Zobrazeno 1 - 10
of 24
pro vyhledávání: '"T. William J. Moorhead"'
Autor:
Anna Peel, James McKirdy, Andrew M. McIntosh, Jeremy Hall, Emma Sprooten, T. William J. Moorhead, Stephen M. Lawrie, Mark E. Bastin, Seonaid M. Anderson, Eve C. Johnstone, Jessika E. Sussmann, Stephen Giles, April Clugston, Allen J. Shand
Publikováno v:
Biological Psychiatry. 70:350-356
Background Bipolar disorder is a familial psychiatric disorder associated with reduced white matter integrity, but it is not clear whether such abnormalities are present in young unaffected relatives and, if so, whether they have behavioral correlate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58137392ca9ea96e141e3cb236ff4564
https://doi.org/10.1016/j.biopsych.2011.01.021
https://doi.org/10.1016/j.biopsych.2011.01.021
Autor:
Jessika E. Sussmann, Dominic Job, Jeremy Hall, Stephen M. Lawrie, Eve C. Johnstone, Andrew M. McIntosh, T. William J. Moorhead, Andrew C. Stanfield, James McKirdy, Stephen Giles
Publikováno v:
Bipolar Disorders. 11:135-144
OBJECTIVES: Abnormalities of ventral prefrontal function have been widely reported in bipolar disorder, but reports of structural abnormalities in the same region are less consistent. We examined the presence and location of ventral prefrontal abnorm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb54846cd981f602a8217f37b786002
https://doi.org/10.1111/j.1399-5618.2009.00666.x
https://doi.org/10.1111/j.1399-5618.2009.00666.x
Autor:
Eve C. Johnstone, Jeremy Hall, T. William J. Moorhead, David G.C. Owens, Benjamin J. Baig, Heather C. Whalley, Dominic Job, Andrew M. McIntosh, Stephen M. Lawrie
Publikováno v:
Biological Psychiatry. 64:428-433
Background Strong evidence exists for an association between genetic variation in the gene DAOA (D-amino acid oxidase activator, also known as G72) and risk for schizophrenia. Preliminary evidence in healthy control subjects has implicated genetic va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1915fe0045df1a69685be14a4308ca3
https://doi.org/10.1016/j.biopsych.2008.03.009
https://doi.org/10.1016/j.biopsych.2008.03.009
Autor:
Andrew C. Stanfield, Eve C. Johnstone, T. William J. Moorhead, Stephen M. Lawrie, Jonathan M. Harris, David G.C. Owens
Publikováno v:
Biological Psychiatry. 63:80-85
Background Two of the strongest predictors of later schizophrenia in the Edinburgh High Risk Study (EHRS) were the presence of schizotypal features and increased right prefrontal lobe cortical folding. We examined the association between these measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b9e51ff1c7ee9a857df26f81189d41
https://doi.org/10.1016/j.biopsych.2007.04.012
https://doi.org/10.1016/j.biopsych.2007.04.012
Autor:
Jeremy Hall, Eve C. Johnstone, Stephen M. Lawrie, T. William J. Moorhead, James McKirdy, Jessika E. Sussmann, Andrew M. McIntosh
Publikováno v:
Biological Psychiatry. 62:894-900
Background Structural brain abnormalities of the medial temporal lobe have been found in people with bipolar disorder (BPD). It is not known whether these abnormalities progress over the course of the illness or how they relate to neuropsychologic fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e7d14f48d09f7d22bf6bce369807c3
https://doi.org/10.1016/j.biopsych.2007.03.005
https://doi.org/10.1016/j.biopsych.2007.03.005
Autor:
Dominic Job, Jeremy Hall, Eve C. Johnstone, Andrew M. McIntosh, David J. Porteous, G. Katherine S. Lymer, Patrick Miller, David G.C. Owens, Ben J. Baig, T. William J. Moorhead, Stephen M. Lawrie, Heather C. Whalley
Publikováno v:
Biological Psychiatry. 61:1127-1134
Background There is growing evidence that the gene catechol-O-methyltransferase (COMT) is involved in the etiopathogenesis of schizophrenia. This study sought to clarify the effects of the COMT Val 158 Met polymorphism on brain structure, function, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6eda2bd7976b7f2939e68b8eef21277
https://doi.org/10.1016/j.biopsych.2006.05.020
https://doi.org/10.1016/j.biopsych.2006.05.020
Autor:
T. William J. Moorhead, Dominic Job, Stephen M. Lawrie, Michael D. Spencer, Heather C. Whalley, Eve C. Johnstone
Publikováno v:
NeuroImage. 28:544-552
We present an empirical comparison of cluster extent and maximal voxel results in a voxel-based morphometry (VBM) study of brain structure. The cluster extents are adjusted for underlying deviation from uniform smoothness. We implement this compariso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936c7fe30f3195610bc026c728220330
https://doi.org/10.1016/j.neuroimage.2005.04.045
https://doi.org/10.1016/j.neuroimage.2005.04.045
White Matter Density in Patients with Schizophrenia, Bipolar Disorder and Their Unaffected Relatives
Autor:
Eve C. Johnstone, Lesley K. Harrison, Stephen M. Lawrie, Andrew M. McIntosh, T. William J. Moorhead, Dominic Job
Publikováno v:
Biological Psychiatry. 58:254-257
Background This study sought to assess white matter density in patients and relatives with histories of bipolar disorder and/or schizophrenia. Methods Subjects included those with schizophrenia from families affected by schizophrenia alone, those wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adaaef43d468a83cf7173ef4ce5fa50
https://doi.org/10.1016/j.biopsych.2005.03.044
https://doi.org/10.1016/j.biopsych.2005.03.044
Autor:
Eve C. Johnstone, Dominic Job, Lesley K. Harrison, Karen Forrester, T. William J. Moorhead, Andrew M. McIntosh, Stephen M. Lawrie
Publikováno v:
Biological Psychiatry. 56:544-552
Background Structural brain abnormalities in schizophrenia are well replicated; many emerge before the onset of illness and are present in relatives who remain well. Structural changes in bipolar disorder are less clearly established. The possibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ed6b0e62af85938ec8deb5068d2ae4
https://doi.org/10.1016/j.biopsych.2004.07.020
https://doi.org/10.1016/j.biopsych.2004.07.020
Autor:
Guy A. Conlon, Jeremy Hall, David C.G. Owens, Martina Papmeyer, Stephen M. Lawrie, T. William J. Moorhead, Daniel Vincenz, Eve C. Johnstone, Annya M. Smyth, Sibylle Honold, Heather C. Whalley, Andrew M. McIntosh, Emma Sprooten, Dominic Job
Publikováno v:
Schizophrenia research. 151(1-3)
BACKGROUND: Schizophrenia is associated with cortical thickness reductions in the brain, but it is unclear whether these are present before illness onset, and to what extent they are driven by genetic factors. METHODS: In the Edinburgh High Risk Stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2178ad5bbc4ce171187d9ce1024a30
https://pubmed.ncbi.nlm.nih.gov/24120958
https://pubmed.ncbi.nlm.nih.gov/24120958