Výsledky vyhledávání - "T. S. Sellers"

Pharmacokinetics and tissue distribution of SB-251353, a novel human CXC chemokine, after intravenous administration to mice

Autor: T W, Hepburn, T K, Hart, V L, Horton, T S, Sellers, L P, Tobia, J J, Urbanski, W, Shi, C B, Davis

Publikováno v: The Journal of pharmacology and experimental therapeutics. 298(3)

The pharmacokinetics and tissue distribution of SB-251353, a novel truncated form of the human CXC chemokine growth-related gene product beta, were studied after intravenous administration to the mouse (0.1--250 mg/kg). At the lowest dose, the cleara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f4262e59d1daff7fd725328190d74f86
https://pubmed.ncbi.nlm.nih.gov/11504781

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Evaluation of an automated pyrogallol red-molybdate method for the measurement of urinary protein in rats

Autor: K M, Lynch, T S, Sellers, K A, Gossett

Publikováno v: European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies. 34(7)

Methods for quantitating urinary protein differ in their ranges of linearity, technical ease of performance, and applicability to automated analyzers. The Coomassie Brilliant Blue method is widely used but has limited linearity and its tendency to st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::37b92d73d12971834691076f1f98669a
https://pubmed.ncbi.nlm.nih.gov/8864407

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Interspecies pharmacokinetics of a novel hematoregulatory peptide (SKF 107647) in rats, dogs, and oncologic patients

Autor: D R, Brocks, M I, Freed, D E, Martin, T S, Sellers, N, Mehdi, D R, Citerone, V, Boppana, B, Levitt, B E, Davies, J, Nemunaitis, D K, Jorkasky

Publikováno v: Pharmaceutical research. 13(5)

To study the pharmacokinetics of SKF 107647, a novel hematoregulatory agent, in rats, dogs, and patients with non-lymphoid solid tumor malignancy.Sprague Dawley rats and beagle dogs (n = 6 each; 3 M, 3 F) were given 25 mg/kg of SKF 107467 as an iv bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dde7d4890eb0764932712d85e904910f
https://pubmed.ncbi.nlm.nih.gov/8860439

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Hemodynamic, hematologic and eicosanoid mediated mechanisms in 7.5 percent sodium chloride treatment of uncontrolled hemorrhagic shock

Autor: R, Rabinovici, T L, Yue, M M, Krausz, T S, Sellers, K M, Lynch, G, Feuerstein

Publikováno v: Surgery, gynecologyobstetrics. 175(4)

Hypertonic saline solution (HTS) (7.5 percent sodium chloride [NaCl]) treatment (5 milliliters per kilogram) of rats subjected to uncontrolled hemorrhagic shock (n = 7) caused an initial partial recovery of blood pressure (+38 +/- 5 percent, p0.05) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::202653815276bf25b5865f8c9011e077
https://pubmed.ncbi.nlm.nih.gov/1411892

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Pharmacological profile of G619, a new platelet aggregation inhibitor

Autor: Eliot H. Ohlstein, Tian-Li Yue, Giora Z. Feuerstein, A. Sulpizio, M.J. Slivjak, R. Rabinovici, R. Poyser, T. S. Sellers, K. M. Lynch, Edward F. Smith

Publikováno v: Thrombosis research. 66(4)

G619, a 4-OH-isophthalic acid derivative, was studied for its capacity to inhibit platelet aggregation. G619 dose-dependently inhibited U46619, collagen, ADP, PAF, thrombin and epinephrine-induced platelet aggregation in vitro. The IC50 values for in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7016474aa1e33692b7d77c3b1785d148
https://pubmed.ncbi.nlm.nih.gov/1412200

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Reduction in myocardial ischemic/reperfusion injury and neutrophil accumulation after therapeutic administration of streptokinase

Autor: E. F. Smith, A. J. Nichols, T. S. Sellers, S. R. OʼBrien, D. E. Griswold, J. W. Egan, L. M. Hillegass, J. A. Vasko, M. J. Slivjak, P. A. Davis, C. E. Wolff, M. J. DiMartino

Publikováno v: Journal of cardiovascular pharmacology. 18(5)

The benefit of thrombolytic agents to reduce myocardial infarct size, improve left ventricular (LV) function, and prolong survival in human subjects is generally recognized, although the precise mechanism is poorly defined. This study was designed to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf3c0eb8392a336dd705435489c8bce
https://pubmed.ncbi.nlm.nih.gov/1723770

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Use of danazol for treatment of corticosteroid-resistant immune-mediated thrombocytopenia in a dog

Autor: J C, Bloom, L D, Meunier, P A, Thiem, T S, Sellers

Publikováno v: Journal of the American Veterinary Medical Association. 194(1)

A routine health screen of a 7 1/2-year-old female Beagle participating as a control in a long-term study revealed thrombocytopenia. Immune thrombocytopenia was diagnosed on the basis of regenerative bone marrow findings (high number of megakaryocyte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1aa1988eb84ded3722efea62572b7dbc
https://pubmed.ncbi.nlm.nih.gov/2914797

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The effect of human recombinant tissue-type plasminogen activator on clinical and laboratory parameters of hemostasis and systemic plasminogen activation in the dog and the rat

Autor: J C, Bloom, T S, Sellers, G C, Gries, E B, Wheeldon, S R, O'Brien, H B, Lewis

Publikováno v: Thrombosis and haemostasis. 60(2)

The effect of human recombinant tissue-type plasminogen activator (rt-PA) on parameters of hemostasis and systemic plasminogen activation was studied in the dog and rat. Effects on screening coagulation times, fibrinogen concentration, fibrin/fibrino

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::05cd47ae8c874323fff736b8feb8108e
https://pubmed.ncbi.nlm.nih.gov/3146143

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