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Akademický článek

Assessment of the Reproducibility of Alginate Encapsulation of Pancreatic Islets Using the MTT Colorimetric Assay

Publikováno v: Cell Transplantation, Vol 3 (1994)

Radioisotope diffusion experiments demonstrate that alginate/polyaminoacid encapsulation can prevent antibody and cytotoxic cell contact in vitro. The unpredictable outcome of xenotransplantation of encapsulated islets may reflect incomplete encapsul

Externí odkaz: https://doaj.org/article/607101567152457ebcba7df36f294e12

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Akademický článek

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The influence of collagenase solvent on the isolation of islets from 5 week old pigs: a comparison of TCM-199 and UW

Autor: K.A. Heald, D.E. Topham, T.R. Jay, R. Downing

Publikováno v: Journal of Molecular Medicine. 77:83-86

Islet transplantation is a potential treatment for diabetes, but the techniques for islet isolation are inefficient and the recovery rates for isolated islets are often low. As the solutions employed during the isolation process may affect islet yiel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8acdea189763356a335144a1ed073110
https://doi.org/10.1007/s001090050307

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Are organ preservation solutions useful for the storage of isolated human islets?

Autor: K.A. Heald, M.B Paget, R. Downing, T.R. Jay

Publikováno v: Transplantation Proceedings. 36:1130-1132

Clinical islet transplantation invariably requires more than one donor per recipient. Delay between transplants could be reduced if islets were stored and transported between centers. This study assessed viability and response to glucose of isolated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606871524c703530336f153bdba57dd0
https://doi.org/10.1016/j.transproceed.2004.04.063

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Expression of the GALalpha(1-3)GAL epitope on pig islets

Autor: K.A. Heald, N. Boucher, N. Carless, R. Downing, T.R. Jay

Publikováno v: Journal of molecular medicine (Berlin, Germany). 77(1)

Expression of Galalpha(1-3)Gal on endothelium has been implicated in the rejection of porcine xenografts. The aim of this study was to determine whether expression of Galalpha(1-3)Gal on pig islets varies between pigs aged 5, 12 and 24 weeks, and to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab1b6a1bb6eae0a2669ec7fe389ebb5
https://pubmed.ncbi.nlm.nih.gov/9930956

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