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Modulation of Metallothionein-III mRNA Content and Growth Rate of Rat C6-Glial Cells by Transfection with Human 5-HT1D Receptor Genes

Autor: M.C. Amoureux, T. Wurch, P.J. Pauwels

Publikováno v: Biochemical and Biophysical Research Communications. 214:639-645

The mRNA content of the brain-specific metallothionein-III (MT-III) protein was measured by quantitative reverse transcription-polymerase chain reaction (RT-PCR) in two transformed glial cell lines: rat C6-glial and human U-373 MG cells. Low levels o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988adbc568e971c13fd7f89855cf9de8
https://doi.org/10.1006/bbrc.1995.2334

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Identification of C-terminal amino acid residues of cauliflower mosaic virus open reading frame III protein responsible for its DNA binding activity

Autor: Jean-Luc C. Mougeot, Geneviève Lebeurier, Jean-Michel Mesnard, T. Wurch, Thierry Guidasci

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 1993, 90 (4), pp.1470-3

We cloned in Escherichia coli truncated versions of the protein p15 encoded by open reading frame III of cauliflower mosaic virus. We then compared the ability of the wild-type p15 (129 amino acids) and the deleted p15 to bind viral double-stranded D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9393a39cd79de8a5982a8a3488f0f43c
https://doi.org/10.1073/pnas.90.4.1470

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The cauliflower mosaic virus reverse transcriptase is not produced by the mechanism of ribosomal frameshifting in Saccharomyces cerevisiae

Autor: Thierry Guidasci, Angèle Geldreich, Jean-Michel Mesnard, Geneviève Lebeurier, T. Wurch

Publikováno v: Virology
Virology, Elsevier, 1991, 180 (2), pp.837-41

The capsid protein and the reverse transcriptase of cauliflower mosaic virus (CaMV) are encoded by two genes (ORF IV and ORF V) that lie in different translation reading frames. A comparison can be drawn between the synthesis of both CaMV proteins an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcd33102d8f5d8f6418eae66fcac451
https://doi.org/10.1016/0042-6822(91)90103-i

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Therapeutic antibodies and derivatives: from the bench to the clinic

Autor: A, Beck, T, Wurch, N, Corvaïa

Publikováno v: Current pharmaceutical biotechnology. 9(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7b077e6397147724f9c603f9b2d5113b
https://pubmed.ncbi.nlm.nih.gov/19075681

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Reciprocal modulation of alpha(2A)-adrenoceptor and G(alpha o) protein states as determined by carboxy-terminal mutagenesis of a G(alpha o) protein

Autor: T, Wurch, J, Okuda, P J, Pauwels

Publikováno v: Molecular pharmacology. 60(4)

The C-terminal portion of G(alpha) proteins plays a key role in their selective activation by cognate receptors. alpha(2A)-Adrenoceptors (alpha(2A)-ARs) can differentially inhibit or stimulate adenylyl cyclases by the activation of distinct G(i/o) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7c8e3c74331d9b0e9aa35561816ecd7c
https://pubmed.ncbi.nlm.nih.gov/11562427

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Molecular cloning, pharmacological properties and tissue distribution of the porcine 5-HT(1B) receptor

Autor: P, Bhalla, H S, Sharma, X, Ma, T, Wurch, P J, Pauwels, P R, Saxena

Publikováno v: British journal of pharmacology. 133(6)

Using a combination of RT - PCR and inverse-PCR techniques, we amplified, cloned and sequenced a full-length porcine 5-HT(1B) receptor cDNA derived from porcine cerebral cortex. Sequence analysis revealed 1170 bp encoding an open reading frame of 390

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::62b32d29501f56f6aacb1bab4afb46e2
https://pubmed.ncbi.nlm.nih.gov/11454663

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Dynamic dopamine-antagonist interactions at recombinant human dopamine D(2short) receptor: dopamine-bound versus antagonist-bound receptor states

Autor: P J, Pauwels, F, Finana, S, Tardif, T, Wurch, F C, Colpaert

Publikováno v: The Journal of pharmacology and experimental therapeutics. 297(1)

Antipsychotic drugs comprise a wide range of structurally diverse compounds and are considered to be antagonists at dopamine D2 receptors. High-resolution kinetic analyses of their antagonist properties was performed by monitoring dynamic dopamine (D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f392bf25c0aa7313c485b837def042d4
https://pubmed.ncbi.nlm.nih.gov/11259537

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