Zobrazeno 1 - 10
of 151
pro vyhledávání: '"T. T. MACDONALD"'
Autor:
N, Garrido-Mesa, J-H, Schroeder, E, Stolarczyk, A L, Gallagher, J W, Lo, C, Bailey, L, Campbell, V, Sexl, T T, MacDonald, J K, Howard, R K, Grencis, N, Powell, G M, Lord
Publikováno v:
Mucosal immunology
Innate lymphoid cells (ILCs) play an important role in regulating immune responses at mucosal surfaces. The transcription factor T-bet is crucial for the function of ILC1s and NCR+ ILC3s and constitutive deletion of T-bet prevents the development of
Publikováno v:
Clinical & Experimental Allergy. 33:615-623
Summary Background Food antigens from the maternal circulation may sensitize fetal T cells in utero and be an important determinant in the development of food allergy. Methods Here we have examined the spontaneous and recall response to cow's milk pr
Autor:
Sylvia L.F. Pender, J. A. W. Smith, R. B. Heuschkel, Mona Bajaj-Elliott, T T MacDonald, Giovanni Monteleone
Publikováno v:
Gut. 47:57-62
BACKGROUND—Degradation of the extracellular matrix and ulceration of the mucosa are major features of inflammatory bowel disease (IBD). One of the most important enzymes in degrading the matrix and produced in excess by cytokine activated stromal c
Autor:
R. CARUSO, D. FINA, I. PELUSO, M. C. FANTINI, C. TOSTI, G. DEL VECCHIO BLANCO, O. A. PAOLUZI, F. CAPRIOLI, F. ANDREI, C. STOLFI, V. RICCI, T. T. MACDONALD, F. PALLONE, G. MONTELEONE, ROMANO, Marco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3977::acf2287f84cfc5cdab7e837100ff8e8c
http://hdl.handle.net/11591/181709
http://hdl.handle.net/11591/181709
Publikováno v:
Journal of Clinical Investigation. 102:1473-1480
Immune reactions in the gut are associated with increased epithelial cell proliferation. Here we have studied the role of keratinocyte growth factor (KGF; FGF7) and transforming growth factor-alpha (TGF-alpha) in the epithelial cell hyperplasia seen
Publikováno v:
The Journal of Immunology. 158:1582-1590
Activated lamina propria T cells responding to luminal Ags are thought to be important in celiac disease and Crohn's disease, and T cells responding to foreign MHC products are also important in intestinal graft-vs-host disease and intestinal transpl
Publikováno v:
Clinical and Experimental Immunology. 104:280-285
SUMMARY T cell hypersensitivity has been implicated in the tissue damage in Crohn’s disease (CD). All studies to date have examined mucosal T cells, although much of the tissue damage occurs in the submucosa and muscle layers. The aim of this work
Autor:
T. T. Macdonald
Publikováno v:
Clinical Experimental Allergy. 25:10-13
Autor:
M Y Choy, S. H. Murch, Jo Spencer, Donald A. P. Bundy, Edward Cooper, S. Venugopal, T T MacDonald
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 88:265-268
Mucosal macrophages and accessory cells have been studied by immunohistochemistry in the lamina propria of the colon of children with Trichuris trichiura dysentery syndrome (TDS). No difference was found in the numbers of cells recognized by the mono
Publikováno v:
The Lancet. 341:711-714
We have studied the distribution and nature of sulphated glycosaminoglycans (GAGs) within normal and inflamed intestine. There is increasing evidence that these negatively charged polysaccharides, which both regulate the ability of albumin to leave t