Zobrazeno 1 - 10
of 71
pro vyhledávání: '"T.M. Willemsen"'
Autor:
Chris W.J. van der Weijden, Anouk van der Hoorn, Yanming Wang, Antoon T.M. Willemsen, Rudi A.J.O. Dierckx, Adriaan A. Lammertsma, Erik F.J. de Vries
Publikováno v:
NeuroImage, Vol 264, Iss , Pp 119772- (2022)
Multiple sclerosis (MS) is an inflammatory demyelinating disease. Current treatments are focussed on immune suppression to modulate pathogenic activity that causes myelin damage. New treatment strategies are needed to prevent demyelination and promot
Externí odkaz:
https://doaj.org/article/c4758c9c41a04095b7da86b388448c8b
Autor:
Sanne K. Meles, Jelmer G. Kok, Bauke M. De Jong, Remco J. Renken, Jeroen J. de Vries, Jacoba M. Spikman, Aaltje L. Ziengs, Antoon T.M. Willemsen, Harm J. van der Horn, Klaus L. Leenders, Hubertus P.H. Kremer
Publikováno v:
NeuroImage: Clinical, Vol 19, Iss , Pp 90-97 (2018)
Introduction: We aimed to uncover the pattern of network-level changes in neuronal function in Spinocerebellar ataxia type 3 (SCA3). Methods: 17 genetically-confirmed SCA3 patients and 16 controls underwent structural MRI and static resting-state [18
Externí odkaz:
https://doaj.org/article/cfa1543eb3cd48bdbeceddbc1335c461
Autor:
Sjoukje van der Hoek, Douwe J. Mulder, Antoon T.M. Willemsen, Ton Visser, Andre Heeres, Riemer H.J.A. Slart, Philip H. Elsinga, Hiddo J.L. Heerspink, Jasper Stevens
Publikováno v:
Clinical Pharmacology & Therapeutics, 112(6), 1264-1270. Nature Publishing Group
Clinical Pharmacology & Therapeutics, 112(6), 1264-1270
Clinical Pharmacology & Therapeutics, 112(6), 1264-1270
The angiotensin receptor blocker telmisartan slows progression of kidney disease in patients with type 2 diabetes (T2D), yet many patients remain at high risk for progressive kidney function loss. The underlying mechanisms for this response variation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d766045727d4e40117ce46993381b10
https://doi.org/10.1002/cpt.2744
https://doi.org/10.1002/cpt.2744
Autor:
David Vállez García, Janine Doorduin, Antoon T.M. Willemsen, Rudi A.J.O. Dierckx, Andreas Otte
Publikováno v:
EBioMedicine, Vol 10, Iss C, Pp 249-257 (2016)
There is increasing evidence of central hyperexcitability in chronic whiplash-associated disorders (cWAD). However, little is known about how an apparently simple cervical spine injury can induce changes in cerebral processes. The present study was d
Externí odkaz:
https://doaj.org/article/629a51baea4946569148718235eaf898
Autor:
Lara Garcia-Varela, Pascalle Mossel, Pablo Aguiar, Daniel A. Vazquez-Matias, Aren van Waarde, Antoon T.M. Willemsen, Anna L. Bartels, Nicola A. Colabufo, Rudi A.J.O. Dierckx, Philip H. Elsinga, Gert Luurtsema
Publikováno v:
Journal of Controlled Release, 347, 500-507. Elsevier Bedrijfsinformatie b.v.
The Blood-Brain Barrier P-glycoprotein (P-gp) function can be altered in several neurodegenerative diseases and due to the administration of different drugs which may cause alterations in drug concentrations and consequently lead to a reduced effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644db18fdaf121d0c3e3563cb34e1b8f
https://research.rug.nl/en/publications/fd0171d8-0428-4ea1-abe0-b109a1b64289
https://research.rug.nl/en/publications/fd0171d8-0428-4ea1-abe0-b109a1b64289
Autor:
Erik F. J. de Vries, Rudi Dierckx, Anna Schildt, Antoon T.M. Willemsen, Jurgen W. A. Sijbesma, Vesna Sossi, Rodrigo Moraga-Amaro, Bruno Lima-Giacobbo, Janine Doorduin
Publikováno v:
Molecular Imaging and Biology, 22(4), 931-939. SPRINGER
Purpose: [18F]Fluoroethoxybenzovesamicol ([18F]FEOBV) is a radioligand for the vesicular acetylcholine transporter (VAChT), a marker of the cholinergic system. We evaluated the quantification of [18F]FEOBV in rats in control conditions and after part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63913b3984ed26ed4c6c707b865982b4
https://doi.org/10.1007/s11307-019-01466-8
https://doi.org/10.1007/s11307-019-01466-8
Autor:
Paul J. H. van Snick, Ronald Borra, Jenny Schaar, Johan R. de Jong, Rudi Dierckx, Antoon T.M. Willemsen, Walter Noordzij, Ronald Boellaard, Joyce van Sluis
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 60(7), 1031-1036
van Sluis, J J, de Jong, J, Schaar, J, Noordzij, W, van Snick, P, Dierckx, R, Borra, R, Willemsen, A & Boellaard, R 2019, ' Performance characteristics of the digital Biograph Vision PET/CT system ', Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol. 60, no. 7, pp. 1031-1036 . https://doi.org/10.2967/jnumed.118.215418
Journal of Nuclear Medicine, 60(7), 1031-1036. SOC NUCLEAR MEDICINE INC
