Zobrazeno 1 - 10
of 29
pro vyhledávání: '"T. Trefor Howarth"'
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :1369-1376
The Wittig reaction of phosphoranes and phosphonates with the carbonyl function of mono- and bicyclic β-lactams has been studied and the influence of phosphorane and β-lactam reactivities on the outcome of the reaction noted. The utility and genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d6c677f3c0b47970efe7b895bbd8b13
https://doi.org/10.1039/p19870001369
https://doi.org/10.1039/p19870001369
Publikováno v:
Tetrahedron Letters. 24:2693-2696
Investigation into the chemistry of benzyl clavulanate under a variety of reaction conditions has led to acid catalysed one-step conversion to ether and thioether derivatives. Generation of nitrogen-containing displacement products proceeds via the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14f8dafd95521a1ef9e65a26468bea1d
https://doi.org/10.1016/s0040-4039(00)87979-4
https://doi.org/10.1016/s0040-4039(00)87979-4
Publikováno v:
Tetrahedron. 39:2551-2562
MM 13902, a β-lactam antibiotic isolated from Streptomyces olivaceus, has been identified as (5R6R)- 3- [(E)- 2- acetamidoethenylthio]- 6- [(S)- 1- hydroxysulphonyloxyethyl]- 7- oxo- 1- azabicyclo [3.2.0] hept- 2- ene- 2- carboxylic acid (2) by chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9d73bbcde4efbc6bf0feb2196e90666
https://doi.org/10.1016/s0040-4020(01)92148-9
https://doi.org/10.1016/s0040-4020(01)92148-9
Autor:
T. Trefor Howarth, J.Sydney Davies
Publikováno v:
Tetrahedron Letters. 23:3109-3112
The methanolysis of clavulanic acid (2) and subsequent base catalysed rearrangement to 3, 4-disubstituted pyrroles is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b0faceabfd17ff8e7271d31031edbf9
https://doi.org/10.1016/s0040-4039(00)87546-2
https://doi.org/10.1016/s0040-4039(00)87546-2
Publikováno v:
Journal of the American Chemical Society. 93:2511-2515
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e7376596c36044af496daae4bfaa455
https://doi.org/10.1021/ja00739a025
https://doi.org/10.1021/ja00739a025
Autor:
Thomas M. Harris, T. Trefor Howarth
Publikováno v:
Canadian Journal of Chemistry. 46:3739-3742
Methyl 2-hydroxy-4-methoxy-6-phenylbenzoate (3b) was synthesized by treatment of methyl 6-phenyl-β-resorcylate (3a) with diazomethane. 5-Phenylresorcinol (8) was carboxylated in a Kolbe–Schmitt reaction to give γ-resorcylic acid 7b. Treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a7ad83e67088869d6eed51ba243e7d4
https://doi.org/10.1139/v68-618
https://doi.org/10.1139/v68-618
Autor:
T. Trefor Howarth, Thomas M. Harris
Publikováno v:
Journal of the American Chemical Society. 93:2506-2510
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2855b6193c3206ca2c606a49aee35be3
https://doi.org/10.1021/ja00739a024
https://doi.org/10.1021/ja00739a024
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :490-501
Various attempts to synthesise β-keto-esters of pyrroles for use as model compounds, or as intermediates in chlorophyll synthesis, are described. Carboxylation of acetylpyrroles, using dialkyl carbonates or chloroformates, gave a variety of products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9421b45e8f753c831bc385d4993dba98
https://doi.org/10.1039/p19740000490
https://doi.org/10.1039/p19740000490
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :512-516
Porphyrin carboxylic acids are converted into the corresponding β-keto-esters by reaction between the acid chlorides and t-butyl methyl malonate, followed by treatment with trifluoroacetic acid. Iodine in methanol reacts with the magnesium chelate o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c92a6c969b340b22aabaf3f693e9ca4a
https://doi.org/10.1039/p19740000512
https://doi.org/10.1039/p19740000512
Publikováno v:
J. Chem. Soc., Chem. Commun.. :523-525
The structures of two new, naturally occurring β-lactams are proposed on the basis of spectroscopic properties, and their interconversion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bda3e74b61557d4d4ee2f94a6cf3e2e
https://doi.org/10.1039/c39770000523
https://doi.org/10.1039/c39770000523