Zobrazeno 1 - 10
of 1 200
pro vyhledávání: '"TAKAHIRO YAMADA"'
Autor:
Erika Nakajima, Yuko Yokohama, Saori Sugiyama, Mio Taketazu, Kenrokuro Mitsube, Takahiro Yamada, Anna Hammarsjö, Giedre Grigelioniene, Gen Nishimura, Yoshio Makita
Publikováno v:
Human Genome Variation, Vol 11, Iss 1, Pp 1-3 (2024)
Abstract We report a case of a fetus with short-rib thoracic dysplasia (SRTD) with polydactyly that also presented with atypical severe acro-mesomelic ossification defects. Genetic analysis using massively parallel sequencing of a skeletal dysplasia
Externí odkaz:
https://doaj.org/article/d24cdf2acb6a46a0b51a559d8e90efb2
Autor:
Hiroaki Fujita, Taiichi Wakiya, Yota Tatara, Keinosuke Ishido, Yoshiyuki Sakamoto, Norihisa Kimura, Hajime Morohashi, Takuya Miura, Takahiro Muroya, Harue Akasaka, Hiroshi Yokoyama, Taishu Kanda, Shunsuke Kubota, Aika Ichisawa, Kenta Ogasawara, Daisuke Kuwata, Yoshiya Takahashi, Akie Nakamura, Keisuke Yamazaki, Takahiro Yamada, Ryo Matsuyama, Masanobu Kanou, Kei Yamana, Ken Itoh, Kenichi Hakamada
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Nicotinamide adenine dinucleotide (NAD +) plays a pivotal role in numerous cellular functions. Reduced NAD + levels are postulated to be associated with cancer. As interest in understanding NAD + dynamics in cancer patients with therapeutic
Externí odkaz:
https://doaj.org/article/36e1888fc82c4bf1b7f2105e410b61a2
Autor:
Takahiro Shibayama, Akimasa Hayashi, Masao Toki, Keiichiro Kitahama, Yu-Jui Ho, Kenichiro Kato, Takahiro Yamada, Sho Kawamoto, Komei Kambayashi, Kazushige Ochiai, Koichi Gondo, Naohiro Okano, Jerry P. Melchor, Christine A. Iacobuzio-Donahue, Yoshihiro Sakamoto, Tadakazu Hisamatsu, Junji Shibahara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Although sequence-based studies show that basal-like features lead to worse prognosis and chemotherapy-resistance compared to the classical subtype in advanced pancreatic ductal adenocarcinoma (PDAC), a surrogate biomarker distinguishing bet
Externí odkaz:
https://doaj.org/article/62dc4ee5968d4df19cb11b90bf76aca0
Elastoplastic damage analysis with algebraic derivation of consistent tangent by block Newton method
Publikováno v:
Nihon Kikai Gakkai ronbunshu, Vol 90, Iss 936, Pp 24-00081-24-00081 (2024)
The simultaneously iterative procedure proposed by the authors is applied to elastoplastic problems with damage. From the definition of a coupled problem of the weak form of the equilibrium equation and the constraint conditions for plastic yielding
Externí odkaz:
https://doaj.org/article/60cee8a951f7445787f065c7f60c7a8b
Autor:
Yutaro Hara, Hiroki Mizukami, Keisuke Yamazaki, Takahiro Yamada, Akiko Igawa, Yuki Takeuchi, Takanori Sasaki, Hanae Kushibiki, Kotaro Murakami, Kazuhiro Kudoh, Keinosuke Ishido, Kenichi Hakamada
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 5, Pp 354-366 (2023)
Abstract Diabetes mellitus (DM) is a risk factor for pancreatic ductal adenocarcinoma (PDAC) that promotes the promoter methylation of CDH1. It is still unclear whether DM can exert other epigenetic effects, such as altering microRNA (miR) expression
Externí odkaz:
https://doaj.org/article/49220e3a8e094148a1c67db469d803bb
