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Akademický článek

Evaluation of an online-based self-help program for patients with generalized anxiety disorder - A randomized controlled trial

Autor: J. Rubel, T. Väth, S. Hanraths, L. Pruessner, C. Timm, S. Hartmann, S. Barnow, C. Lalk

Publikováno v: Internet Interventions, Vol 35, Iss , Pp 100716- (2024)

Objectives: This study aimed to evaluate the effects of an online self-help intervention for generalized anxiety disorder (GAD). Our primary outcomes were generalized anxiety symptoms, measured using the Generalized Anxiety Disorder – 7 (GAD-7; Spi

Externí odkaz: https://doaj.org/article/f18f66ebc14d4363b09b17825488483d

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Rapid determination of nevirapine in human plasma by gas chromatography

Autor: Peter Langmann, Hartwig Klinker, Michael Zilly, Desch S, Diana Schirmer, T Väth

Publikováno v: Journal of Chromatography B. 767:69-74

A sensitive and rapid gas chromatographic method has been developed to determine the levels of the HIV-1 non-nucleoside reverse transcriptase inhibitor nevirapine in human plasma. Quantitative recovery following liquid-liquid-extraction with diethyle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b684db10a08a5b740fe322c635956ed
https://doi.org/10.1016/s0378-4347(01)00528-x

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Efavirenz plasma levels for the prediction of treatment failure in heavily pretreated HIV-1 infected patients

Autor: P, Langmann, B, Weissbrich, S, Desch, T, Väth, D, Schirmer, M, Zilly, H, Klinker

Publikováno v: European journal of medical research. 7(7)

Efavirenz (EFV) plasma levels have been discussed as a predictor of treatment failure in HIV infected patients. The aim of this prospective, open-labeled, case-control study was to evaluate pretreated patients in regards to efavirenz plasma levels an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::75ce42f8387dd3724013daa31b3dda13
https://pubmed.ncbi.nlm.nih.gov/12176680

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Triple antiviral re-therapy for chronic hepatitis C with interferon-alpha, ribavirin and amantadine in nonresponders to interferon-alpha and ribavirin

Autor: M, Zilly, C, Lingenauber, S, Desch, T, Väth, H, Klinker, P, Langmann

Publikováno v: European journal of medical research. 7(4)

Therapy options for patients with chronic hepatitis C who failed prior treatment are needed. In recent studies triple antiviral therapy with Interferon-alpha, ribavirin, and amantadine seemed to increase sustained virological response rates in this g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3b3f2f15a63709bcd6b9137761fd2ac4
https://pubmed.ncbi.nlm.nih.gov/12010649

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Therapeutic drug monitoring of indinavir in HIV-infected patients undergoing HAART

Autor: Michael Zilly, Benedikt Weissbrich, Hartwig Klinker, Desch S, P Langmann, T Väth

Publikováno v: Infection. 30(1)

Background: Therapeutic drug monitoring (TDM) of protease inhibitors (PI) is gaining increasing importance for the management of HIV-infected patients undergoing highly active antiretroviral therapy (HAART). The PI indinavir (IDV) is widely used in H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943b90692d3fcd6dcb5d2b8e7f370161
https://pubmed.ncbi.nlm.nih.gov/11876509

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Influence of smoking on cotinine and caffeine plasma levels in patients with alcoholic liver cirrhosis

Autor: P, Langmann, A, Bienert, M, Zilly, T, Väth, E, Richter, H, Klinker

Publikováno v: European journal of medical research. 5(5)

Retention of caffeine was observed in patients with alcoholic liver cirrhosis and impaired liver function. Cotinine, the major metabolite of nicotine, is transformed by microsomal N-oxidation to secondary metabolites. The aim of this study was to inv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c482ce37d9f62b205dac1211af7f7712
https://pubmed.ncbi.nlm.nih.gov/10806124

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Therapeutic drug monitoring of saquinavir in patients during protease inhibitor therapy with saquinavir alone or in combination with ritonavir or nelfinavir

Autor: P, Langmann, M, Zilly, B, Weissbrich, C, Schlör, T, Väth, E, Richter, H, Klinker

Publikováno v: European journal of medical research. 5(2)

Therapeutic drug monitoring is essential in HIV-patients undergoing highly active antiretroviral therapy (HAART). Saquinavir (SQV) is used alone or in combination with ritonavir (RTV) or nelfinavir (NLF), respectively, in the context of the HAART dru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e956000feea967d0be43d600e8b82e5a
https://pubmed.ncbi.nlm.nih.gov/10720564

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