Zobrazeno 1 - 10
of 41
pro vyhledávání: '"T. S. Khlebnikova"'
Autor:
E. M. Tumar, O. V. Panibrat, V. G. Zinovich, Yu. A. Piven, S. E. Ogurtsova, Fedor A. Lakhvich, T. S. Khlebnikova
Publikováno v:
Pharmaceutical Chemistry Journal. 55:219-223
The cytotoxic activity of perfluoroalkyl imidazoindazoles and imidazobenzisoxazoles with respect to MCF-7 (human breast carcinoma) and HepG2 cell lines (human hepatocellular carcinoma) was studied. The imidazoindazoles exhibited significant cytotoxic
Autor:
Olga V. Mikolaichuk, E. V. Lider, R. E. Trifonov, Fedor A. Lakhvich, G. K. Ovsepyan, A. A. Batyrenko, Aleksandra V. Protas, T. S. Khlebnikova, Yu. A. Eremina, Ilya V. Kornyakov
Publikováno v:
Russian Journal of General Chemistry. 91:666-671
A series of palladium(II) complexes with 1H- and 2H-tetrazole ligands (2-isopropyl-5-R-2H-tetrazoles and 1H-tetrazol-1-ylcarboxylic acids) was synthesized. Structure of the obtained compounds was confirmed by 1H and 13C NMR spectroscopy, high-resolut
Autor:
O. V. Panibrat, É. B. Rusanov, V. G. Zinovich, Fedor A. Lakhvich, S. E. Ogurtsova, A. V. Baranovskii, T. S. Khlebnikova, Yu. A. Piven
Publikováno v:
Pharmaceutical Chemistry Journal. 54:700-706
The oximes of fluorine-containing 6,7-dihydroindazole-4,5-diones and 6,7-dihydrobenzisoxazole-4-5-diones, 5-[3-fluorobenzoyloxy)imino)]-6,6-dimethyl-3-(3-fluorophenyl)-6,7-dihydrobenz[d]]isoxazol-4(5H)-one, and 5,5-dimethyl-7-phenyl-9-(4-fluorophenyl
Autor:
Alexander V. Baranovsky, V. G. Isakova, Yu. A. Piven, T. S. Khlebnikova, V. A. Smaliak, Fedor A. Lakhvich
Publikováno v:
Russian Journal of General Chemistry. 90:746-749
Synthesis of regioisomeric 8-trifluoromethyl-4,5-dihydro-3H-imidazo[4',5':5,6]benz[1,2-d]isoxazoles and 8-trifluoromethyl-4,5-dihydro-3H-imidazo[4',5':3,4]benz[1,2-c]isoxazolones was realized by one-pot oxidation of 3-trifluromethyl-6,7-dihydrobenz[d
Autor:
T. S. Khlebnikova, Fedor A. Lakhvich, I. V. Sorokina, Yu. A. Piven, T. S. Frolova, T. G. Tolstikova
Publikováno v:
Chemistry of Natural Compounds. 54:1100-1105
Conjugates of betulinic acid with 2-(fluoroacyl)cycloalkane-1,3-dione motifs were synthesized by reacting 3-chloro-2-(fluoroacyl)-2-cycloalkene-1-ones with an equivalent amount of betulinic acid aminoalkylamide hydrochlorides in the presence of Et3N
Autor:
A. A. Batyrenko, O. V. Mikolaichuk, G. K. Ovsepyan, A. V. Protas, I. V. Kornyakov, E. V. Lider, Yu. A. Eremina, T. S. Khlebnikova, F. A. Lakhvich, R. E. Trifonov
Publikováno v:
Russian Journal of General Chemistry. 91:1260-1260
Publikováno v:
Chemistry of Heterocyclic Compounds. 53:1254-1260
Regioisomeric fluorine-containing 6,7-dihydro-1,2-benzisoxazol-4(5Н)-ones and 6,7-dihydro-2,1-benzisoxazol-4(5Н)-ones were prepared by reactions of 2-(fluorobenzoyl)cyclohexane-1,3-diones or their methyl enol ethers with hydroxylamine.
Publikováno v:
Russian Journal of Organic Chemistry. 51:650-656
Refluxing 3-perfluoroalkyl-6,7-dihydro-1H-indazol-4(5H)-ones with 4-fold excess of hydroxylamine hydrochloride in pyridine afforded their (E)-oximes. The obtained oximes were alkylated with ethyl iodide and acylated with carboxylic acids chlorides to
Publikováno v:
Russian Journal of General Chemistry. 84:465-473
The interaction of aromatic amines (4-fluorinebenzylamine, 3-trifluoromethylbenzylamine, 4-fluoroaniline, or 3,4-difluoroaniline) with either 2-acylcyclopentane-1,3-diones (fluorine-substituted or fluorine-free) or their enol derivatives (chlorovinyl
Publikováno v:
Russian Journal of Organic Chemistry. 49:421-427
Oxidation of 1-aryl-3-perfluoroalkyl-6,7-dihydro-1H-indazol-4(5H)-ones with selenium dioxide in the presence of sulfuric acid in glacial acetic acid, followed by treatment of 6,7-dihydro-1H-indazole-4,5-diones thus obtained with an equimolar amount o