Zobrazeno 1 - 10
of 493
pro vyhledávání: '"TAKAHIRO NAKAYAMA"'
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-7 (2023)
Abstract The biliary epithelial cells (cholangiocytes) in the liver originate from undifferentiated liver parenchymal cells (hepatoblasts) that are located adjacent to the portal vein. This differentiation process is driven by Notch signaling, which
Externí odkaz:
https://doaj.org/article/9c8896ea8dfb49fc861a4292036d8e1f
Autor:
Takahiro Nakayama, Akash K. Singh, Toshiyuki Fukutomi, Noriyuki Uchida, Yasuo Terao, Hiroki Hamada, Takahiro Muraoka, Eswaramoorthy Muthusamy, Tapas K. Kundu, Kimio Akagawa
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114101- (2024)
Summary: Syntaxin-1A (stx1a) repression causes a neurodevelopmental disorder phenotype, low latent inhibition (LI) behavior, by disrupting 5-hydroxytryptaminergic (5-HTergic) systems. Herein, we discovered that lysine acetyltransferase (KAT) 3B incre
Externí odkaz:
https://doaj.org/article/7082df1e29b6458ba0cf338791935a20
Autor:
Misato Masuyama, Norikazu Masuda, Hidetoshi Kawaguchi, Yutaka Yamamoto, Shigehira Saji, Takahiro Nakayama, Kenjiro Aogi, Keisei Anan, Shoichiro Ohtani, Nobuaki Sato, Toshimi Takano, Eriko Tokunaga, Seigo Nakamura, Yoshie Hasegawa, Masaya Hattori, Tomomi Fujisawa, Satoshi Morita, Miki Yamaguchi, Toshinari Yamashita, Daisuke Yotsumoto, Masakazu Toi, Shinji Ohno
Publikováno v:
Cancer Medicine, Vol 12, Iss 17, Pp 17718-17730 (2023)
Abstract Background The role of endocrine therapy in the treatment of patients in a postmenopausal hormonal state and with estrogen receptor (ER)‐positive, human epidermal growth factor receptor 2 (HER2)‐positive advanced or metastatic breast can
Externí odkaz:
https://doaj.org/article/caeec8fc425642ad8dfd47e91b38c921
Autor:
Naoto Sambe, Masaharu Yoshihara, Teppei Nishino, Ryosuke Sugiura, Takahiro Nakayama, Chandra Louis, Satoru Takahashi
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract Objective A mammalian Delta-Notch signaling component, Notch1, has been suggested for its expression during the normal sperm development although its conditional deletion caused no apparent abnormalities. Since we established our original tr
Externí odkaz:
https://doaj.org/article/770f38d900274e69a599aaf7efe5b9b5
Autor:
Mizuki Kato, Kayo Nakata, Toshitaka Morishima, Yoshihiro Kuwabara, Fumie Fujisawa, Nobuyoshi Kittaka, Takahiro Nakayama, Isao Miyashiro
Publikováno v:
Cancer Medicine, Vol 12, Iss 12, Pp 13774-13783 (2023)
Abstract Background In recent years, the survival of patients with breast cancer has improved. However, few published studies have a longer than 10‐year follow‐up. Conditional relative survival (CRS), which is relative survival (RS) of patients w
Externí odkaz:
https://doaj.org/article/ce81ac7c059040d8b6ece72fbffdc944
Autor:
Ryosuke Sugiura, Takahiro Nakayama, Teppei Nishino, Naoto Sambe, Freddy Radtke, Masaharu Yoshihara, Satoru Takahashi
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Objective A Delta-Notch signaling component, Notch1, is involved in the normal development and multiple disorders of the kidney. Although the increase in Notch1 signaling is crucial to these pathogeneses, the basal signaling level in ‘heal
Externí odkaz:
https://doaj.org/article/7c1bf0cc20784688bc9b986e9d750616
Autor:
Satoshi Suzuki, Maki Kusumi, Tomoko Maeda, Kiyotaka Kawai, Toshihiro Kawamura, Eri Okamoto, Toushun Jo, Ryo Tsutsumi, Satoru Takamizawa, Takahiro Nakayama, Motowo Nabeta, Yukio Nishiyama, Mari Nomiyama, Kenji Furui, Yoshiharu Morimoto, Osamu Tsutsumi
Publikováno v:
Fertility & Reproduction, Vol 05, Iss 01, Pp 21-28 (2023)
Objective: To determine whether endometrial thickening is an important factor for pregnancy outcomes in platelet-rich plasma (PRP) treatment for patients with thin endometrium. Methods: Data from the registry database of the Japan Gynecologic PRP Stu
Externí odkaz:
https://doaj.org/article/4875a5fbe84c4bcebbdde244ff041553
Autor:
Masataka Sawaki, Naruto Taira, Yukari Uemura, Tsuyoshi Saito, Shinichi Baba, Kokoro Kobayashi, Hiroaki Kawashima, Michiko Tsuneizumi, Noriko Sagawa, Hiroko Bando, Masato Takahashi, Miki Yamaguchi, Tsutomu Takashima, Takahiro Nakayama, Masahiro Kashiwaba, Toshiro Mizuno, Yutaka Yamamoto, Hiroji Iwata, Tatsuya Toyama, Koichiro Tsugawa, Takuya Kawahara, Hirofumi Mukai
Publikováno v:
Breast, Vol 66, Iss , Pp 245-254 (2022)
Purpose: To gauge the effects of treatment practices on prognosis for older patients with HER2-positive early breast cancer, particularly to determine whether adjuvant trastuzumab alone can offer benefit over no adjuvant therapy. This is a prospectiv
Externí odkaz:
https://doaj.org/article/a945b7265854493eb752770a4643139b
Autor:
Masahiro Sonoo, Takamichi Kanbayashi, Shunsuke Kobayashi, Hiromasa Matsuno, Takahiro Nakayama, Ichiro Imafuku, Tetsuo Ando, Toshio Fukutake
Publikováno v:
Brain and Behavior, Vol 13, Iss 8, Pp n/a-n/a (2023)
Abstract Background and purpose The diagnosis of functional neurological disorder should be actively made based on the neurological signs. We described two new complementary signs to diagnose functional weakness of the lower limb, “weak gluteus max
Externí odkaz:
https://doaj.org/article/1a42601258d946f89617a9b74638d027
Autor:
Yukiko Seto, Nobuyoshi Kittaka, Azusa Taniguchi, Haruka Kanaoka, Satomi Nakajima, Yuri Oyama, Hiroki Kusama, Noriyuki Watanabe, Saki Matsui, Minako Nishio, Fumie Fujisawa, Koji Takano, Hideyuki Arita, Takahiro Nakayama
Publikováno v:
Surgical Case Reports, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Background Pegfilgrastim (PEG) is a sustained-duration pegylated form of filgrastim, a granulocyte-colony stimulating factor agent that is widely used as prophylaxis against febrile neutropenia during chemotherapy. We report the case of a br
Externí odkaz:
https://doaj.org/article/c06cbb992957436aa8b3dd3d5e8dedb8