Zobrazeno 1 - 7
of 7
pro vyhledávání: '"T. W. Cunningham"'
Publikováno v:
The Journal of biological chemistry. 265(35)
We have identified the structure of phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) in human platelets. These lipids accounted for les
Publikováno v:
Biochemical and Biophysical Research Communications. 154:746-751
In formyl peptide stimulated human neutrophils the enhancement of O2 • responses by ATP and ATPγS requires extracellular calcium. In contrast, the inhibitory effects of adenosine are independent of a calcium requirement. Rates of O2 • generation
Publikováno v:
Clinical Immunology and Immunopathology. 50:30-41
When rat neutrophils were stimulated with chemotactic peptide N-formyl-Met-Leu-Phe; fMLP), phorbol myristate acetate (PMA), or immune complexes in the presence of homologous platelets, O2- responses were enhanced. Secretion products of thrombin-stimu
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 58(4)
Our recent studies have indicated that release of ATP/ADP from platelets causes enhanced O2-. responses in stimulated neutrophils. The current investigations were designed to provide further details of this phenomenon, to determine the structure-func
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 58(1)
Human neutrophils stimulated with immune complexes in the presence of platelets show enhanced superoxide anion (O2-.) responses that are proportional to the amount of agonist present and the number of platelets added. Platelet related enhancement of
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 61(5)
Recent evidence suggests that the adenine compounds ATP, adenosine-5'-O-(3-thiotriphosphate) (ATP gamma S), and adenosine have important regulatory effects on O2- responses of human neutrophils stimulated with the chemotactic peptide N-formyl-Met-Leu
Publikováno v:
The Journal of biological chemistry. 264(26)
Epidermal growth factor (EGF) stimulates the turnover of phosphoinositides in A431 cells. In cells that were pretreated with EGF for 30 min at 37 degrees C and then washed to remove surface-bound hormone, a 70-100% decrease in the EGF-stimulated prod