Zobrazeno 1 - 7
of 7
pro vyhledávání: '"T. S. Karin Eisinger-Mathason"'
Autor:
Michael S. Nakazawa, T. S. Karin Eisinger-Mathason, Navid Sadri, Joshua D. Ochocki, Terence P. F. Gade, Ruchi K. Amin, M. Celeste Simon
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Hypoxia is a common feature of soft tissue sarcomas, resulting in the activation of HIF-1α, which promotes metastasis. Here, Nakazawa et al. show that paradoxically HIF-2α is epigenetically silenced during the progression of multiple sarcoma subtyp
Externí odkaz:
https://doaj.org/article/95b0d41802c54d1d8d017de48e65cd93
Autor:
Ashley M. Fuller, Ann DeVine, Ileana Murazzi, Nicola J. Mason, Kristy Weber, T. S. Karin Eisinger-Mathason
Publikováno v:
Cellular Oncology. 45:1277-1295
Autor:
Hawley C. Pruitt, Ashley M. Fuller, Hoogeun Song, Ying Liu, Ann DeVine, Rohan Katti, Samir Devalaraja, Gabrielle E. Ciotti, Michael Gonzalez, Erik F. Williams, Ileana Murazzi, Nicolas Skuli, Hakon Hakonarson, Kristy Weber, Malay Haldar, Joseph A. Fraietta, Sharon Gerecht, T. S. Karin Eisinger-Mathason
CD8+ T cell dysfunction is a critical barrier to anti-tumor immunity, but molecular mechanisms underlying the regulation of T cell dysfunction in solid tumors are diverse and complex. Extracellular matrix (ECM) composition facilitates solid tumor pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7429eee4f90250c96407dbf751f331f
https://doi.org/10.1101/2022.03.31.486627
https://doi.org/10.1101/2022.03.31.486627
Autor:
Ashley M. Fuller, Ann DeVine, Ileana Murazzi, Nicola J. Mason, Kristy Weber, T. S. Karin Eisinger-Mathason
Undifferentiated pleomorphic sarcoma (UPS), an aggressive subtype of soft-tissue sarcoma (STS), is exceedingly rare in humans and lacks effective, well-tolerated therapies. In contrast, STS are relatively common in canine companion animals; thus, inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed4f6d3baec103d40c074f3482687bf3
https://doi.org/10.1101/2021.12.22.473852
https://doi.org/10.1101/2021.12.22.473852
Publikováno v:
Nature. 610:607-607
Autor:
Ashley M. Fuller, Hawley C. Pruitt, Hoogeun Song, Ying Liu, Ann Devine, Rohan S. Katti, Samir Devalaraja, Gabrielle E. Ciotti, Michael Gonzalez, Erik F. Williams, Ileana Murazzi, Nicolas Skuli, Hakon Hakonarson, Kristy Weber, Malay Haldar, Joseph A. Fraietta, Sharon Gerecht, T. S. Karin Eisinger-Mathason
Publikováno v:
Clinical Cancer Research. 28:PR001-PR001
CD8+ T cell dysfunction, characterized by reduced effector function, impaired proliferation, and inhibitory receptor upregulation, is a fundamental barrier to anti-tumor immunity. However, molecular mechanisms underlying the regulation of CD8+ T cell
Publikováno v:
Advances in experimental medicine and biology. 1136
Metastasis remains the leading cause of cancer-related deaths. To date, there are no specific treatments targeting disseminated disease. New therapeutic options will become available only if we enhance our understanding of mechanisms underlying metas