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pro vyhledávání: '"T. S. Wilke"'
Publikováno v:
Teratology. 50:379-386
The chemotherapeutic agent 5-fluorouracil (5-FU) is teratogenic in a number of species, yet the mechanism(s) of its developmental toxicity are not fully understood. Administration of 5-FU to the pregnant CD rat on day 14 of gestation results in dose-
Publikováno v:
Teratology. 49:122-134
Methanol has widespread applications in industry and manufacturing and is under consideration as an alternative automotive fuel. Human exposure to methanol would be expected to increase if applications expand in coming years. Methanol has been shown
Autor:
D A, Dawson, T S, Wilke
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 19(2)
The joint toxic action for each of three binary combinations of DNA synthesis inhibitors was examined at concentrations that induce malformations in Xenopus laevis embryos. The three compounds, hydroxyurea, cytosine arabinoside, and 5-fluorouracil, w