Intracisternal administration of tanshinone IIA-loaded nanoparticles leads to reduced tissue injury and functional deficits in a porcine model of ischemic stroke.

Autor: Waters ES; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, United States.; Biomedical and Health Sciences Institute, University of Georgia, Athens, GA 30602, United States.; Department of Animal and Dairy Science, College of Agricultural and Environmental Sciences, University of Georgia, Athens, GA 30602, United States., Kaiser EE; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, United States.; Biomedical and Health Sciences Institute, University of Georgia, Athens, GA 30602, United States., Yang X; Department of Chemistry, Franklin College of Arts and Sciences, University of Georgia, Athens, GA 30602, United States., Fagan MM; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, United States.; Department of Animal and Dairy Science, College of Agricultural and Environmental Sciences, University of Georgia, Athens, GA 30602, United States., Scheulin KM; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, United States.; Biomedical and Health Sciences Institute, University of Georgia, Athens, GA 30602, United States.; Department of Animal and Dairy Science, College of Agricultural and Environmental Sciences, University of Georgia, Athens, GA 30602, United States., Jeon JH; Department of Foods and Nutrition, College of Family and Consumer Sciences, University of Georgia, Athens, GA 30602, United States., Shin SK; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, United States.; Department of Animal and Dairy Science, College of Agricultural and Environmental Sciences, University of Georgia, Athens, GA 30602, United States.; Interdisciplinary Toxicology Program, College of Pharmacy, University of Georgia, Athens, GA 30602, United States., Kinder HA; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, United States.; Biomedical and Health Sciences Institute, University of Georgia, Athens, GA 30602, United States.; Department of Animal and Dairy Science, College of Agricultural and Environmental Sciences, University of Georgia, Athens, GA 30602, United States., Kumar A; Department of Chemistry, Franklin College of Arts and Sciences, University of Georgia, Athens, GA 30602, United States., Platt SR; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, United States.; Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, United States., Duberstein KJ; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, United States.; Department of Animal and Dairy Science, College of Agricultural and Environmental Sciences, University of Georgia, Athens, GA 30602, United States., Park HJ; Department of Foods and Nutrition, College of Family and Consumer Sciences, University of Georgia, Athens, GA 30602, United States., Xie J; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, United States.; Department of Chemistry, Franklin College of Arts and Sciences, University of Georgia, Athens, GA 30602, United States., West FD; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, United States.; Biomedical and Health Sciences Institute, University of Georgia, Athens, GA 30602, United States.; Department of Animal and Dairy Science, College of Agricultural and Environmental Sciences, University of Georgia, Athens, GA 30602, United States.; Interdisciplinary Toxicology Program, College of Pharmacy, University of Georgia, Athens, GA 30602, United States.

Publikováno v: IBRO neuroscience reports [IBRO Neurosci Rep] 2021 Jan 05; Vol. 10, pp. 18-30. Date of Electronic Publication: 2021 Jan 05 (Print Publication: 2021).