Zobrazeno 1 - 10 of 70 pro vyhledávání: '"T. Shinnick"'
1
Structural requirements of peptide and MHC for DR(alpha, beta 1*0401)-restricted T cell antigen recognition
Autor: J M McNicholl, W C Whitworth, F Oftung, X Fu, T Shinnick, P E Jensen, M Simon, R M Wohlhueter, R W Karr
Publikováno v: The Journal of Immunology. 155:1951-1963
We identified functionally important regions of the DR(alpha, beta 1*0401) peptide binding site and present a model of bound peptide. DR(alpha, beta 1*0401)-restricted T cell recognition and peptide binding of Mycobacterium leprae (ML) peptide 38-50
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21f3ff70177ac20d1a03320f7afc4639
https://doi.org/10.4049/jimmunol.155.4.1951
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2
Direct detection of Mycobacterium tuberculosis in sputum by polymerase chain reaction and DNA hybridization
Autor: F S Nolte, C Thurmond, T Shinnick, B Plikaytis, P S Mitchell, O Okwumabua, B Metchock, J E McGowan, Andrew M. Edwards
Publikováno v: Journal of Clinical Microbiology. 31:1777-1782
A polymerase chain reaction (PCR) assay for the rapid diagnosis of pulmonary tuberculosis was developed by using oligonucleotide primers to amplify a fragment of IS6110, an insertion sequence repeated multiple times in the chromosome of Mycobacterium
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4064a1ce3271bf655291340866231a
https://doi.org/10.1128/jcm.31.7.1777-1782.1993
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3
T cell responses to 60/65 kDa heat shock protein derived peptides in Turkish patients with Behçet's disease
Autor: H, Direskeneli, E, Ekşioglu-Demiralp, S, Yavuz, T, Ergun, T, Shinnick, T, Lehner, T, Akoglu
Publikováno v: The Journal of rheumatology. 27(3)
Sequence homology and cross reactivity between microbial and human heat shock proteins (HSP) led to the concept that HSP might be involved in the etiopathogenesis of Behçet's disease (BD). We investigated T cell responses to 8 synthetic peptides der
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c52c1648dedd02b43dab098fe189b131
https://pubmed.ncbi.nlm.nih.gov/10743813
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4
Role of gamma delta T cells in pathogenesis and diagnosis of Behcet's disease
Autor: A, Hasan, F, Fortune, A, Wilson, K, Warr, T, Shinnick, Y, Mizushima, R, van der Zee, M R, Stanford, J, Sanderson, T, Lehner
Publikováno v: Lancet (London, England). 347(9004)
Behcet's disease (BD) is a multisystem disorder of unknown pathogenesis. The diagnosis is based on a set of international clinical criteria. Previous investigations have suggested that immunological cross-reactivity between peptides within streptococ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5ae8dcb9c527d7c791ae8372cce7e88d
https://pubmed.ncbi.nlm.nih.gov/8667904
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5
T cell epitope expression of mycobacterial and homologous human 65-kilodalton heat shock protein peptides in short term cell lines from patients with Behçet's disease
Autor: K, Pervin, A, Childerstone, T, Shinnick, Y, Mizushima, R, van der Zee, A, Hasan, R, Vaughan, T, Lehner
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 151(4)
T cell epitopes of the 65-kDa heat shock protein (HSP) were mapped in patients with Behçet's disease (BD), by stimulating T cells with the overlapping synthetic peptides derived from the sequences of the Mycobacterium tuberculosis 65-kDa HSP. Signif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c4fb172314573b1e33ceb7dda2a12028
https://pubmed.ncbi.nlm.nih.gov/7688396
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6
Recognition of a peptide antigen by heat shock--reactive gamma delta T lymphocytes
Autor: W, Born, L, Hall, A, Dallas, J, Boymel, T, Shinnick, D, Young, P, Brennan, R, O'Brien
Publikováno v: Science (New York, N.Y.). 249(4964)
Small synthetic peptides that correspond to different portions of the 65-kilodalton mycobacterial heat shock protein (Hsp65) were used to identify a putative antigenic epitope for gamma delta cells. Weaker gamma delta responses to the equivalent port
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::774bcf418891c3a3dadcd0aa274dd272
https://pubmed.ncbi.nlm.nih.gov/1695022
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7
Recognition of heat shock proteins and gamma delta cell function
Autor: W, Born, M P, Happ, A, Dallas, C, Reardon, R, Kubo, T, Shinnick, P, Brennan, R, O'Brien
Publikováno v: Immunology today. 11(2)
Recently evidence has accumulated suggesting that gamma delta cells may participate in the immune response to mycobacteria and other infectious organisms. Many mouse gamma delta cells are stimulated by the 65 kDa heat shock protein of M. bovis and hu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::089bc5cc84a3fb2cbf42bbb560a11071
https://pubmed.ncbi.nlm.nih.gov/2139782
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9
Association between the 65-kilodalton heat shock protein, Streptococcus sanguis, and the corresponding antibodies in Behcet's syndrome
Autor: Y. Mizushima, R. Van Der Zee, Thomas Lehner, R. Smith, T. Shinnick, E. Lavery
Publikováno v: Europe PubMed Central
The etiology of Behcet's syndrome (BS) is unknown, but a number of streptococcal species have been implicated. A hypothesis was postulated that a shared antigen, such as a stress protein, might account for some of these findings. Indeed, a rabbit ant
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6f351bded1dad2ba34a03db9496874
http://europepmc.org/abstract/med/2004821
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10
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