Zobrazeno 1 - 10
of 28
pro vyhledávání: '"T. V. Ton"'
Autor:
Bruce Alex Merrick, Grace E. Kissling, Esra Mutlu, Amy E. Brix, Arun R. Pandiri, T. V. Ton, Helen Cunny, Suramya Waidyanatha, Hue-Hua L. Hong, Michael J. DeVito, Leslie Recio, Suzanne L. Phillips, Timothy Maynor, Robert C. Sills, June K. Dunnick
Publikováno v:
Toxicology Reports, Vol 5, Iss, Pp 615-624 (2018)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • Pentabrominated diphenyl ether (PBDE) mixture was a multispecies carcinogen causing liver tumors in male and female rats and mice. • Hras or Ctnnb1 mutations characterized the PBDE-induced liver tumors. • PB
Highlights • Pentabrominated diphenyl ether (PBDE) mixture was a multispecies carcinogen causing liver tumors in male and female rats and mice. • Hras or Ctnnb1 mutations characterized the PBDE-induced liver tumors. • PB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266f307cb8f0fdcb8710fda714a500b8
https://doi.org/10.1016/j.toxrep.2018.05.010
https://doi.org/10.1016/j.toxrep.2018.05.010
Autor:
Keith R. Shockley, Kevin Gerrish, Arun R. Pandiri, Susan A. Elmore, Daniel L. Morgan, T. V. Ton, B.A. Merrick, June K. Dunnick
Publikováno v:
Toxicology Letters. 266:32-41
Tetrabromobisphenol A (TBBPA) is a widely used flame retardant in printed circuit boards, paper, and textiles. In a two-year study, TBBPA showed evidence of uterine tumors in female Wistar-Han rats and liver and colon tumors in B6C3F1 mice. In order
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967644d1ce8ae1d135f6a8a00f8f176c
https://doi.org/10.1016/j.toxlet.2016.11.019
https://doi.org/10.1016/j.toxlet.2016.11.019
Autor:
J. Michael Sanders, T. V. Ton, Daniel L. Morgan, Kevin Gerrish, Gregory S. Travlos, Arun R. Pandiri, June K. Dunnick, Keith R. Shockley, Amy Brix
Publikováno v:
Archives of Toxicology. 91:1685-1696
N,N-dimethyl-p-toluidine (DMPT), an accelerant for methyl methacrylate monomers in medical devices, was a liver carcinogen in male and female F344/N rats and B6C3F1 mice in a 2-year oral exposure study. p-Toluidine, a structurally-related chemical, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a432c141722abc62c3cbf66e79f82c1
https://doi.org/10.1007/s00204-016-1831-7
https://doi.org/10.1007/s00204-016-1831-7
Autor:
Kevin Gerrish, Robert C. Sills, Keith R. Shockley, Tiwanda Masinde, Shyamal D. Peddada, Stephanie A. Lahousse, Hu Hua Hong, Scott S. Auerbach, T. V. Ton, Mark J. Hoenerhoff, Arun R. Pandiri, Pierre R. Bushel
Publikováno v:
Toxicologic Pathology. 39:678-699
Hepatocellular carcinoma (HCC) is an important cause of morbidity and mortality worldwide. Although the risk factors of human HCC are well known, the molecular pathogenesis of this disease is complex, and in general, treatment options remain poor. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d07f7da5edf8607082fc538394e17d7
https://doi.org/10.1177/0192623311407213
https://doi.org/10.1177/0192623311407213
Publikováno v:
Toxicologic Pathology. 37:835-848
Tumor response in the B6C3F1 mouse, F344 rat, and other animal models following exposure to various compounds provides evidence that people exposed to these or similar compounds may be at risk for developing cancer. Although tumors in rodents and hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6166d4febec3ed431345dc27002b67c9
https://doi.org/10.1177/0192623309351726
https://doi.org/10.1177/0192623309351726
Autor:
T. V. Ton, Mark J. Hoenerhoff, Susan A. Elmore, Janice B. Harvey, Tiwanda Masinde, Shyamal D. Peddada, Sachin Bhusari, June K. Dunnick, Hue-Hua L. Hong, Arun R. Pandiri, Tanasa S. Osborne
Endometrial carcinoma is the most common gynecologic malignancy is the United States and accounts for 6% of all cancers in women. The disease is classified as type I or type II based on clinicopathologic and molecular features. It is a multifactorial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff674cf5830522fc0b6a32342c95659
https://europepmc.org/articles/PMC4670270/
https://europepmc.org/articles/PMC4670270/
Autor:
Natasha P. Clayton, June K. Dunnick, Po-Chuen Chan, Cindy R. Moomaw, Theodora R. Devereux, Robert C. Sills, T. V. Ton, Hue-Hua L. Hong
Publikováno v:
Toxicology and Applied Pharmacology. 191:227-234
The most prominent neoplastic lesions in mice in the 2-year studies of o -nitrotoluene and riddelliine were hemangiosarcomas. Fifteen o -nitrotoluene-induced hemangiosarcomas of the skeletal muscle, subcutaneous tissue, and mesentery; 12 riddelliine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f52dcafe113cdc00f11f8d3e583181
https://doi.org/10.1016/s0041-008x(03)00165-0
https://doi.org/10.1016/s0041-008x(03)00165-0
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