Zobrazeno 1 - 10
of 262
pro vyhledávání: '"TAKAFUMI NAKAMURA"'
Autor:
Midori Yamashita, Mamoru Tasaki, Ryuji Murakami, Yukinori Arai, Takafumi Nakamura, Shinsuke Nakao
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 422-432 (2021)
Characterization of the intratumoral immune status is important for developing immunotherapies and evaluating their antitumor effectiveness. CD8+ T cells are one of the most important cell types that directly and indirectly contribute to antitumor ef
Externí odkaz:
https://doaj.org/article/68c97007a1944f55bdad940f1f063c9f
Autor:
Satoru Takahashi, Shigeki Aoki, Atsushi Iyono, Ayaka Karasuno, Kohichi Kodama, Ryosuke Komatani, Masahiro Komatsu, Masahiro Komiyama, Kenji Kuretsubo, Toshitsugu Marushima, Syota Matsuda, Kunihiro Morishima, Misaki Morishita, Naotaka Naganawa, Mitsuhiro Nakamura, Motoya Nakamura, Takafumi Nakamura, Yuya Nakamura, Noboru Nakano, Toshiyuki Nakano, Kazuma Nakazawa, Akira Nishio, Miyuki Oda, Hiroki Rokujo, Osamu Sato, Kou Sugimura, Atsumu Suzuki, Mayu Torii, Saya Yamamoto, Masahiro Yoshimoto
Publikováno v:
The Astrophysical Journal, Vol 960, Iss 1, p 47 (2023)
We are developing the Gamma-Ray Astro-Imager with Nuclear Emulsion project, designed for 10 MeV–100 GeV cosmic γ -ray observations with a high angular resolution (5′/0.°08 at 1–2 GeV) and a polarization-sensitive large-aperture (∼10 m ^2 )
Externí odkaz:
https://doaj.org/article/8c672c050b1846a59b9e4cdc3e19057d
Autor:
Motomu Nakatake, Hajime Kurosaki, Nozomi Kuwano, Kosuke Horita, Mai Ito, Hiromichi Kono, Tomotaka Okamura, Kosei Hasegawa, Yasuhiro Yasutomi, Takafumi Nakamura
Publikováno v:
Molecular Therapy: Oncolytics, Vol 14, Iss , Pp 159-171 (2019)
Vaccinia virus (VV) has been utilized in oncolytic virotherapy, but it risks a host antiviral immune response. VV has an extracellular enveloped virus (EEV) form consisting of a normal virion covered with a host-derived outer membrane that enables it
Externí odkaz:
https://doaj.org/article/62edb807eaa94f1ca4186d396229d2e9
Autor:
Kosuke Horita, Hajime Kurosaki, Motomu Nakatake, Nozomi Kuwano, Tetsuro Oishi, Hiroaki Itamochi, Sho Sato, Hiromichi Kono, Mai Ito, Kosei Hasegawa, Tasuku Harada, Takafumi Nakamura
Publikováno v:
Molecular Therapy: Oncolytics, Vol 13, Iss , Pp 35-48 (2019)
Oncolytic vaccinia virus (OVV) has demonstrated appropriate safety profiles for clinical development. Although designed to kill cancer cells efficiently, OVV sensitivity varies in individual cancers, and predictive biomarkers of therapeutic responses
Externí odkaz:
https://doaj.org/article/54a365e194da4d77a77a032f2fc828f0
Autor:
Mika Sugihara, Takahito Miyake, Yasunari Miyagi, Takashi Oda, Yukiko Hazama, Rikiya Sano, Takafumi Nakamura, Mitsuru Shiota, Koichiro Shimoya
Publikováno v:
Reproductive Medicine and Biology, Vol 17, Iss 4, Pp 474-480 (2018)
Abstract Purpose Recently, endoscopic surgeries are widely performed in the gynecological field. Several studies on the use of local anesthesia for pain control after laparoscopic surgery have been conducted; however, its effects remain controversial
Externí odkaz:
https://doaj.org/article/fbf87c84bb604db6afdaca53f7d1316d
Publikováno v:
Molecular Therapy: Oncolytics, Vol 6, Iss C, Pp 57-68 (2017)
Multiple myeloma is a malignancy of plasma cells of the bone marrow. Although the prognosis is variable, no curative therapy has been defined. Vaccinia virus infects cancer cells and kills such cells in a variety of ways. These include direct infecti
Externí odkaz:
https://doaj.org/article/94309629583d4cd79ebe2feb386b3e89
Autor:
Hajime Kurosaki, Motomu Nakatake, Teruhisa Sakamoto, Nozomi Kuwano, Masato Yamane, Kenta Ishii, Yoshiyuki Fujiwara, Takafumi Nakamura
Publikováno v:
Cells, Vol 10, Iss 5, p 985 (2021)
Engineered vaccinia virus serves as an oncolytic virus for cancer virotherapy. We evaluated the oncolytic characteristics of VGF- and O1-deleted recombinant mitogen-activated protein kinase (MAPK)-dependent vaccinia virus (MDRVV). We found that compa
Externí odkaz:
https://doaj.org/article/0e08d69ca9df49cbbcb9714923818687
Autor:
Mihyon Song, MD, Hiroshi Ishii, MS, Masahiro Toda, PhD, Takuji Tomimatsu, PhD, Hironobu Katsuyama, PhD, Takafumi Nakamura, PhD, Yuichiro Nakai, PhD, Koichiro Shimoya, PhD
Publikováno v:
Sexual Medicine, Vol 2, Iss 4, Pp 153-158 (2014)
Introduction: Female sexual function changes considerably during pregnancy and the postpartum period. In addition, women's physical and mental health, endocrine secretion, and internal and external genitalia vary during these times. However, there ar
Externí odkaz:
https://doaj.org/article/a521ac1dc5b1448e86c881758f2f96fd
Autor:
Takayuki Nakamura, Tatsuya Okada, Motoyoshi Endo, Tsuyoshi Kadomatsu, Takuya Taniwaki, Akira Sei, Haruki Odagiri, Tetsuro Masuda, Toru Fujimoto, Takafumi Nakamura, Yuichi Oike, Hiroshi Mizuta
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85542 (2014)
Chronic inflammation and subsequent fibrosis induced by mechanical stress play an important role in ligamentum flavum (LF) hypertrophy and degeneration in patients with lumbar spinal canal stenosis (LSCS). Angiopoietin-like protein 2 (Angptl2) is a c
Externí odkaz:
https://doaj.org/article/460eb03b680847acbe38a2835c3a7f65
Autor:
Kah-Whye Peng, Lynn C. Hartmann, Silvana Canevari, Mariangela Figini, Ann Oberg, Yasuhiro Ikeda, Mary Harvey, Takafumi Nakamura, Kosei Hasegawa
Purpose: Attenuated measles viruses are promising experimental anticancer agents currently being evaluated in a phase I dose escalation trial for ovarian cancer patients. Virus attachment, entry, and subsequent intercellular fusion between infected a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a6c8eb6d809ddc745e52cc8dac8f20
https://doi.org/10.1158/1078-0432.c.6518214
https://doi.org/10.1158/1078-0432.c.6518214
