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Akademický článek

Changes in NMDA receptor contribution to synaptic transmission in the brain in a rat model of glaucoma

Autor: A.L. Georgiou, L. Guo, M.F. Cordeiro, T.E. Salt

Publikováno v: Neurobiology of Disease, Vol 39, Iss 3, Pp 344-351 (2010)

In the age-related, blinding disease glaucoma, retinal ganglion cells (RGCs) degenerate, possibly affecting glutamatergic retinofugal transmission to the brain. The superior colliculus (SC) is a major central target of retinofugal axons in the rodent

Externí odkaz: https://doaj.org/article/f48e974c993249a2b2e7dc0fd54893e3

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Akademický článek

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Activation of Group II and Group III metabotropic glutamate receptors by endogenous ligand(s) and the modulation of synaptic transmission in the superficial superior colliculus

Autor: T.E. Salt, S.A. Neale, Hannah Thompson

Publikováno v: Neuropharmacology. 47:822-832

Previous work from this laboratory indicates that Group II/III metabotropic glutamate (mGlu) receptors modulate responses of SC neurones to visual stimuli in vivo. It is thought that tonic levels of glutamate may be sufficient to activate some mGlu r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc26b7672dad3a4d945830550d604d3
https://doi.org/10.1016/j.neuropharm.2004.06.019

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Modulation of sensory inhibition in the ventrobasal thalamus via activation of group II metabotropic glutamate receptors by 2 R ,4 R -aminopyrrolidine-2,4-dicarboxylate

Autor: J. P. Turner, T.E. Salt

Publikováno v: Experimental Brain Research. 121:181-185

Recordings were made from single neurones responsive to somatosensory input in the ventrobasal thalamus of the anaesthetised rat. GABAergic afferent inhibition arising from the thalamic reticular nucleus was evoked using a condition-test vibrissal st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd4912faae113b9159fefb36ca8ff31
https://doi.org/10.1007/s002210050450

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Reduction of sensory and metabotropic glutamate receptor responses in the thalamus by the novel metabotropic glutamate receptor-1-selective antagonist S-2-methyl-4-carboxy-phenylglycine

Autor: T.E. Salt, J. P. Turner

Publikováno v: Neuroscience. 85:655-658

Previous work has shown that responses of thalamic neurons in vivo to the metabotropic glutamate receptor agonists 1S,3R-aminocyclopentane-1,3-dicarboxylate and S-3,5-dihydroxyphenylglycine can be reduced by a variety of phenylglycine antagonists. Re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d3f2283b88a8992dd08e498f5d217c
https://doi.org/10.1016/s0306-4522(98)00048-7

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Role of N-methyl-d-aspartate and metabotropic glutamate receptors in corticothalamic excitatory postsynaptic potentials In vivo

Autor: T.E. Salt, S.A. Eaton

Publikováno v: Neuroscience. 73:1-5

The ventrobasal thalamus is the principal somatosensory thalamic relay nucleus, and it receives two major sources of excitatory input: firstly an input from ascending sensory afferents, and secondly a descending projection from the primary somatosens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f040a9c9b638267d53f0c9517ab8e53d
https://doi.org/10.1016/0306-4522(96)00123-6

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Distinct presynaptic metabotropic receptors for l-AP4 and CCG1 on GABAergic terminals: Pharmacological evidence using novel α-methyl derivative mGluR antagonists, MAP4 and MCCG, in the rat thalamus in vivo

Autor: S.A. Eaton, T.E. Salt

Publikováno v: Neuroscience. 65:5-13

A variety of metabotropic excitatory amino acid receptors are present in the thalamus. We have investigated the possibility that some of these receptors may have presynaptic effects on GABAergic inhibitory transmission in the thalamus. Inhibitory res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6550fc8e1b781dd0c09715440bf834
https://doi.org/10.1016/0306-4522(94)00464-g

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Thalamocortical and corticocortical excitatory postsynaptic potentials mediated by excitatory amino acid receptors in the cat motor cortexin vivo

Autor: P.L. Herrling, C.L. Meier, T. Krucker, T.E. Salt, N. Seno

Publikováno v: Neuroscience. 64:433-442

Intracellular recordings were made from neurons in the motor cortex of an anaesthetized cat, together with iontophoretic application of excitatory amino acid receptor agonists and antagonists, in order to evaluate the role of such receptors in excita

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9746b83c1e7302908f20f259cf6bf8a
https://doi.org/10.1016/0306-4522(94)00357-b

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