Zobrazeno 1 - 10
of 11
pro vyhledávání: '"T. W. Spithill"'
Autor:
J L Sexton, M C Wilce, T Colin, G L Wijffels, L Salvatore, S Feil, M W Parker, T W Spithill, C A Morrison
Publikováno v:
The Journal of Immunology. 152:1861-1872
The glutathione S-transferases (FhGST) of the liver fluke Fasciola hepatica have been identified as novel vaccine candidates that protect sheep against a fluke infection. With the use of overlapping peptides covering the predicted amino acid sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77f7b2291033b98510b15237795a28b9
https://doi.org/10.4049/jimmunol.152.4.1861
https://doi.org/10.4049/jimmunol.152.4.1861
Publikováno v:
Veterinary parasitology. 154(3-4)
This study reports on the predictive relationship between serological, immunological and pathological responses following experimental inoculation with incremental doses of Fasciola gigantica in sheep. Fifty, 6-month-old, naive Merino wethers were al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8aa8a8b1dfa958701871b244109e76da
https://pubmed.ncbi.nlm.nih.gov/18468797
https://pubmed.ncbi.nlm.nih.gov/18468797
Publikováno v:
Veterinary parasitology. 143(3-4)
This study reports the early biochemical changes in plasma, comparative host-immune responses and parasite recovery data in Merino sheep during the first 10 weeks of infection with Fasciola gigantica and Fasciola hepatica. One group of sheep were uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfa0ed8d86e9255ff753f59536ca0a9e
https://pubmed.ncbi.nlm.nih.gov/17069976
https://pubmed.ncbi.nlm.nih.gov/17069976
Autor:
D, Piedrafita, J C, Parsons, R M, Sandeman, P R, Wood, S E, Estuningsih, S, Partoutomo, T W, Spithill
Publikováno v:
Parasite immunology. 23(9)
Passive intraperitoneal transfer of sera from Fasciola hepatica-infected sheep, cattle or rats can protect naive rats from F. hepatica infection, suggesting a parasite killing mechanism within the peritoneal cavity that is dependent on the presence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1dc6ed6503f942063fa6c5b8f529df5
https://pubmed.ncbi.nlm.nih.gov/11589776
https://pubmed.ncbi.nlm.nih.gov/11589776
Autor:
S. Ruiz, S. Mehandru, Virginia A. Pedicord, T. W. Spithill, C. Cheong, Fatemeh Doustdari, Farnaz Zahedifard, P. Seo, P. Parsi, N. Burdin, Welby Montalvo, Chae Gyu Park, Shanjana Awasthi, Elham Gholami, Ingrid Leiner, F. Dalencon, P. Lagisetty, James P. Allison, S. M. Ralph, B. Rokbi, Rouholah Vahabpour, R. Jayaraj, Barbara Papadopoulou, B. S. Powell, Prachi Vilekar, H. Koh, K. Dynon, N. Pascal, A. Rouholamini Najafabadi, Delaram Doroud, B. Danve, Sima Rafati, P. M. Smooker, D. S. Perlin, Eric G. Pamer, D. Piedrafita, S. Park, J. Choi, Yoonkyung Do, Neda Moradin, Azam Bolhassani, Vibhudutta Awasthi, Alireza Vatanara, Diana Dudziak, R. Grams
Publikováno v:
International Immunology. 22:iii42-iii43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1438f4f3b058452670083a93cf13c473
https://doi.org/10.1093/intimm/dxq312
https://doi.org/10.1093/intimm/dxq312
Publikováno v:
International journal for parasitology. 28(9)
Polymerase chain reaction and cDNA library screening approaches were employed to identify a putative member of the highly conserved family of ATP-binding cassette transport proteins from Fasciola hepatica. At the predicted protein level, the F. hepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17fd6a8e33839641ecb46a1e0921a634
https://pubmed.ncbi.nlm.nih.gov/9770623
https://pubmed.ncbi.nlm.nih.gov/9770623
Publikováno v:
Journal of molecular biology. 273(4)
Glutathione S-transferases (GSTs) represent the major class of detoxifying enzymes from parasitic helminths. As a result, they are candidates for chemotherapeutic and vaccine design. Indeed, GSTs from Fasciola hepatica have been found to be effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1d0edadb22b51bb3eb9a8c44f3c5b10
https://pubmed.ncbi.nlm.nih.gov/9367777
https://pubmed.ncbi.nlm.nih.gov/9367777
Autor:
P J, Murray, T W, Spithill
Publikováno v:
The Journal of biological chemistry. 266(36)
The promastigote surface antigen-2 (PSA-2) complex comprises a group of immunogenic surface antigens linked to the surface of the Leishmania major promastigote with glycosylphosphatidylinositol anchors. The L. major genome contains at least 14 PSA-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5611956e34d3f6b5cbbff552decb44e6
https://pubmed.ncbi.nlm.nih.gov/1761547
https://pubmed.ncbi.nlm.nih.gov/1761547
Publikováno v:
The Journal of Immunology. 137:3608-3613
Infection of macrophages by the intracellular protozoan parasite Leishmania involves specific attachment to the host membrane, followed by phagocytosis and intracellular survival and growth. Two parasite molecules have been implicated in the attachme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cc1f5c7b34a7ac06f6d672d919b28cb
https://doi.org/10.4049/jimmunol.137.11.3608
https://doi.org/10.4049/jimmunol.137.11.3608
Publikováno v:
The Journal of Immunology. 143:4221-4226
Polyclonal rabbit antiserum to the Triton X-114 phase material of Leishmania major, which comprises the surface and internal integral membrane proteins of the parasite, was used to screen a lambda gt11 genomic expression library. A recombinant clone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67b4d0d79007c006a927a0e84e4a4b92
https://doi.org/10.4049/jimmunol.143.12.4221
https://doi.org/10.4049/jimmunol.143.12.4221