Zobrazeno 1 - 10
of 87
pro vyhledávání: '"TAISUKE IMAMURA"'
Autor:
Taisuke Imamura, Shuhei Komatsu, Keiji Nishibeppu, Jun Kiuchi, Takuma Ohashi, Hirotaka Konishi, Atsushi Shiozaki, Yusuke Yamamoto, Ryo Moriumura, Hisashi Ikoma, Toshiya Ochiai, Eigo Otsuji
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background This study aims to explore novel microRNAs in urine for screening and predicting clinical characteristics in pancreatic cancer (PC) patients using a microRNA array-based approach. Methods We used the Toray® 3D-Gene microRNA array
Externí odkaz:
https://doaj.org/article/19b37fc3f20042018afdbbd9a9dfa686
Autor:
Masanori Nakamura, Yukiyasu Okamura, Keiichi Ohshima, Teiichi Sugiura, Ryo Ashida, Katsuhisa Ohgi, Etsuro Bando, Keiichi Fujiya, Akio Shiomi, Hiroyasu Kagawa, Taisuke Imamura, Goro Nakayama, Yasuhiro Kodera, Katsuhiko Uesaka, Nobuyuki Ohike, Tomoko Norose, Keiko Sasaki, Takashi Sugino, Sumiko Ohnami, Takeshi Nagashima, Kenichi Urakami, Yasuto Akiyama, Ken Yamaguchi
Publikováno v:
Cancer Medicine, Vol 12, Iss 10, Pp 11491-11502 (2023)
Abstract Background Small intestine carcinoma (SIC) cases in Japan have recently been treated with chemotherapy according to colorectal carcinoma classification, while papilla of Vater carcinoma (PVC) cases according to cholangiocarcinoma (CHC) class
Externí odkaz:
https://doaj.org/article/90fe44a7d8d54390a3170b7b4a8224c9
Autor:
Taisuke Imamura, Ryo Ashida, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Yukiyasu Okamura, Katsuhisa Ohgi, Sumiko Ohnami, Takeshi Nagashima, Ken Yamaguchi
Publikováno v:
Annals of Gastroenterological Surgery, Vol 7, Iss 3, Pp 491-502 (2023)
Abstract Background Pancreatic cancer (PC) is one of the most aggressive cancers worldwide. Although many studies have investigated genomic alterations, the genomic landscape of Japanese PC patients has not been fully elucidated. Methods We used whol
Externí odkaz:
https://doaj.org/article/aee6e68457b443c18d26b791aa107919
Autor:
Taisuke Imamura, Ryo Ashida, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Katsuhisa Ohgi, Mihoko Yamada, Shimpei Otsuka, Keiichi Hatakeyama, Takeshi Nagashima, Takashi Sugino, Kenichi Urakami, Yasuto Akiyama, Ken Yamaguchi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract In pancreatic cancer (PC), Tumor mutation burden (TMB) has been reported to be lower than in other cancers, with its clinical significance remaining unclear. We analyzed the dataset of whole-exome sequencing and gene expression profiling of
Externí odkaz:
https://doaj.org/article/185d8dbe29404cfab80d48a8d53a6de5
Autor:
Taisuke Imamura, Yukiyasu Okamura, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Shimpei Otsuka, Sumiko Ohnami, Takeshi Nagashima, Keiichi Hatakeyama, Takashi Sugino, Kenichi Urakami, Yasuto Akiyama, Ken Yamaguchi
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Multiple mutation (MM) within a single gene has recently been reported as a mechanism involved in carcinogenesis. The present study investigated the clinical significance of MMs in hepatocellular carcinoma (HCC). Methods Two hundr
Externí odkaz:
https://doaj.org/article/a9e551d267724b08a56b352494c5a412
Autor:
Taisuke Imamura, Yukiyasu Okamura, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Shimpei Otsuka, Sumiko Ohnami, Takeshi Nagashima, Keiichi Hatakeyama, Yuko Kakuda, Takashi Sugino, Kenichi Urakami, Yasuto Akiyama, Ken Yamaguchi
Publikováno v:
Cancer Medicine, Vol 11, Iss 8, Pp 1769-1786 (2022)
Abstract Introduction The genomic characteristics of hepatocellular carcinoma (HCC) after a sustained virological response (SVR) and its differences according to whether an SVR was achieved by treatment with direct‐acting antivirals (DAA) or interf
Externí odkaz:
https://doaj.org/article/cda7410014fc4f75b329364b7e281b20
Autor:
Jun Kiuchi, Shuhei Komatsu, Taisuke Imamura, Keiji Nishibeppu, Katsutoshi Shoda, Tomohiro Arita, Toshiyuki Kosuga, Hirotaka Konishi, Atsushi Shiozaki, Kazuma Okamoto, Hitoshi Fujiwara, Daisuke Ichikawa, Eigo Otsuji
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-8 (2019)
Abstract Recent studies identified that low levels of tumour suppressor microRNAs (miRNAs) in plasma/serum relate to tumour progression and poor outcomes in cancers. We selected six candidates (miR-126, 133b, 143, 203, 338-3p, 655) of tumour suppress
Externí odkaz:
https://doaj.org/article/4c787cc4f9da49289ee69f94ab01a1fa
Autor:
Keiji Nishibeppu, Shuhei Komatsu, Daisuke Ichikawa, Taisuke Imamura, Toshiyuki Kosuga, Kazuma Okamoto, Hirotaka Konishi, Atsushi Shiozaki, Hitoshi Fujiwara, Eigo Otsuji
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-6 (2018)
Abstract Background Although adjuvant chemotherapy with S-1 after curative gastrectomy has been performed as a standard treatment for Stage II and III gastric cancer (GC) in Japan, patients with Stage III GC still have a high incidence of recurrence
Externí odkaz:
https://doaj.org/article/0f5cce47a37c4511a5073b6b579ffb37
Autor:
Taisuke Imamura, Shuhei Komatsu, Daisuke Ichikawa, Mahito Miyamae, Wataru Okajima, Takuma Ohashi, Jun Kiuchi, Keiji Nishibeppu, Hirotaka Konishi, Atsushi Shiozaki, Ryo Morimura, Hisashi Ikoma, Toshiya Ochiai, Kazuma Okamoto, Hiroki Taniguchi, Eigo Otsuji
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract This study explored decreased tumor suppressor microRNA (miRNA) plasma levels in pancreatic cancer (PCa) patients to clarify their potential as novel biomarkers and therapeutic targets. We used the microRNA array-based approach to select can
Externí odkaz:
https://doaj.org/article/9110cec5bf674e4f95c5b2b2a7305803
Autor:
Tsutomu Kawaguchi, Shuhei Komatsu, Daisuke Ichikawa, Masahiro Tsujiura, Hiroki Takeshita, Shoji Hirajima, Mahito Miyamae, Wataru Okajima, Takuma Ohashi, Taisuke Imamura, Jun Kiuchi, Hirotaka Konishi, Atsushi Shiozaki, Kazuma Okamoto, Eigo Otsuji
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 9, p 1459 (2016)
MicroRNAs (miRNAs) are short noncoding RNAs that post-transcriptionally regulate gene expression and play important roles in various physiological and developmental processes such as oncogenic or tumor suppressive regulators. Specific miRNA expressio
Externí odkaz:
https://doaj.org/article/f3d2ce9f63b9452585e304cde178ce31