Zobrazeno 1 - 10
of 16
pro vyhledávání: '"T. S. Nepomnyashchikh"'
Publikováno v:
Медицинская иммунология, Vol 21, Iss 2, Pp 221-230 (2019)
To date, cancer diseases are one of the leading causes of mortality and morbidity in the world. Recent advances in understanding the molecular genetic mechanisms of oncogenesis and anti-cancer immune responses open new opportunities for the developme
Externí odkaz:
https://doaj.org/article/c797440fe6244527ad58c8df1f2d8ed5
Autor:
T. S. Nepomnyashchikh, T. V. Tregubchak, S. N. Yakubitskiy, O. S. Taranov, R. A. Maksyutov, S. N. Shchelkunov
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 21, Iss 3, Pp 317-322 (2017)
Rheumatoid arthritis (RA) is a serious systemic disease of connective tissue, mainly affecting joints but also with different extra-articular manifestations. In the course of RA the degenerative changes occur in cartilage surfaces of affected joints
Externí odkaz:
https://doaj.org/article/1cb5aca7018148649baa11ae6d26c75d
Publikováno v:
Медицинская иммунология, Vol 19, Iss 2, Pp 127-144 (2017)
Over last decade, a substantial progress has been made, with respect to understanding of cancer biology and its interplay with the host immune system. Different immunotherapeutic drugs based on recombinant cytokines and monoclonal antibodies are wide
Externí odkaz:
https://doaj.org/article/2b2e74cb209d4fa0b24f5f2f85dca31b
Autor:
Stanislav N Yakubitskiy, O. S. Taranov, T. S. Nepomnyashchikh, Sergei N. Shchelkunov, Nesterov Ae
Publikováno v:
Acta Naturae. 8:110-117
We propose a model of rheumatoid arthritis (RA) induced in outbred guinea pigs using a single subcutaneous injection of complete Freunds adjuvant to the hind paw. Histological examination of this model shows fibrin deposition on the surface of the sy
Publikováno v:
Russian Journal of Genetics. 52:543-556
Gene therapy can offer a new approach to arthritis treatment which acts at an inflammation site. Numerous studies show high efficacy of gene therapy in different models of arthritis in humans. Even a single injection of a recombinant vector results i
Autor:
Sergey E. Peltek, Nikolay A. Kolchanov, S. V. Shekhovtsov, Sergei N. Shchelkunov, T V Tregubchak, T. S. Nepomnyashchikh
Publikováno v:
Doklady Biochemistry and Biophysics. 462:176-180
Publikováno v:
Acta Naturae
We propose a model of rheumatoid arthritis (RA) induced in outbred guinea pigs using a single subcutaneous injection of complete Freund’s adjuvant to the hind paw. Histological examination of this model shows fibrin deposition on the surface of the
Publikováno v:
Molecular Biology. 44:939-947
Orthopoxviral genomes bear genes for a series of homologous secreted proteins binding tumor necrosis factor (TNF). Orthopoxvirus species have different sets of these proteins. Variola virus has only one protein of this series, CrmB. Although CrmB pro
Publikováno v:
Biochemistry (Moscow). 74:1356-1362
Gel-filtration chromatographic separation of the lysate of Sf21 insect cells infected with recombinant baculovirus BVi67 containing the gene for TNF-binding protein (CrmB) of variola virus (VARV) revealed that hTNF-cytotoxicity neutralization activit
Autor:
I. N. Babkina, T. S. Nepomnyashchikh, Rinat A. Maksyutov, Gutorov Vv, Sergei N. Shchelkunov, I. V. Babkin
Publikováno v:
Molecular Biology. 42:543-553
Two segments of the variable terminal regions of the variola virus (VARV) genome were sequenced in 22 strains from the Russian collection, including about 13.5 kb of the left segment and about 10.5 kb of the right segment. The total length of the seq