van Sluis, J J, de Jong, J, Schaar, J, Noordzij, W, van Snick, P, Dierckx, R, Borra, R, Willemsen, A & Boellaard, R 2019, ' Performance characteristics of the digital Biograph Vision PET/CT system ', Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol. 60, no. 7, pp. 1031-1036 . https://doi.org/10.2967/jnumed.118.215418
Journal of Nuclear Medicine, 60(7), 1031-1036. SOC NUCLEAR MEDICINE INC
This study evaluated the performance of the Biograph Vision digital PET/CT system according to the NEMA NU 2-2012 standard (published by the National Electrical Manufacturers Association [NEMA]) to allow for a reliable, reproducible, and intersystemc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab94a8915a8e04cd872c7c4a6cf35101
https://doi.org/10.2967/jnumed.118.215418
https://doi.org/10.2967/jnumed.118.215418
Autor:
Guilherme Domingues Kolinger, Fransje E. Reesink, Antoon T.M. Willemsen, Bauke M. de Jong, Peter Paul De Deyn, Ronald Boellaard, Rudi Dierckx, David Vállez García
Publikováno v:
PLoS ONE
Kolinger, G D, García, D V L, Willemsen, A T M, Reesink, F E, de Jong, B M, Dierckx, R A J O, de Deyn, P P & Boellaard, R 2021, ' Amyloid burden quantification depends on PET and MR image processing methodology ', PLoS ONE, vol. 16, no. 3 March 2021, e0248122 . https://doi.org/10.1371/journal.pone.0248122
PLoS ONE, 16(3):e0248122. PUBLIC LIBRARY SCIENCE
PLOS ONE
PLoS ONE, 16(3 March 2021):e0248122. Public Library of Science
PLoS ONE, Vol 16, Iss 3, p e0248122 (2021)
Kolinger, G D, García, D V L, Willemsen, A T M, Reesink, F E, de Jong, B M, Dierckx, R A J O, de Deyn, P P & Boellaard, R 2021, ' Amyloid burden quantification depends on PET and MR image processing methodology ', PLoS ONE, vol. 16, no. 3 March 2021, e0248122 . https://doi.org/10.1371/journal.pone.0248122
PLoS ONE, 16(3):e0248122. PUBLIC LIBRARY SCIENCE
PLOS ONE
PLoS ONE, 16(3 March 2021):e0248122. Public Library of Science
PLoS ONE, Vol 16, Iss 3, p e0248122 (2021)
Quantification of amyloid load with positron emission tomography can be useful to assess Alzheimer’s Disease in-vivo. However, quantification can be affected by the image processing methodology applied. This study’s goal was to address how amyloi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ee6b9e963be88aceb59eb0d805968b
https://repository.uantwerpen.be/docstore/d:irua:6040
https://repository.uantwerpen.be/docstore/d:irua:6040
Autor:
Casper F. M. Franssen, Antoon T.M. Willemsen, Peter Jan van Laar, Jan Willem J. Elting, David Vállez García, Ralf Westerhuis, Marcel J.H. Aries, Johanna Kuipers, Harmke A. Polinder-Bos, Wim P. Krijnen, Carlo A. J. M. Gaillard, Riemer H. J. A. Slart, Gert Luurtsema, Ron T. Gansevoort
Publikováno v:
Polinder-Bos, H A, Elting, J W J, Aries, M J H, Vállez García, D, Willemsen, A T M, van Laar, P J, Kuipers, J, Krijnen, W P, Slart, R H J A, Luurtsema, G, Westerhuis, R, Gansevoort, R T, Gaillard, C A J M & Franssen, C F M 2020, ' Changes in cerebral oxygenation and cerebral blood flow during hemodialysis – A simultaneous near-infrared spectroscopy and positron emission tomography study ', Journal of Cerebral Blood Flow and Metabolism, vol. 40, no. 2, pp. 328-340 . https://doi.org/10.1177/0271678X18818652
Journal of Cerebral Blood Flow and Metabolism, 40(2), 328-340. SAGE Publications Inc.
Journal of Cerebral Blood Flow and Metabolism, 40(2), 328. Nature Publishing Group
Journal of Cerebral Blood Flow and Metabolism, 40(2), 328-340. Nature Publishing Group
J Cereb Blood Flow Metab
Journal of Cerebral Blood Flow and Metabolism, 40(2), 328-340. SAGE Publications Inc.
Journal of Cerebral Blood Flow and Metabolism, 40(2), 328. Nature Publishing Group
Journal of Cerebral Blood Flow and Metabolism, 40(2), 328-340. Nature Publishing Group
J Cereb Blood Flow Metab
Near-infrared spectroscopy (NIRS) is used to monitor cerebral tissue oxygenation (rSO2) depending on cerebral blood flow (CBF), cerebral blood volume and blood oxygen content. We explored whether NIRS might be a more easy applicable proxy to [15O]H2O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d9ff02098a6f8dc4e1e62f12c58a30
https://research.vumc.nl/en/publications/578a0b63-b8a0-4849-b527-e77a715e188d
https://research.vumc.nl/en/publications/578a0b63-b8a0-4849-b527-e77a715e188d
Autor:
Iněs F. Antunes, Hidde J. Haisma, Philip H. Elsinga, Aren van Waarde, Antoon T.M. Willemsen, Rudi A. Dierckx, Erik F.J. de Vries
Publikováno v:
Molecular Imaging, Vol 11 (2012)
β-Glucuronidase (β-GUS) plays an important role in inflammation and degenerative processes. The enzyme has also been investigated as a target in prodrug therapy for cancer. To investigate the role of β-GUS in pathologies and to optimize β-GUS-bas
Externí odkaz:
https://doaj.org/article/43ed4e65f13b411ab0a307ab8df4aa7a