Zobrazeno 1 - 10
of 29
pro vyhledávání: '"T. V. Osadchuk"'
Autor:
T. V. Osadchuk, V. K. Kibirev1,2,, O. V. Shybyryn, A. V. Semyroz, Ye. S. Velihina, Е. R. Abdurakhmanova, V. S. Brovarets
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 4, Pp 5-16 (2019)
A series of novel triphenylphosphonium derivatives of 1,3-oxazole containing at C2 and C5-positions electron withdrawing or electron-donating groups were synthesized and characterized by 1H, 31P NMR and IR spectroscopy, element analysis and chromato-
Externí odkaz:
https://doaj.org/article/2299252c229f477c84e47ae369ef9495
Publikováno v:
The Ukrainian Biochemical Journal, Vol 90, Iss 5, Pp 28-33 (2018)
Furin belongs to a family of calcium-dependent serine proprotein convertases, which transform the inactive protein precursors into mature polypeptides. In model experiments, we studied the effect of organic solvents such as acetone, dimethyl sulfoxid
Externí odkaz:
https://doaj.org/article/5a41a16bb75c484f8b5d1d2195dafd3a
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 6, Pp 3-12 (2017)
The proprotein convertase furin plays a crucial role in a variety of pathogenic processes such as cancer, bacterial and viral diseases, neurodegenerative disorders and diabetes. Thus, furin inhibitors are promising therapeutics for the treatment of
Externí odkaz:
https://doaj.org/article/b4730ca19f0949daae19f92751b940bd
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 5, Pp 15-20 (2017)
Furin is the most studied proprotein convertase which processes inactive protein precursors, converting them into biologically active polypeptides. We have investigated cation effects of cesium, strontium, cadmium, iron, cobalt and nickel on the furi
Externí odkaz:
https://doaj.org/article/2156249f7ba44af09da595aa0d94ed79
Publikováno v:
The Ukrainian Biochemical Journal, Vol 88, Iss 6, Pp 5-25 (2016)
The review is devoted to the analysis of the relationship between a chemical structure and properties of low-molecular weight inhibitors of furin, the most studied proprotein convertase, which is involved in the development of some pathologies, such
Externí odkaz:
https://doaj.org/article/19f14df485474369acbe602840c4304c
Autor:
V. K. Kibirev, T. V. Osadchuk, O. P. Kozachenko, V. Kholodovych, O. D. Fedoryak, V. S. Brovarets
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 1, Pp 55-63 (2015)
A series of novel non-peptidic furin inhibitors with values of inhibitory constants (Ki) in the range of 0.74-1.54 μM was obtained by interactions of aminoguanidine hydrocarbonate with three diaryldicarbaldehydes. Correspondingly p-hydroquinone, pip
Externí odkaz:
https://doaj.org/article/3fb683d48cae4fb3b3c82b31e695f23e
Publikováno v:
The Ukrainian Biochemical Journal, Vol 85, Iss 1, Pp 22-32 (2013)
A series of novel non-peptidic furin inhibitors containing amidinohydrazone moieties has been synthesized under interaction of dialdehydes, the derivatives of ethylene diethylvanillin ethers, with aminoguanidine bicarbonate. Two aryl cycles were brid
Externí odkaz:
https://doaj.org/article/8507eba8fb734d6f92271690c9a407d9
Publikováno v:
INFORMATION TECHNOLOGIES AND MANAGEMENT IN HIGHER EDUCATION AND SCIENCES. PART 1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d2526ad63614b2513c6a28ef6c2162d
https://doi.org/10.30525/978-9934-26-277-7-54
https://doi.org/10.30525/978-9934-26-277-7-54
Publikováno v:
Ukrainian Biochemical Journal, Vol 90, Iss 5, Pp 28-33 (2018)
Furin belongs to a family of calcium-dependent serine proprotein convertases, which transform the inactive protein precursors into mature polypeptides. In model experiments, we studied the effect of organic solvents such as acetone, dimethyl sulfoxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eff32e318701252bfce95a3d3ed0d36
http://ukrbiochemjournal.org/2018/09/influence-of-organic-solvents-on-the-furin-activity.html
http://ukrbiochemjournal.org/2018/09/influence-of-organic-solvents-on-the-furin-activity.html
Publikováno v:
Ukrainian Biochemical Journal, Vol 88, Iss 6, Pp 5-25 (2016)
The review is devoted to the analysis of the relationship between a chemical structure and properties of low-molecular weight inhibitors of furin, the most studied proprotein convertase, which is involved in the development of some pathologies, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a481cb17f2448073a181e9797f789a
https://doi.org/10.15407/ubj88.06.005
https://doi.org/10.15407/ubj88.06.005