Zobrazeno 1 - 10
of 32
pro vyhledávání: '"T.S.B. Zwanenburg"'
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 317:163-173
Cyclosporine is an important therapeutic agent for transplant recipients and for a growing number of autoimmune diseases. Experimental animal and human data has indicated that cyclosporine is unlikely to be genotoxic. In contrast, azathioprine, an ag
Autor:
A. Cordier, T.S.B. Zwanenburg
Publikováno v:
Mutation research. 320(3)
Continuous in vitro treatment of human peripheral blood lymphocytes with cyclosporin A for 20 h and 44 h in the absence of metabolic activation decreased the mitotic index in a concentration-dependent way (MI about 35% at 50 micrograms/ml). In the pr
Publikováno v:
Mutation research. 287(1)
Using primary Chinese hamster embryonic cells, 10 known or suspected aneugens supplied as a part of the EC 4th Environmental Research and Development Programme were evaluated by the technique described by Dulout and Natarajan (1987). The chemicals in
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 95:1-6
Experimental evidence is presented for the involvement of DNA double-strand breaks in the formation of radiation-induced chromosomal aberrations. When X-irradiated cells were post-treated with single-strand specific Neurospora crassa endonuclease (NE
Autor:
L.A. Cannizzaro, N.S.F. Ma, Beverly S. Emanuel, Heinz Winking, S. Adolph, F.F.B. Elder, Juan A. Rey, Paul M. Kraemer, Ann C. Chandley, M.F. Bartholdi, T.S.B. Zwanenburg, D.M. Kurnit, J.B. Searle, Walther Traut, U. Francke, A.M. Joseph, P. Martinez-Castro, Terence J. Robinson, J. Benítez, T.B. Hargreave, L.S. Cram, M.C. Ramos, P. Goetz, Sanchez Cascos, R.M. Speed, A.T. Natarajan, F.A. Ray, J.A. Chapman
Publikováno v:
Cytogenetic and Genome Research. 38:I-VI
Autor:
T.S.B. Zwanenburg
Publikováno v:
Mutation Research/Genetic Toxicology. 206:395-409
Methanol extracts from 4 pairs of airconditioner filters (one fire-exposed and one control) from various locations (A, B, C and D) at various distances from the site of the fire were examined for their capacity to induce structural chromosomal aberra
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 127:155-168
Experiments have been performed to investigate whether BrdUrd- and CldUrd-substituted DNA contains lesions causing a delay in cell-cycle progression and induction of chromosomal aberrations. The presence of lesions has been determined directly by alk
Autor:
T.S.B. Zwanenburg
Publikováno v:
Chemosphere. 19:1088-1093
Publikováno v:
Mutation Research Letters. 144:41-49
Chinese hamster cells, containing BrdUrd-substituted DNA, were irradiated in the presence of 3-aminobenzamide with short-wave UV, long-wave UV or X-rays and analyzed for induced SCEs or chromosomal aberrations. The data presented in this paper show t