tomohiro Kanayama 1 , Kei Noguchi 1 , Kenji Hisamatsu 1 , Takayuki Nakashima 1 , Yuichiro Hatano 1 , Akihiro Hirata 2 , Tatsuhiko Miyazaki 3 , Kazuhiro K