Hokuriku-plus familial hypercholesterolaemia registry study: rationale and study design

Autor: Hiroshi Matsumoto, Akihiro Nomura, Hayato Tada, Hirofumi Okada, Atsushi Nohara, Masa-aki Kawashiri, Koji Maeno, Manabu Fujimoto, Shohei Yoshida, Masaya Shimojima, Toyonobu Tsuda, Mika Mori, Shin-ichiro Takashima, Takeshi Kato, Soichiro Usui, Kenji Sakata, Kenshi Hayashi, Noboru Fujino, Akihiro Inazu, Shizuko Takahara, Yasuhito Imai, Takao Matsubara, Kenji Miwa, Masanobu Namura, Hidenobu Terai, Taiji Yoshida, Tsutomu Araki, Masahiro Minamoto, Toru Aburao, Yuji Ito, Chiaki Nakanishi, Suguru Kawasaki, Yasuhiro Todo, Junji Koizumi, Yoshihito Kita, Hiroaki Shintaku, Akihiko Hodatsu, Hidekazu Ino, Toshinori Higashikata, Mutsuko Takata, Katsushi Misawa, Masato Yamaguchi, Yoshihiro Noji, Kazuo Osato, Tomohito Mabuchi, Taro Ichise, Bunji Kaku, Shoji Katsuda, Katsuharu Uchiyama, Kensuke Fujioka, Takuya Nakahashi, Tsuyoshi Nozue, Ichiro Michishita, Kazuo Usuda, Kanichi Otowa, Kazuyasu Okeie, Satoshi Hirota, Isao Aburadani, Keisuke Kurokawa, Osamu Takatori, Shunichiro Hondo, Hiroyuki Oda, Shigeo Takata, Hisayoshi Murai, Masaki Kinoshita, Hideo Nagai, Yoshiteru Sekiguchi, Satoru Sakagami, Wataru Omi, Chikara Fujita, Tatsuo Katsuki, Hiroshi Ootsuji, Atsushi Igarashi, Manabu Nakano, Seiichiro Okura, Yasuhito Mitamura, Naoki Sugimoto, Masakazu Yamamoto, Hironobu Akao, Kouji Kajinami, Masayuki Takamura

Publikováno v: BMJ Open, Vol 10, Iss 9 (2020)

Introduction Familial hypercholesterolaemia (FH) is an autosomal-dominant inherited genetic disease. It carries an extremely high cardiovascular risk associated with significantly elevated low-density lipoprotein (LDL) cholesterol. The diagnostic rat

Externí odkaz: https://doaj.org/article/917dd099aa3a44eba50203d24f5b2dba

Infiltrative tumor growth patterns on magnetic resonance imaging associated with systemic inflammation and oncological outcome in patients with high-grade soft-tissue sarcoma.

Autor: Tomoki Nakamura, Akihiko Matsumine, Takao Matsubara, Kunihiro Asanuma, Yuki Yada, Tomohito Hagi, Akihiro Sudo

Publikováno v: PLoS ONE, Vol 12, Iss 7, p e0181787 (2017)

The aim of this study was to determine whether the tumor infiltrative growth pattern on magnetic resonance imaging (MRI) was associated with blood inflammatory markers (C-reactive protein; CRP and Neutrophil-lymphocyte ratio; NLR) and survival in pat

Externí odkaz: https://doaj.org/article/c3b7422727ba4062b0ddbcd2cba00b28

Catheter Ablation of Atrial Tachycardia Originating from the Tip of Right Atrial Appendage

Autor: Masaru Inoue, MD, Takao Matsubara, MD, Toshihiko Yasuda, MD, Kenji Miwa, MD, Tadatsugu Gamou, MD, Hounin Kanaya, MD

Publikováno v: Journal of Arrhythmia, Vol 25, Iss 3, Pp 153-157 (2009)

Right atrial appendage tachycardia is not common and can be eliminated by catheter ablation with a high success rate and low recurrence rate. However, the structural properties of the atrial appendage, including blind-ended structure, abundant trabec

Externí odkaz: https://doaj.org/article/da90b034b0d7498592fe859db13a7226

Long-term clinical outcome in patients with high-grade soft tissue sarcoma who were treated with surgical adjuvant therapy using acridine orange after intra-lesional or marginal resection

Autor: Tomohito Hagi, Kunihiro Asanuma, Takao Matsubara, Katsuyuki Kusuzaki, Hiroaki Murata, Akihiro Sudo, Tomoki Nakamura

Publikováno v: Photodiagnosis and Photodynamic Therapy. 23:165-170

Background We investigated the long-term clinical efficacy of acridine orange (AO) therapy on the inhibition of local recurrence after marginal or intra-lesional tumor resection in high-grade soft tissue sarcomas (STSs). Methods Our study consisted o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfdab4796bc0b080dce81bdf4c71600
https://doi.org/10.1016/j.pdpdt.2018.06.001

Natural extracellular nanovesicles and photodynamic molecules: is there a future for drug delivery?

Autor: Rossella Di Raimo, Stefano Fais, Hiroaki Murata, Fabrizio Carta, Katsuyuki Kusuzaki, Claudiu T. Supuran, Mariantonia Logozzi, Elisabetta Iessi, Takao Matsubara

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 908-916 (2017)
Journal of Enzyme Inhibition and Medicinal Chemistry

Photodynamic molecules represent an alternative approach for cancer therapy for their property (i) to be photo-reactive; (ii) to be not-toxic for target cells in absence of light; (iii) to accumulate specifically into tumour tissues; (iv) to be activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3e72486df70c58c9841222f78ca377
https://doaj.org/article/f76dc04949d74e688c0662decc1a6ca6