Zobrazeno 1 - 10
of 96
pro vyhledávání: '"T.L. Nagabhushan"'
Autor:
S.F. Wen, H. Engler, Robert J. Connor, T.L. Nagabhushan, William F. Benedict, P.M. Ihnat, D.C. Maneval
Publikováno v:
Cytokine & Growth Factor Reviews. 18:389-394
Intravesical administration of interferon alpha-2b protein (IFN) has been successfully used in the treatment of patients with superficial bladder tumors. Local dosing of IFN minimizes well-known systemic side effects of the drug, but exposure to blad
Autor:
Machemer T, Bausch J, Suganto Sutjipto, Philopena Jm, McAuliffe Jp, Robert J. Connor, Hindsgaul O, Horn Mt, Youngster S, H. Engler, D.C. Maneval, T.L. Nagabhushan, Chan Tm
Publikováno v:
Gene Therapy. 8:41-48
Adenovirus-mediated gene therapy of bladder diseases has been limited by the inability to transduce the urothelium successfully using adenoviral vectors. We have sought to identify agents that would increase adenovirus-mediated transgene expression i
Publikováno v:
Experimental Cell Research. 251:33-45
The alpha(v)beta(3) integrin mediates endothelial cell binding to the extracellular matrix and transduces an intracellular signal promoting survival of endothelial cells and various tumor cells. While the alpha(v)beta(3) integrin-mediated survival si
Autor:
T.L. Nagabhushan, Duane E. Johnson, Barry J. Sugarman, Wills Ken N, Robert Bookstein, Chulbul M. I. Ahmed, Diganta Saha
Publikováno v:
Human Gene Therapy. 10:77-84
A replication-deficient adenovirus encoding human interferon alpha2b, driven by the human cytomegalovirus (CMV) promoter, was constructed and characterized. This construct was used to infect human cells derived from different types of cancer. The pro
Autor:
T.L. Nagabhushan, G.S.J. Rao, G. Kamer, Barry C. Finzel, Daniel C. Carter, P. P. Trotta, Terry L. Bray, J. Ding, M.A. Navia, K.P. Wilson, Sthanam V.L. Narayana, Michael Harrington, J. Prahl, J.A. Thomson, F.A. Lewandowski, S.H. Hughes, C.J. Meade, B.G. Harris, E.S. Baker, A. D Clark, K.D. Bowersox, L.J. DeLucas, A. Sacco, R.G. Nanni, Eddy Arnold, S.H. Munson, Karen M. Moore, L.L. Clancy, Howard Einspahr, Charles E. Bugg, William M. Rosenblum, A. Jacobo-Molina, Craig D. Smith, Alexander McPherson, Marianna M. Long, P.F. Cook, B.J. Dunbar, S.P. Bishop, Paul Reichert, Mike Carson, R.N. Richards, E. Trinh, P.C. Weber
Publikováno v:
Journal of Crystal Growth. 135:183-195
Protein crystal growth experiments have been performed on 16 space shuttle missions since April, 1985. The initial experiments utilized vapor diffusion crystallization techniques similar to those used in laboratories for earth-based experiments. More
Autor:
M.R. Walter, W.J. Cook, B.G. Zhao, R.P. Cameron, S.E. Ealick, R.L. Walter, P Reichert, T.L. Nagabhushan, P.P. Trotta, C.E. Bugg
Publikováno v:
Journal of Biological Chemistry. 267:20371-20376
Autor:
Duane E. Johnson, T.L. Nagabhushan, Murali Ramachandra, Barry J. Sugarman, John A. Howe, C.M. Iqbal Ahmed, Wills Ken N
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 21(6)
Replication-deficient adenoviruses expressing human interferon-alpha2b (HuIFN-alpha2b) or the hybrid IFN-alpha2alpha1 or those with the secretory signal deleted, whose express is driven by the alpha-fetoprotein (AFP) promoter, were constructed and ch
Autor:
A. Tsarbopoulos, B.N. Pramanik, T.L. Nagabhushan, P.P. Trotta, M.M. Siegel, R. Tsao, V.W. Doelling
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 562:754-755
Publikováno v:
Acta Crystallographica Section A Foundations of Crystallography. 52:C223-C223
Autor:
Stuart W. McCombie, T.L. Nagabhushan
Publikováno v:
Tetrahedron Letters. 28:5395-5398
N-Benzoylcarbamates formed in situ from 2,3-epoxyalcohols and PhCONCO undergo clean N to C-2 cyclisation followed by N to O acyl migration on treatment with catalytic sodium imidazolide or other bases. Subsequent benzoate cleavage (NaOMe) is accompan