Zobrazeno 1 - 6
of 6
pro vyhledávání: '"TADAKIYO NAKAGAWA"'
Autor:
Sen Takeshita, Mizuki Dohi, Wataru Miyanaga, Kazuhiro Nakano, Tadakiyo Nakagawa, Yoriko Okamatsu, Noriko Kawasaki
Publikováno v:
International Journal of Molecular Medicine
Impaired glycogen synthesis and turnover are common in insulin resistance and type 2 diabetes. As glycogen synthase (GS) is a key enzyme involved in the synthetic process, it presents a promising therapeutic target for the treatment of type 2 diabete
Autor:
Hideto Fukui, Tadashi Nakata, Tadakiyo Nakagawa, Hiroyuki Koshino, Yoshinori Tsuchiya, Keiko Fujita
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:2081-2086
Artificial analogs of mycalamide A, a potent antitumor and antiviral compound isolated from a New Zealand marine sponge, were synthesized and their biological activities were tested.
Autor:
KAZUHIRO NAKANO, SEN TAKESHITA, NORIKO KAWASAKI, WATARU MIYANAGA, YORIKO OKAMATSU, MIZUKI DOHI, TADAKIYO NAKAGAWA
Publikováno v:
International Journal of Molecular Medicine; 2017, Vol. 39 Issue 4, p841-850, 10p
Autor:
Yoichiro Shima, Seinosuke Iwata, Shingo Makino, Masataka Shoji, Noriyasu Kataoka, Mitsuo Takahashi, Tadakiyo Nakagawa, Hiroshi Yamamoto, Suzuki Nobuyasu, Seiji Oono, Shunji Takehana, Kazumi Tashiro, Takashi Kayahara, Takashi Tsuji, Ryota Yoshimoto, Kazuyuki Sagi, Masahiro Yamanashi, Kohki Ishikawa, Yumiko Fukuda, Masaru Takayanagi, Kaoru Takenaka, Sayaka Shima, Kuniya Sakurai
Publikováno v:
Journal of medicinal chemistry. 46(10)
An inhibitor of factor Xa (fXa), the m-substituted benzamidine AXC1578 (1a), was structurally modified with the aim of increasing its potency. In particular, pyruvic acid and propionic acid substituents were incorporated into the P1 benzamidine moiet
Autor:
Seinosuke Iwata, Akira Takahara, Yumiko Fukuda, Masataka Shoji, Masaru Takayanagi, Takashi Kayahara, Shunji Takehana, Masahiro Yamanashi, Tadakiyo Nakagawa, Kazuyuki Sagi
Publikováno v:
Japanese Journal of Pharmacology. 82:213
Publikováno v:
HETEROCYCLES. 42:159