Zobrazeno 1 - 10
of 96
pro vyhledávání: '"T. Schetters"'
Autor:
Aram M. de Haas, Dorian A. Stolk, Sjoerd T. T. Schetters, Laura Goossens-Kruijssen, Eelco Keuning, Martino Ambrosini, Louis Boon, Hakan Kalay, Gert Storm, Hans J. van der Vliet, Tanja D. de Gruijl, Yvette van Kooyk
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 581 (2024)
Cancer vaccines have emerged as a potent strategy to improve cancer immunity, with or without the combination of checkpoint blockade. In our investigation, liposomal formulations containing synthetic long peptides and α-Galactosylceramide, along wit
Externí odkaz:
https://doaj.org/article/2be967ab56b14c11a0144b1c553fc930
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/700654afe1cc4bbf84a6aa48103f20b9
Autor:
Ernesto Rodriguez, Kelly Boelaars, Kari Brown, Katarina Madunić, Thomas van Ee, Frederike Dijk, Joanne Verheij, R. J. Eveline Li, Sjoerd T. T. Schetters, Laura L. Meijer, Tessa Y. S. Le Large, Else Driehuis, Hans Clevers, Sven C. M. Bruijns, Tom O’Toole, Sandra J. van Vliet, Maarten F. Bijlsma, Manfred Wuhrer, Geert Kazemier, Elisa Giovannetti, Juan J. Garcia-Vallejo, Yvette van Kooyk
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Rodriguez et al. present a transcriptomic analysis of glycosylation associated gene profiles, including bulk patient sequencing, sc-RNA seq, cell lines and organoids, to examine glycosylation in PDAC. They find 2 specific glycan profiles correlating
Externí odkaz:
https://doaj.org/article/733f6ecaba10448ebbd86e176c3ab7d9
Autor:
Ernesto Rodriguez, Kelly Boelaars, Kari Brown, R. J. Eveline Li, Laura Kruijssen, Sven C. M. Bruijns, Thomas van Ee, Sjoerd T. T. Schetters, Matheus H. W. Crommentuijn, Joost C. van der Horst, Nicole C. T. van Grieken, Sandra J. van Vliet, Geert Kazemier, Elisa Giovannetti, Juan J. Garcia-Vallejo, Yvette van Kooyk
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Alterations in glycosylation in tumours facilitate tumour progression. Here, the authors show that pancreatic ductal adenocarcinomas present increased sialylation, which stimulates the polarisation of monocytes via Siglec receptors, resulting in the
Externí odkaz:
https://doaj.org/article/64cd1d7410f74f27b60dd9aca97082ae
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Eosinophils are typically a minority population of circulating granulocytes being released from the bone-marrow as terminally differentiated cells. Besides their function in the defense against parasites and in promoting allergic airway inflammation,
Externí odkaz:
https://doaj.org/article/483cb85f53464d408b3e9cbd89adb5a6
Autor:
Louis Boon, Matheus H W Crommentuijn, Sjoerd T T Schetters, Laura J W Kruijssen, Yvette van Kooyk, Ernesto Rodriguez, Jan Van den Bossche, Joke M M Den Haan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background PD1 immune checkpoint blockade (αPD1 ICB) has shown unparalleled success in treating many types of cancer. However, response to treatment does not always lead to tumor rejection. While αPD1 ICB relies on cytotoxic CD8+ T cells, antigen-p
Externí odkaz:
https://doaj.org/article/0b3a381377d2418f88931130ae98ba49
Autor:
Matheus H W Crommentuijn, Sjoerd T T Schetters, Sophie A Dusoswa, Laura J W Kruijssen, Juan J Garcia-Vallejo, Yvette van Kooyk
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Glioblastoma (GBM) is the most common and deadliest form of brain cancer in adults. Standard treatment, consisting of surgery and radiochemotherapy, only provides a modest survival benefit and is incapable of combating infiltrating GBM cel
Externí odkaz:
https://doaj.org/article/bbaf4c24078b4d02844263728c9e3920
Autor:
Sjoerd T. T. Schetters, Laura J. W. Kruijssen, Matheus H. W. Crommentuijn, Hakan Kalay, Jordi Ochando, Joke M. M. den Haan, Juan J. Garcia-Vallejo, Yvette van Kooyk
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The efficacy of vaccination studies aimed at targeting antigens to human DC-SIGN (hDC-SIGN) have been notoriously difficult to study in vivo, as eight dendritic cell-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN) homologs
Externí odkaz:
https://doaj.org/article/18346b8d94814872880ff4fe9ec04205
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
In recent years, many paradigms concerning central nervous system (CNS) immunology have been challenged and shifted, including the discovery of CNS-draining lymphatic vessels, the origin and functional diversity of microglia, the impact of T cells on
Externí odkaz:
https://doaj.org/article/f344877f88fa4e55911224f42bb063c5
Autor:
Dieke, van Dinther, Henrike, Veninga, Salvador, Iborra, Ellen G F, Borg, Leoni, Hoogterp, Katarzyna, Olesek, Marieke R, Beijer, Sjoerd T T, Schetters, Hakan, Kalay, Juan J, Garcia-Vallejo, Kees L, Franken, Lamin B, Cham, Karl S, Lang, Yvette, van Kooyk, David, Sancho, Paul R, Crocker, Joke M M, den Haan
Publikováno v:
Cell reports. 22(6)
Splenic CD169