In vitro pharmacology of clinically used central nervous system-active drugs as inverse H(1) receptor agonists

Autor: Ethan S. Burstein, Remko A. Bakker, M. W. Nicholas, Rob Leurs, Mark R. Brann, D. M. Weiner, Uli Hacksell, T. T. Smith, Henk Timmerman

Publikováno v: Bakker, R A, Nicholas, M W, Smith, T F, Burstein, E S, Hacksell, U, Timmerman, H, Leurs, R, Brann, M R & Weiner, D M 2007, ' In vitro pharmacology of clinically used central nervous system-active drugs as inverse H(1) receptor agonists ', The Journal of Pharmacology and Experimental Therapeutics, vol. 322, no. 1, pp. 172-9 . https://doi.org/10.1124/jpet.106.118869
The Journal of Pharmacology and Experimental Therapeutics, 322(1), 172-9. American Society for Pharmacology and Experimental Therapeutics

The human histamine H(1) receptor (H(1)R) is a prototypical G protein-coupled receptor and an important, well characterized target for the development of antagonists to treat allergic conditions. Many neuropsychiatric drugs are also known to potently

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f61bfb408dddf44d5a6995354daa9d
https://research.vu.nl/en/publications/66c7d799-6746-4d9c-85af-d71d82b8e32f

Squamous cell carcinoma of the breast following silicone injection of the breasts

Autor: L F, Smith, T T, Smith, E, Yeary, J M, McGee, K, Malnar

Publikováno v: The Journal of the Oklahoma State Medical Association. 92(3)

During the 1960s, injecting liquid silicone into the breasts for augmentation purposes was a common practice. Many women suffered complications, usually developing silicone mastopathy, but there have been reports of carcinoma as well. A case of squam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::40f6fe39d579b25a6ea0742b9a161322
https://pubmed.ncbi.nlm.nih.gov/10087675

The use of iodixanol as a density gradient material for separating human sperm from semen

Autor: W Whitford, T T Smith, D Kaftani, M Byers

Publikováno v: Archives of andrology. 38(3)

Iodixanol, a new nonionic density gradient material with relatively low osmolality and high density, was evaluated to determine its suitability for the separation of human sperm from semen for their subsequent therapeutic use. Using a three-layer iod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950b35bd82f21c84468744e8c9aa367a
https://pubmed.ncbi.nlm.nih.gov/9140619

Role of direct contact between spermatozoa and oviductal epithelial cells in maintaining rabbit sperm viability

Autor: T T, Smith, W B, Nothnick

Publikováno v: Biology of reproduction. 56(1)

In many species, including the rabbit, spermatozoa attach to the apical plasma membrane of oviductal epithelial cells. Attachment to oviductal epithelial cells has a beneficial effect on the maintenance of sperm viability during storage in the oviduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::32c2366241258ac13a7b834d398160ba
https://pubmed.ncbi.nlm.nih.gov/9002636

The viability of hamster spermatozoa stored in the isthmus of the oviduct: the importance of sperm-epithelium contact for sperm survival

Autor: T T, Smith, R, Yanagimachi

Publikováno v: Biology of reproduction. 42(3)

When hamsters mate shortly after the onset of estrus, spermatozoa are stored in the lower oviduct (isthmus) during the preovulatory period. The present study was performed to determine what proportion of the spermatozoa in the isthmus survive until f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::564e3a3b4a0219bcb6dcca912ea3099e
https://pubmed.ncbi.nlm.nih.gov/2340331