Association of plasma lipids and apolipoproteins with the insulin response element in the apoC-III promoter region in familial combined hyperlipidemia

Autor: M. Groenendijk, R.M. Cantor, N.H.H.C. Blom, J.I. Rotter, T.W.A. de Bruin, G.M. Dallinga-Thie

Publikováno v: Journal of Lipid Research, Vol 40, Iss 6, Pp 1036-1044 (1999)

The apoAI-CIII-AIV gene cluster, located on chromosome 11, contributes to the phenotype of familial combined hyperlipidemia (FCH), but this contribution is genetically complex. Combinations of haplotypes, based on three restriction enzyme polymorphis

Externí odkaz: https://doaj.org/article/f6274cbe209c492994c8c80ad3499bc2

Direct association of a promoter polymorphism in the CD36/FAT fatty acid transporter gene with Type 2 diabetes mellitus and insulin resistance

Autor: T.W.A. de Bruin, Ellen E. Blaak, M. G. P. Magagnin, C.J.H. van der Kallen, Eva Corpeleijn, M. Kruijshoop, Wim H. M. Saris, Edith J. M. Feskens

Publikováno v: Diabetic Medicine, 23(8), 907-911. Wiley
Diabetic medicine 23 (2006) 8
Diabetic medicine, 23(8), 907-911

AIMS: The membrane-bound fatty acid transporter CD36/FAT may play a role in disturbed fatty acid handling as observed in the metabolic syndrome and Type 2 diabetes mellitus (T2DM). Genetic variation in the CD36 gene may contribute to the aetiology of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a3958750e068fb4b50570628b666cb
https://doi.org/10.1111/j.1464-5491.2006.01888.x

Common variants in the ATP-sensitive K+ channel genes KCNJ11 (Kir6.2) and ABCC8 (SUR1) in relation to glucose intolerance: population-based studies and meta-analyses1

Autor: M. M. Schaap, Edith J. M. Feskens, B. Hoebee, T.W.A. de Bruin, Jacob C. Seidell, R.M. van Dam

Publikováno v: Diabetic Medicine. 22:590-598

Aims To evaluate the relation between common variants in the ATP-sensitive K(+) channel genes and glucose intolerance. Methods We conducted a meta-analysis of reported association studies in Caucasian populations for common variants in the ABCC8 (exo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14be44b323c9afc7c2d224eb01ca6b1e
https://doi.org/10.1111/j.1464-5491.2005.01465.x

Study on Lifestyle Intervention and Impaired Glucose Tolerance Maastricht (SLIM): preliminary results after one year

Autor: Edith J. M. Feskens, Ellen E. Blaak, Marco Mensink, T.W.A. de Bruin, Wim H. M. Saris

Publikováno v: International Journal of Obesity 27 (2003) 3
International Journal of Obesity, 27(3), 377-384. Nature Publishing Group
International Journal of Obesity, 27(3), 377-384

Study on Lifestyle Intervention and Impaired Glucose Tolerance Maastricht (SLIM): preliminary results after one year.Mensink M, Feskens EJ, Saris WH, De Bruin TW, Blaak EE.Department of Human Biology, Maastricht University, Maastricht, The Netherland

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75964260602d564aec92ff2213b3c811
https://doi.org/10.1038/sj.ijo.0802249

Caco-2 cells secrete two independent classes of lipoproteins with distinct density: effect of the ratio of unsaturated to saturated fatty acid

Autor: D.W. Erkelens, M.M.J. van Greevenbroek, T.W.A. de Bruin

Publikováno v: Atherosclerosis, 149(1), 25-31. Elsevier Ireland Ltd

Polarized Caco-2 cells can synthesize two distinct density classes of lipoproteins, i.e. chylomicron/VLDL (d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7895919c439384b5ae4e0a62eb2bec1
https://doi.org/10.1016/s0021-9150(99)00289-0