Activation of TAF9 via Danshensu-Induced Upregulation of HDAC1 Expression Alleviates Non-alcoholic Fatty Liver Disease

Autor: Ruiwen Wang, Zhecheng Wang, Ruimin Sun, Rong Fu, Yu Sun, Meiyang Zhu, Yunfei Geng, Dongyan Gao, Xiaofeng Tian, Yan Zhao, Jihong Yao

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Fatty acid β-oxidation is an essential pathogenic mechanism in nonalcoholic fatty liver disease (NAFLD), and TATA-box binding protein associated factor 9 (TAF9) has been reported to be involved in the regulation of fatty acid β-oxidation. However,

Externí odkaz: https://doaj.org/article/5e91aa1943114e12a54876c54199f945

Activation of TAF9 via Danshensu-Induced Upregulation of HDAC1 Expression Alleviates Non-alcoholic Fatty Liver Disease

Autor: Xiaofeng Tian, Dongyan Gao, Ruimin Sun, Jihong Yao, Yu Sun, Yan Zhao, Ruiwen Wang, Rong Fu, Yunfei Geng, Zhecheng Wang, Meiyang Zhu

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Fatty acid β-oxidation is an essential pathogenic mechanism in nonalcoholic fatty liver disease (NAFLD), and TATA-box binding protein associated factor 9 (TAF9) has been reported to be involved in the regulation of fatty acid β-oxidation. However,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074c0381bc545e0c8d5444a07485b291
https://www.frontiersin.org/articles/10.3389/fphar.2021.775528/full

Granulocyte Colony-Stimulating Factor-Induced TAF9 Modulates P53-TRIAP1-CASP3 Axis to Prevent Retinal Ganglion Cell Death after Optic Nerve Ischemia

Autor: Chin-Te Huang, Yao-Tseng Wen, Rong Kung Tsai, Keh-Liang Lin

BackgroundOptic nerve head (ONH) infarct can result in progressive retinal ganglion cell (RGC) death. Some evidences indicated that the granulocyte colony-stimulating factor (GCSF) provides positive effects against ischemic damage on RGCs. However, p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcd11c718ade75e25d5804a1a69e82c9
https://doi.org/10.21203/rs.3.rs-138908/v1

Chaperonin CCT Checkpoint Function in Basal Transcription Factor TFIID Assembly

Autor: Antonova, Simona V, Haffke, Matthias, Corradini, Eleonora, Mikuciunas, Mykolas, Low, Teck Y, Signor, Luca, van Es, Robert M, Gupta, Kapil, Scheer, Elisabeth, Vos, Harmjan R, Tora, László, Heck, Albert J R, Timmers, H T Marc, Berger, Imre, Sub Biomol.Mass Spectrometry & Proteom., Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics

Publikováno v: Antonova, S V, Haffke, M, Corradini, E, Mikuciunas, M, Low, T Y, Signor, L, Van-Es, R M, Gupta, K, Scheer, E, Vos, H R, Tora, L, Heck, A J R, Timmers, H T M & Berger, I 2018, ' Chaperonin CCT Checkpoint Function in Basal Transcription Factor TFIID Assembly ', Nature Structural and Molecular Biology, vol. 25, no. 12, pp. 1119-1127 . https://doi.org/10.1038/s41594-018-0156-z
Nature structural & molecular biology
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Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2018, 25 (12), pp.1119-1127
Nature Structural and Molecular Biology, 25, 1119. Nature Publishing Group
Nature Structural and Molecular Biology, 2018, 25 (12), pp.1119-1127

TFIID is a cornerstone of eukaryotic gene regulation. Distinct TFIID complexes with unique subunit compositions exist and several TFIID subunits are shared with other complexes, thereby conveying precise cellular control of subunit allocation and fun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512313183efc01df34196b46bc27680a
https://hdl.handle.net/1983/7cb0b29b-a4ee-473f-b61c-56492e05ee3f

The chromatin scaffold protein SAFB1 localizes SUMO-1 to the promoters of ribosomal protein genes to facilitate transcription initiation and splicing

Autor: Michael A. Freitas, Xiaoyan Guan, Hui Wen Liu, Tapahsama Banerjee, Jeffrey D. Parvin

Publikováno v: Nucleic Acids Research

Early steps of gene expression are a composite of promoter recognition, promoter activation, RNA synthesis and RNA processing, and it is known that SUMOylation, a post-translational modification, is involved in transcription regulation. We previously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f35ca367edc80a04a938a5bdb55f538
http://europepmc.org/articles/PMC4402547