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pro vyhledávání: '"T. Scott McCluskey"'
Autor:
Joshua N. Fletcher, T. Scott McCluskey, Zhonghua Jia, Jay Patrick Slack, A. Douglas Kinghorn, Amy Marie Odley
Publikováno v:
Journal of Agricultural and Food Chemistry. 59:13117-13121
The leaves of the native North American plant, Eriodictyon californicum, were once used to mask the bitter taste of pharmaceuticals, an application currently of importance. Ten flavonoids (1-10) were isolated from the leaves of E. californicum, of wh
Autor:
Carolyn M. Sawyer, Mirela Iodi Carstens, Christopher T. Simons, Jay Patrick Slack, T. Scott McCluskey, Earl Carstens, Stefan Michael Furrer
Publikováno v:
Journal of Neurophysiology. 101:1742-1748
The enigmatic sensation of tingle involves the activation of primary sensory neurons by hydroxy-α-sanshool, a tingly agent in Szechuan peppers, by inhibiting two-pore potassium channels. Central mechanisms mediating tingle sensation are unknown. We
Autor:
Jie Li, Wei Lv, A. Douglas Kinghorn, Ye Deng, Jay Patrick Slack, Joshua N. Fletcher, Mark Cushman, T. Scott McCluskey, Zhonghua Jia, Li Pan, Michael A. Vincent
Publikováno v:
Journal of natural products. 77(7)
In a screening of extracts of selected plants native to Ohio against the human bitterness receptor hTAS2R31, a chloroform-soluble extract of the aerial parts of Solidago canadensis (Canada goldenrod) was determined to have hTAS2R31 antagonistic activ
Autor:
T. Scott McCluskey, Guillaume Blancher, Amanda H. Klein, Stefan Michael Furrer, Mirela Iodi Carstens, Jay Patrick Slack, Earl Carstens, Christopher T. Simons
Publikováno v:
Chemical senses. 36(7)
We presently investigated 2 novel menthol derivatives GIV1 and GIV2, which exhibit strong cooling effects. In previous human psychophysical studies, GIV1 delivered in a toothpaste medium elicited a cooling sensation that was longer lasting compared w
Publikováno v:
Molecular cell biology research communications : MCBRC. 3(4)
We have identified a mammalian homologue of yeast Ump1p by searching for similar proteins in human and mouse expressed sequence tag (EST) databases. Ump1p is an accessory protein that is required for normal proteasome assembly in yeast (1). A mammali
Publikováno v:
The Journal of biological chemistry. 271(33)
Expression of platelet thromboxane receptors is transcriptionally increased during megakaryocytic differentiation stimulated by phorbol 12-myristate 13-acetate (PMA). We previously cloned and characterized the promoter region of the human thromboxane
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