Zobrazeno 1 - 10
of 209
pro vyhledávání: '"T. Vaara"'
Autor:
Maija Serlo, Nina Inkinen, Päivi Lakkisto, Miia Valkonen, Anni Pulkkinen, Tuomas Selander, Ville Pettilä, Suvi T. Vaara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Fluid therapy is a fundamental part of supportive therapy in critical care. However, it is also a suspected risk for endothelial glycocalyx degradation which is associated with poor clinical outcomes. This secondary analysis of RESPONSE rand
Externí odkaz:
https://doaj.org/article/26252bb2873744b7b51c051582aee3c8
Autor:
Johanna Laurikkala, Koen Ameloot, Matti Reinikainen, Pieter-Jan Palmers, Cathy De Deyne, Ferdinande Bert, Matthias Dupont, Stefan Janssens, Joseph Dens, Johanna Hästbacka, Pekka Jakkula, Pekka Loisa, Thomas Birkelund, Erika Wilkman, Suvi T. Vaara, Markus B. Skrifvars
Publikováno v:
Annals of Intensive Care, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Background We aimed to study the incidence of acute kidney injury (AKI) in out-of-hospital cardiac arrest (OHCA) patients treated according to low-normal or high-normal mean arterial pressure (MAP) targets. Methods A post hoc analysis of the
Externí odkaz:
https://doaj.org/article/1d512b04ac294baba2e4045e11894b29
Autor:
Erik Hartman, Aaron M. Scott, Christofer Karlsson, Tirthankar Mohanty, Suvi T. Vaara, Adam Linder, Lars Malmström, Johan Malmström
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The incorporation of machine learning methods into proteomics workflows improves the identification of disease-relevant biomarkers and biological pathways. However, machine learning models, such as deep neural networks, typically suffer from
Externí odkaz:
https://doaj.org/article/6ba2704448034c108462da0c1d21a25d
Autor:
Aaron M. Scott, Christofer Karlsson, Tirthankar Mohanty, Erik Hartman, Suvi T. Vaara, Adam Linder, Johan Malmström, Lars Malmström
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Data independent acquisition mass spectrometry (DIA-MS) has recently emerged as an important method for the identification of blood-based biomarkers. However, the large search space required to identify novel biomarkers from the plasma prote
Externí odkaz:
https://doaj.org/article/c62f01db96f746e9960e9d6a3d365a00
Autor:
Suvi T. Vaara, MD, PhD, Ary Serpa Neto, MD, PhD, Rinaldo Bellomo, MD, PhD, Neill K. J. Adhikari, MDCM, MSc, Didier Dreyfuss, MD, PhD, Martin Gallagher, MD, PhD, Stephane Gaudry, MD, PhD, Eric Hoste, MD, PhD, Michael Joannidis, MD, Ville Pettilä, MD, PhD, Amanda Y. Wang, MD, PhD, Kianoush Kashani, MD, PhD, Ron Wald, MDCM, MPH, Sean M. Bagshaw, MD, MSc, Marlies Ostermann, MD, PhD, Sean M Bagshaw
Publikováno v:
Critical Care Explorations, Vol 6, Iss 2, p e1053 (2024)
OBJECTIVES:. Among patients with severe acute kidney injury (AKI) admitted to the ICU in high-income countries, regional practice variations for fluid balance (FB) management, timing, and choice of renal replacement therapy (RRT) modality may be sign
Externí odkaz:
https://doaj.org/article/2a1c155b95d6476f912d3bab80f84a29
Autor:
Nina Inkinen, Ville Pettilä, Miia Valkonen, Maija Serlo, Minna Bäcklund, Johanna Hästbacka, Anni Pulkkinen, Tuomas Selander, Suvi T. Vaara
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-10 (2022)
Abstract Background Fluid bolus therapy is a common intervention to improve urine output. Data concerning the effect of a fluid bolus on oliguria originate mainly from observational studies and remain controversial regarding the actual benefit of suc
Externí odkaz:
https://doaj.org/article/8b21979fb53441a3ba2e61038f8247fb
Autor:
Ron Wald, Brian Kirkham, Bruno R. daCosta, Ehsan Ghamarian, Neill K. J. Adhikari, William Beaubien-Souligny, Rinaldo Bellomo, Martin P. Gallagher, Stuart Goldstein, Eric A. J. Hoste, Kathleen D. Liu, Javier A. Neyra, Marlies Ostermann, Paul M. Palevsky, Antoine Schneider, Suvi T. Vaara, Sean M. Bagshaw
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-11 (2022)
Abstract Background Among critically ill patients with acute kidney injury (AKI), earlier initiation of renal replacement therapy (RRT) may mitigate fluid accumulation and confer better outcomes among individuals with greater fluid overload at random
Externí odkaz:
https://doaj.org/article/b9edb07f083f4e9dba7a9cf8ec2cafaf
Autor:
Suvi T. Vaara, Pavan K. Bhatraju, Natalja L. Stanski, Blaithin A. McMahon, Kathleen Liu, Michael Joannidis, Sean M. Bagshaw
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-10 (2022)
Abstract Acute kidney injury (AKI) is a frequently encountered syndrome especially among the critically ill. Current diagnosis of AKI is based on acute deterioration of kidney function, indicated by an increase in creatinine and/or reduced urine outp
Externí odkaz:
https://doaj.org/article/6afba74140cf4e3d989512575e0af1f1
Autor:
Fernando G. Zampieri, Bruno R. da Costa, Suvi T. Vaara, François Lamontagne, Bram Rochwerg, Alistair D. Nichol, Shay McGuinness, Danny F. McAuley, Marlies Ostermann, Ron Wald, Sean M. Bagshaw, STARRT-AKI Investigators
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-10 (2022)
Abstract Background Timing of initiation of kidney-replacement therapy (KRT) in critically ill patients remains controversial. The Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial compared
Externí odkaz:
https://doaj.org/article/6c0c4db9732b407e92ad962eefa9c5f5
Autor:
Eric A. Hoste, Suvi T. Vaara, Jorien De Loor, Mikko Haapio, Lieve Nuytinck, Kristel Demeyere, Ville Pettilä, Evelyne Meyer, The FINNAKI Study Group
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-10 (2020)
Abstract Background Acute kidney injury (AKI) is a frequently occurring syndrome in critically ill patients and is associated with worse outcomes. Biomarkers allow early identification and therapy of AKI which may improve outcomes. Urine chitinase 3-
Externí odkaz:
https://doaj.org/article/1472af90bd3640ccaf266ec78a96454b