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Focal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma

Autor: Bart Kok, Tonny Lagerweij, Jaco C. Knol, Giulia Mantini, Geert Kazemier, T.Y.S. Le Large, Sander R. Piersma, B. El Hassouni, Maarten F. Bijlsma, Elisa Giovannetti, Alexander A. Henneman, Connie R. Jimenez, H.W.M. van Laarhoven, Luca Morelli, Niccola Funel, R. R. de Haas, Thang V. Pham

Publikováno v: Journal of Experimental & Clinical Cancer Research : CR
le Large, T Y S, Bijlsma, M F, el Hassouni, B, Mantini, G, Lagerweij, T, Henneman, A A, Funel, N, Kok, B, Pham, T V, de Haas, R, Morelli, L, Knol, J C, Piersma, S R, Kazemier, G, van Laarhoven, H W M, Giovannetti, E & Jimenez, C R 2021, ' Focal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma ', JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, vol. 40, no. 1, 91 . https://doi.org/10.1186/s13046-021-01892-z
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 40(1):91. BioMed Central
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)
Journal of experimental & clinical cancer research, 40(1):91. BioMed Central

Background Pancreatic ductal adenocarcinoma (PDAC) is a very lethal disease, with minimal therapeutic options. Aberrant tyrosine kinase activity influences tumor growth and is regulated by phosphorylation. We investigated phosphorylated kinases as ta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8214a63d52784a518e8ca3893d4ce0e7
http://www.scopus.com/inward/record.url?scp=85102552220&partnerID=8YFLogxK

Co-expression analysis of pancreatic cancer proteome reveals biology and prognostic biomarkers

Autor: Geert Kazemier, Thang V. Pham, Elisa Giovannetti, Giulia Mantini, Connie R. Jimenez, A. M. Vallés, M. Capula, Niccola Funel, Sander R. Piersma, Maarten F. Bijlsma, T.Y.S. Le Large

Publikováno v: Cellular Oncology (Dordrecht)
Cellular oncology, 43(6), 1147-1159. IOS Press
Cellular Oncology, 43(6), 1147-1159. IOS Press
Mantini, G, Vallés, A M, Le Large, T Y S, Capula, M, Funel, N, Pham, T V, Piersma, S R, Kazemier, G, Bijlsma, M F, Giovannetti, E & Jimenez, C R 2020, ' Co-expression analysis of pancreatic cancer proteome reveals biology and prognostic biomarkers ', Cellular Oncology, vol. 43, no. 6, pp. 1147-1159 . https://doi.org/10.1007/s13402-020-00548-y

Purpose Despite extensive biological and clinical studies, including comprehensive genomic and transcriptomic profiling efforts, pancreatic ductal adenocarcinoma (PDAC) remains a devastating disease, with a poor survival and limited therapeutic optio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece94507a00f5b9d075e82d025de5367
https://pubmed.ncbi.nlm.nih.gov/32860207

Blood platelet RNA yields a new diagnostic prospective for accurate detection and staging of pancreatic ductal adenocarcinoma

Autor: M. Arkani, Thomas Wurdinger, Govert Dwarshuis, Lenka N.C. Boyd, Maarten F. Bijlsma, T.Y.S. Le Large, E Van Der Lelij, M. Capula, Elisa Giovannetti, Laura L. Meijer, Nik Sol, Adam E Frampton, Edward Post, Luca Morelli, Geert Kazemier, Giulia Mantini, M.G. Besselink, Myron G. Best, F. Daams, S. In ’T Veld, B.M. Zonderhuis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75faa76d2543ec202a54f7d2560f4d81
http://hdl.handle.net/11568/1066138

Co-expression analysis of proteomics data reveal tumor biology and prognostic biomarkers for pancreatic ductal adenocarcinoma

Autor: A. M. Vallés, Geert Kazemier, T.Y.S. Le Large, Elisa Giovannetti, Giulia Mantini, M. Capula, N. Funel, Sander R. Piersma, Maarten F. Bijlsma, Connie R. Jimenez, Thang V. Pham

Publikováno v: Pancreatology. 20:S133-S134

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b15e65a4b82e4ebf7bd6af185fc43ee5
https://doi.org/10.1016/j.pan.2020.07.248