Autor:
Masahiro Iwasaku, Junji Uchino, Kenji Chibana, Shigeru Tanzawa, Takahiro Yamada, Kazunori Tobino, Yasuki Uchida, Takashi Kijima, Katsumi Nakatomi, Miiru Izumi, Nobuyo Tamiya, Hideharu Kimura, Masaki Fujita, Ryoichi Honda, Chieko Takumi, Tadaaki Yamada, Yoshiko Kaneko, Fumiaki Kiyomi, Koichi Takayama
Publikováno v:
Cancer Medicine, Vol 12, Iss 14, Pp 15117-15127 (2023)
Abstract Background Dacomitinib significantly improves progression‐free survival and overall survival (OS) compared with gefitinib in patients with non–small‐cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR)‐activatin
Externí odkaz:
https://doaj.org/article/1050efaa4a7d45aa8b6299972f01d4bc
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract In the reverse transition in pipe flow, turbulent flow changes to less disturbed laminar flow. The entropy of the flow appears to decrease. This study examined the reverse transition experimentally and theoretically using entropy change and
Externí odkaz:
https://doaj.org/article/bbb8482455d944d88e6ea9e77564008f
Autor:
Yuki Katayama, MD, PhD, Tadaaki Yamada, MD, PhD, Kenji Morimoto, MD, PhD, Hiroyuki Fujii, MD, Satomi Morita, MD, PhD, Keiko Tanimura, MD, PhD, Takayuki Takeda, MD, PhD, Asuka Okada, MD, PhD, Shinsuke Shiotsu, MD, PhD, Yusuke Chihara, MD, PhD, Osamu Hiranuma, MD, Takahiro Yamada, MD, PhD, Takahiro Ota, MD, PhD, Taishi Harada, MD, Isao Hasegawa, MD, PhD, Masahiro Iwasaku, MD, PhD, Shinsaku Tokuda, MD, PhD, Noriyuki Tanaka, MD, PhD, Aya Miyagawa-Hayashino, MD, PhD, Koichi Takayama, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 3, Pp 100644- (2024)
Introduction: Multiple programmed death-ligand 1 (PD-L1) immunohistochemistry assays performed using different antibodies including DAKO 22C3, DAKO 28-8, and Ventana SP142 PD-L1—predictive markers for response to various immune checkpoint inhibitor
Externí odkaz:
https://doaj.org/article/3964141379334812bbe15faf7291e902
Autor:
Yoshiro Urade, Kay Yakushiji, Manabu Tsujimoto, Takahiro Yamada, Kazumasa Makise, Wataru Mizubayashi, Kunihiro Inomata
Publikováno v:
APL Materials, Vol 12, Iss 2, Pp 021132-021132-7 (2024)
Tantalum thin films sputtered on unheated silicon substrates are characterized with microwaves at around 10 GHz in a 10 mK environment. We show that the phase of tantalum with a body-centered cubic lattice (α-Ta) can be grown selectively by depositi
Externí odkaz:
https://doaj.org/article/def4c4d59ee44e679060bc49e06024b2
Autor:
Akihiro Yoshimura, Takayuki Takeda, Nobutaka Kataoka, Keiko Tanimura, Mototaka Fukui, Yusuke Chihara, Shota Takei, Hayato Kawachi, Kentaro Nakanishi, Yuta Yamanaka, Nobuyo Tamiya, Ryoichi Honda, Naoko Okura, Takahiro Yamada, Kiyoaki Uryu, Junji Murai, Shinsuke Shiotsu, Hiroshige Yoshioka, Tadaaki Yamada, Takayasu Kurata, Koichi Takayama
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionThe efficacy of second-line immune checkpoint inhibitor (ICI) therapy is limited in non-small cell lung cancer (NSCLC) patients with ≤ 49% PD-L1 expression. Although chemoimmunotherapy is a promising strategy, platinum-based chemotherap
Externí odkaz:
https://doaj.org/article/8d57729f3fdc4dbb893f9ca297d30e84