Hippocampus-dependent fear conditioning is not sensitized by muscarinic receptor activation following systemic injection of pilocarpine

Autor: A.P.R. Costa, Roger Walz, T.C.M. De Lima, Gilliard Lach, Alexandre Ademar Hoeller, Zuner A. Bortolotto

Publikováno v: Hoeller, A A, Lach, G, Costa, A P R, Walz, R, Bortolotto, Z A & De Lima, T C M 2019, ' Hippocampus-dependent fear conditioning is not sensitized by muscarinic receptor activation following systemic injection of pilocarpine ', Neurology Psychiatry and Brain Research, vol. 34, pp. 44-49 . https://doi.org/10.1016/j.npbr.2019.10.004

The regulation of muscarinic acetylcholine receptors (mAChR) critically influences emotional outcomes. Previous researches indicate that a single systemic injection of pilocarpine – a mAChR agonist – displays long-term defensive behaviors in rats

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5e1b259fdd1d204cd63b92cc97ff98
https://hdl.handle.net/1983/61edd1cb-7fca-45ee-b7c6-72a7d85da1c8

Anxiolytic-like, stimulant and neuroprotective effects of Ilex paraguariensis extracts in mice

Autor: A. A. dos Santos, Evelyn Cristina da Silva Santos, Carlos H. Blum-Silva, Maíra A. Bicca, Marcelo Farina, Flávio Henrique Reginatto, A.P.R. Costa, Eloir Paulo Schenkel, T.C.M. De Lima

Publikováno v: Neuroscience. 292:13-21

Yerba-mate (Ilex paraguariensis St. Hil.) is the most used beverage in Latin America with approximately 426 thousand of tons consumed per year. Considering the broad use of this plant, we aimed to investigate the anxiety-like and stimulant activity o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2538343ff6ec436339d5796dd4808a
https://doi.org/10.1016/j.neuroscience.2015.02.004

The anxiolytic-like effects of Aloysia polystachya (Griseb.) Moldenke (Verbenaceae) in mice

Autor: M. A. Campuzano, Sergio Mora, María L. Kennedy, Mariel Marder, Cristina Wasowski, Sebastian P. Fernandez, Y. Montalbetti, M.C. Hellión-Ibarrola, D.A. Ibarrola, O. Heinichen, Jaime Tortoriello, T.C.M. De Lima

Publikováno v: Journal of Ethnopharmacology. 105:400-408

The aim of the present work is to demonstrate the putative sedative and anxiolytic-like effects of a hydro-ethanolic extract obtained from the aerial parts of Aloysia polystachya (Verbenaceae) in male mice using several behavioural assays. Groups of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa213cce5cdf641f3d432a57193cc88
https://doi.org/10.1016/j.jep.2005.11.013

Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test

Autor: Giuliano Marzola, Rosalia Bertorelli, Domenico Regoli, Elaine C. Gavioli, Giles A. Rae, S. Salvadori, Silvia Zucchini, Girolamo Calo, Remo Guerrini, T.C.M. De Lima

Publikováno v: European Journal of Neuroscience. 17:1987-1990

Nociceptin/orphanin FQ (N/OFQ), the endogenous ligand of the NOP receptor, regulates several central functions such as pain transmission, learning and memory, fear and anxiety and feeding and locomotor activity. It has been recently reported that NOP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb112f9bb966f9635de2fbc78f7e99fa
https://doi.org/10.1046/j.1460-9568.2003.02603.x

Behavioural effects of crude and semi-purified extracts ofSyzygium cuminii linn. skeels

Autor: Mareni Rocha Farias, Gina Struffaldi Morato, P. A. Pereira, W. P. Macedo-Neto, T.C.M. De Lima, P. A. Klüeger

Publikováno v: Phytotherapy Research. 12:488-493

In this study, different extracts, fractions and subfractions from the seeds of Syzygium cuminii Linn. Skeels, have been evaluated for behavioural effects in mice, particularly in relation to their sedative and anticonvulsant actions. Oral treatment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ac9eff8423fce3f7bc5b9368704395c
https://doi.org/10.1002/(sici)1099-1573(199811)12:7<488::aid-ptr344>3.0.co