Zobrazeno 1 - 10
of 67
pro vyhledávání: '"T. S. Oretskaya"'
Autor:
Valeri Metelev, T. S. Oretskaya
Publikováno v:
Russian Journal of Bioorganic Chemistry
Nucleic acids have made a long and arduous journey "from the bench to the bedside." At present, it can be assumed that drugs based on modified oligonucleotides will find a worthy application in personalized medicine of the future.
Autor:
Peter Friedhoff, Elena A. Kubareva, T. S. Oretskaya, R. M. Trikin, Elena A. Romanova, Valeri Metelev, M. V. Monakhova, E. M. Kosaretskiy, S. A. Perry
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:447-460
Noncovalent interactions between DNA and proteins are vital for cells. DNA-protein crosslinking may occur due to various endogenous and exogenous factors, as well as chemotherapeutic agents, and often affects the performance of DNA-binding proteins.
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:478-482
Investigation of RNAs with a length less than 30 nucleotides, in particular, microRNAs and other extremely short noncoding RNAs, is often associated with difficulties in detecting them not only in vivo, but also in vitro. One of these molecules is ba
Autor:
L. A. Abrosimova, A. R. Samsonova, T. A. Perevyazova, A. K. Yunusova, R. I. Artyukh, E. A. Romanova, L. A. Zheleznaya, T. S. Oretskaya, E. A. Kubareva
Publikováno v:
Molecular Biology. 54:599-610
Autor:
Elena A. Kubareva, A. S. Semkina, Elena A. Romanova, Desirazu N. Rao, T. S. Oretskaya, Timofei S. Zatsepin, M. V. Monakhova, D. S. Naberezhnov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 45:144-154
Diketone DNA derivatives have been proposed to modify the guanidine group of Arg in proteins. The β-diketo group at the C2' atom of the sugar phosphate moiety has been introduced in DNA by acylation of oligonucleotide precursors, i.e., DNA fragments
Autor:
Anzhela V. Pavlova, Gabriele Klug, Andrei V. Alexeevski, Vladimir G. Lunin, Peter Friedhoff, M. V. Monakhova, Elena A. Kubareva, A I Penkina, T. S. Oretskaya, V V Kucherenko, A M Lyaschuk
Publikováno v:
Biochemistry (Moscow). 83:281-293
We have purified the MutL protein from Rhodobacter sphaeroides mismatch repair system (rsMutL) for the first time. rsMutL demonstrated endonuclease activity in vitro, as predicted by bioinformatics analysis. Based on the alignment of 1483 sequences o
Autor:
T. S. Oretskaya, S. A. Kuznetsova
Publikováno v:
Russian Chemical Reviews. 85:445-463
Publikováno v:
Acta Naturae
Non-coding RNAs up to 1,000 nucleotides in length are widespread in eukaryotes and fulfil various regulatory functions, in particular during chromatin remodeling and cell proliferation. These RNAs are not translated into proteins: thus, they are non-
Autor:
E. V. Kazanova, Elena A. Kubareva, Nina G. Dolinnaya, Boris S. Naroditsky, Alexander L. Gintsburg, T. S. Oretskaya, N A Zigangirova
Publikováno v:
Russian Chemical Reviews. 77:967-981
The nuclear factor κB (NF-κB) is a transcription factor involved in inducible expression of cellular genes playing a key role in cardiovascular pathologies, carcinogenesis, inflammatory and viral diseases. The review describes the stimuli and proce
Autor:
V. Kachalova, Evgeny M. Zubin, E. V. Kazanova, Dmitry A. Stetsenko, Michael J. Gait, T. S. Oretskaya
Publikováno v:
Russian Chemical Bulletin. 56:806-814
Oligo-2′-O-methylribonucleotides containing residues of phenylalanine, histidine, and lysine amides were synthesized with the use of new phosphoramidites of 2′-aminoacid derivatives of uridine.