Výsledky vyhledávání - "T.N. de Boer"

SAT0508 Lack of a clear disease modifying activity of celecoxib in treatment of end-stage knee osteoarthritis: a randomized observer blinded clinical trial

Autor: T.N. de Boer, J.M. van Laar, A.A. Polak, S.C. Mastbergen, A. M. Huisman, K. Coeleveld, EM Van Helvoort, J. W. J. Bijlsma, Fjpg Lafeber

Publikováno v: Poster Presentations.

Background Several studies suggest that celecoxib has beneficial effects on degenerated cartilage (1, 2). Together with effects on synovial tissue and bone, celecoxib was postulated to have disease modifying osteoarthritic drug (DMOAD) activity. Obje

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84ede5f01e6b28cb01d2107169686a31
https://doi.org/10.1136/annrheumdis-2017-eular.1454

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The chondroprotective effect of selective COX-2 inhibition in osteoarthritis: ex vivo evaluation of human cartilage tissue after in vivo treatment

Autor: Jwj Bijlsma, Simon C. Mastbergen, Daniel B.F. Saris, A.A. Polak, T.N. de Boer, F.J.P.G. Lafeber, A.M. Huisman, A.G. Niehoff, A. C. van Rinsum

Publikováno v: Osteoarthritis and Cartilage. 17:482-488

Summary Objective Recent in vitro studies showed that celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, protects human osteoarthritic cartilage tissue from degeneration. The objective was to substantiate these beneficial effects in an in vivo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79030e2d23b89838475b7fc1ed8fda3e
https://doi.org/10.1016/j.joca.2008.09.002

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In end stage osteoarthritis, cartilage tissue pentosidine levels are inversely related to parameters of cartilage damage

Autor: A.M. Huisman, T.N. de Boer, A.A. Polak, Jeroen DeGroot, F.P.J.G. Lafeber, Petra Vos, S.C. Mastbergen

Publikováno v: Osteoarthritis and Cartilage, 3, 20, 233-240

Objectives: Age is the most prominent predisposition for development of osteoarthritis (OA). Age-related changes of articular cartilage are likely to play a role. Advanced glycation endproducts (AGEs) accumulate in cartilage matrix with increasing ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b081d18d664396d67e68637c207c86
http://resolver.tudelft.nl/uuid:26be65b0-c0e9-4da1-8743-517729cca143

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Serum adipokines in osteoarthritis; comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage

Autor: A.M. Huisman, F.P.J.G. Lafeber, W.E. van Spil, T.N. de Boer, Simon C. Mastbergen, A.A. Polak, Jwj Bijlsma

Publikováno v: Osteoarthritis and cartilage. 20(8)

SummaryObjectiveAdipose tissue is an endocrine tissue releasing adipokines suggested to be involved in the pathogenesis of osteoarthritis (OA). Nevertheless, their relative contribution and exact mechanisms are still ambiguous. The aim of this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a06ea9a43b7893c17d5e93c9a05832
https://pubmed.ncbi.nlm.nih.gov/22595228

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SAT0334 Radiographic joint damage as a predictor of short-term clinical outcome of total knee replacement surgery

Autor: W.H. Noort-vanderLaan, T.N. de Boer, P.M.J. Welsing, A.M. Huisman, F.P.J.G. Lafeber, A.A. Polak, Simon C. Mastbergen

Publikováno v: Annals of the Rheumatic Diseases. 71:585.1-585

Background Osteoarthritis (OA) is a slowly progressive degenerative joint disorder most frequently seen in the middle aged and older people. OA has a high prevalence causing pain and loss of function. There is still no cure for the disease. The curre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f22dbe2594db9ab141b962ff2c5ee9d3
https://doi.org/10.1136/annrheumdis-2012-eular.3280

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Radiographic features, better than clinical features, represent actual joint degeneration and inflammation: considerations for total knee replacement surgery

Autor: A.A. Polak, W.H. Noort-vanderLaan, Jwj Bijlsma, Simon C. Mastbergen, T.N. de Boer, A.M. Huisman, F.P.J.G. Lafeber

Publikováno v: Osteoarthritis and Cartilage. :S166

s / Osteoarthritis and Cartilage 20 (2012) S54–S296 S166 compare mean change in knee function tests and KOOS subscales between the two visits. Spearman correlations were computed to compare the magnitude of change between objective knee function te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7880f16490d833b900635c077e59a95c

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